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pro vyhledávání: '"Lilly Y.W. Bourguignon"'
Autor:
Lilly Y.W. Bourguignon
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Frontiers in Oncology
Frontiers in Oncology
Tumor malignancies involve cancer cell growth, issue invasion, metastasis and often drug resistance. A great deal of effort has been placed on searching for unique molecule(s) overexpressed in cancer cells that correlate(s) with tumor cell-specific b
Autor:
Neil Schneiderman, Arthur LaPerriere, Michael H. Antoni, Lilly Y.W. Bourguignon, Mary A Fletcher
Publikováno v:
Stress and Disease Processes ISBN: 9781315827490
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d6d8e5caa4b37d7d511766e7daedfc6
https://doi.org/10.4324/9781315827490-8
https://doi.org/10.4324/9781315827490-8
Publikováno v:
Matrix biology : journal of the International Society for Matrix Biology.
Head and neck squamous cell carcinoma (HNSCC) is a malignancy that often involves the oral cavity, pharynx, larynx, or paranasal sinuses. There is a compelling evidence of the human papilloma virus including HPV16 E6 oncogene drives cell transformati
Autor:
Lilly Y.W. Bourguignon
Publikováno v:
Molecular Determinants of Head and Neck Cancer ISBN: 9783319787619
Head and neck squamous cell carcinoma (HNSCC) is an aggressive disease associated with high morbidity and mortality. Hyaluronan (HA), a major component in the extracellular matrix (ECM) of most mammalian tissues, is accumulated in many types of tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::417cc0f3be5fed7dda7bd8171301be68
https://doi.org/10.1007/978-3-319-78762-6_19
https://doi.org/10.1007/978-3-319-78762-6_19
Publikováno v:
Head & Neck. 35:511-520
Background. CD44 is a transmembrane receptor found on many different benign and malignant cells. Hyaluronan (HA), a major component of the extracellular matrix, is the primary ligand for CD44 receptors. In cancer cells, HA interaction with CD44 promo
Autor:
Lilly Y.W. Bourguignon
Publikováno v:
Small GTPases
Small GTPases, vol 3, iss 1
Small GTPases, vol 3, iss 1
MicroRNAs are often associated with the pathogenesis of many cancers, including head and neck squamous cell carcinoma (HNSCC). In particular, microRNA-21 (miR-21) appears to have a critical role in tumor cell survival, chemoresistance and HNSCC progr
Publikováno v:
Cytoskeleton. 68:671-693
Both high and low molecular weight hyaluronan (HMW-HA vs. LMW-HA) exist in various tissues and cells. In this study, we investigated LMW-HA-mediated CD44 interaction with Toll-like receptors (TLRs), the actin filament-associated protein (AFAP-110), a
Autor:
Christina C. Spevak, Lilly Y.W. Bourguignon, Gabriel Wong, Christine Earle, Katherine C. Krueger
Publikováno v:
Oncogene
Oncogene, vol 31, iss 2
Oncogene, vol 31, iss 2
MicroRNAs are often associated with the pathogenesis of many cancers including Head and Neck Squamous Cell Carcinoma (HNSCC). In particular, microRNA-21 (miR-21) appears to play a critical role in tumor cell survival, chemoresistance and HNSCC progre
Autor:
Lilly Y.W. Bourguignon, Gabriel Wong, Katherine C. Krueger, Christine Earle, Christina C. Spevak
Publikováno v:
Journal of Biological Chemistry. 285:36721-36735
Dysregulation of microRNAs is observed in many cancers, including breast cancer. In particular, miR-10b appears to play an important role in tumor cell invasion and breast cancer progression. In this study, we investigated hyaluronan (HA)-induced CD4
Autor:
Lilly Y.W. Bourguignon, Wenyan Man, M. Man, Yan Wu, Peter M. Elias, Mao-Qiang Man, Kenneth R. Feingold
Publikováno v:
Experimental Dermatology. 18:962-968
CD44 is a transmembrane glycoprotein expressed in various tissues including the skin. Previous studies indicated that CD44 is required for epidermal permeability barrier homeostasis and keratinocyte differentiation. Yet, while some studies have demon