Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Lillian Shuk-Nga Chow"'
Autor:
Joseph Kwong, Kwok-Wai Lo, Lillian Shuk-Nga Chow, Ka-Fai To, Kwong-Wai Choy, Franky Leung Chan, Samuel C. Mok, Dolly P. Huang
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 7, Iss 1, Pp 67-74 (2005)
Aberrant retinoid signaling in human cancers is extending from the nucleus to the cytoplasm. Recently, we have demonstrated frequent epigenetic inactivation of a retinoic acid receptor (RAR), RARβ2, in nasopharyngeal carcinoma (NPC). To further expl
Externí odkaz:
https://doaj.org/article/5971aa2be98a43379fb5fcf202247f22
Autor:
Kwok Wai Lo, Cornelia Man, Billy K. C. Chow, Leo T. O. Lee, Vien H. Y. Lee, Sai Wah Tsao, Lillian Shuk-Nga Chow
Publikováno v:
Gene. 443:55-63
RASSF1A, which is frequently found inactivated in human cancers, is revealed as a tumor suppressor gene in nasopharyngeal carcinoma (NPC). Using RASSF1A-expressing (NP69 and HK-1) and non-RASSF1A-expressing (C666-1) cell models, the transcriptional r
Autor:
Ka Fai To, Kam Sze Tsang, Lillian Shuk-Nga Chow, Reinhard Dammann, Ching-Wan Lam, Dolly P. Huang, Kwok Wai Lo, Joseph Kwong
Publikováno v:
International Journal of Cancer. 109:839-847
Deletion on the short arm of chromosome 3 is one of the most important genetic abnormalities in the tumorigenesis of nasopharyngeal carcinoma (NPC). Both physical mapping and functional studies have targeted an NPC-related tumor suppressor gene(s) to
Autor:
Xianghong Wang, Sai Wah Tsao, Jonathan S.T. Sham, Y.C. Wong, Lillian Shuk-Nga Chow, Dora L.W. Kwong, John M. Nicholls
Publikováno v:
Anti-Cancer Drugs. 13:957-964
The use of cisplatin as a potential radiosensitizer in nasopharyngeal carcinoma (NPC) has produced encouraging results in clinical trials. In order to provide information on improving the design of clinical treatments, we investigated the effect of c
Autor:
Ka Fai To, Wing-Ki Hung, Joseph Kwong, Lillian Shuk-Nga Chow, Albert Yue-Hang Wong, Grace Tin-Yun Chung, Yataro Daigo, Yusuke Nakamura, Dolly P. Huang, Franky L. Chan, Kwok Wai Lo
Publikováno v:
Genes, chromosomescancer. 46(2)
Deletion of the short arm of chromosome 3 is a common event in nasopharyngeal carcinoma (NPC), suggesting that one or more tumor suppressor genes at 3p are involved in this cancer. DLEC1, Deleted in Lung and Esophageal Cancer 1, located at 3p22.2, wa
Publikováno v:
International journal of cancer. 113(3)
Tazarotene-induced gene 1 (TIG1) and Tazarotene-induced gene 3 (TIG3) are retinoid acid (RA) target genes as well as candidate tumor suppressor genes in human cancers. In our study, we have investigated the expression of TIG1 and TIG3 in nasopharynge
Autor:
Sylvia Yat-Yee Chan, Lillian Shuk-Nga Chow, Joseph Kwong, Peter M.L. Teo, Angela Bik-Yu Hui, Andrew K Chan, Dolly P. Huang, Kwok Wai Lo, Eric Ching-Wan Lam
Publikováno v:
Molecular carcinogenesis. 38(4)
Deletion of 11q23 is a common genetic aberration in nasopharyngeal carcinoma (NPC). Multiple candidate tumor suppressor genes (TSG) were mapped to this region but few of them were investigated in NPC. TSLC1 (tumor suppressor in lung cancer) is recent
Autor:
Dora L.W. Kwong, Xianghong Wang, S. C. H. Wong, Yong-Chuan Wong, Jonathan S.T. Sham, Lillian Shuk-Nga Chow, John M. Nicholls, Sai Wah Tsao, Jin Wang, Yu Liu
Publikováno v:
Life sciences. 67(22)
Gossypol, a male contraceptive drug extracted from cottonseeds, has been found to have antiproliferative activity on tumour cells and is thought to be a potential anticancer drug. The aim of this study was to investigate the mechanisms of gossypol-in
Autor:
Sai Wah Tsao, Xianghong Wang, Jst Sham, Lillian Shuk-Nga Chow, Dora L.W. Kwong, John M. Nicholls
Publikováno v:
International Journal of Oncology.
The p16INK4a tumor suppressor gene is frequently inactivated in nasopharyngeal carcinoma (NPC) and hence it may play an important role in the suppression of this tumor. In order to study the effect of p16INK4a restoration in NPC cells, full-length hu
Autor:
Yu Liu, Xianghong Wang, Sai Wah Tsao, John M. Nicholls, S. C. H. Wong, Lillian Shuk-Nga Chow, Dora L.W. Kwong, Jin Wang, Jst Sham
Publikováno v:
International Journal of Oncology.
In a recent study, it was shown that DNA damaging agent cisplatin-induced growth arrest and cell death in cancer cells by a pathway sharing some of the characteristics of replicative senescence. The aim of this study was to determine the role of p53,