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pro vyhledávání: '"Lilly van de Venn"'
Autor:
Lukas Möller, Eric J. Aird, Markus S. Schröder, Lena Kobel, Lucas Kissling, Lilly van de Venn, Jacob E. Corn
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
CRISPR-Cas induced HDR methods tend to have a low efficiency. Here the authors report an HDR improvement strategy, Recursive Editing, that selectively retargets undesired indel outcomes to create additional opportunities for HDR; they introduce REtar
Externí odkaz:
https://doaj.org/article/83ac27ad86f2469d94b37a80c62ba679
Autor:
Lilly van de Venn
Genome editing using nucleases such as CRISPR-Cas induces programmable DNA damage at a target genomic site, but can also affect off-target sites. We develop a powerful assay for the unbiased identification of off-target sites that we term DISCOVER-se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67fd993511a108da453099aedb6ebdc3
https://doi.org/10.17504/protocols.io.kqdg349ypl25/v2
https://doi.org/10.17504/protocols.io.kqdg349ypl25/v2