Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Lillian S L Ting"'
Autor:
Mary H H Ensom, Chantal Guillemette, Olivier Bernard, Marie-Odile Benoit-Biancamano, K. Wayne Riggs, Lillian S L Ting
Publikováno v:
Pharmacotherapy. 30:1097-1108
Study Objective. To assess the contribution of polymorphisms in the uridine diphosphate glucuronosyltransferase gene (UGT) and the multidrug resistance-associated protein 2 gene (ABCC2) to mycophenolic acid (MPA) pharmacokinetics and clinical outcome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffb1c8b4ce7185c14ae13342d3856a9d
https://doi.org/10.1592/phco.30.11.1097
https://doi.org/10.1592/phco.30.11.1097
Autor:
Nilufar Partovi, Lillian S L Ting, Mai Al-Khatib, Marc Levine, R. Jean Shapiro, Mary H H Ensom
Publikováno v:
Annals of Pharmacotherapy. 44:19-27
Mycophenolate mofetil is widely used in islet transplant recipients and its active metabolite, mycophenolic acid (MPA), exhibits wide pharmacokinetic variability. However, to our knowledge, no limited sampling strategy (LSS) exists for monitoring MPA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::622de34e716bebad979e062dd30b059b
https://doi.org/10.1345/aph.1m511
https://doi.org/10.1345/aph.1m511
Publikováno v:
Therapeutic Drug Monitoring. 30:282-291
Mycophenolate mofetil is an immunosuppressant commonly used in solid organ transplantation. Its active metabolite, mycophenolic acid (MPA), is metabolized to the inactive 7-O-mycophenolic acid glucuronide (MPAG) and the active acyl glucuronide (AcMPA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff18763eb8cc09a6ea93c7e9e7817661
https://doi.org/10.1097/ftd.0b013e318166eba0
https://doi.org/10.1097/ftd.0b013e318166eba0
Publikováno v:
Annals of Pharmacotherapy. 40:1509-1516
Background: Mycophenolic acid (MPA) is the active metabolite of mycophenolate mofetil, an immunosuppressive agent commonly used in solid organ transplantation. MPA is metabolized to the inactive metabolite 7-O-mycophenolic acid glucuronide (MPAG) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bf336d0880f3c64bc82eb6b830ea83d
https://doi.org/10.1345/aph.1h149
https://doi.org/10.1345/aph.1h149
Publikováno v:
Pharmacotherapy. 26:1232-1240
Study Objective. To develop limited sampling strategies for estimation of mycophenolic acid exposure (by determining area under the concentration-time curve [AUC]) in lung transplant recipients by using sampling times within 2 hours after drug admini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a300ffd5f6669a4544e2f93ee5057966
https://doi.org/10.1592/phco.26.9.1232
https://doi.org/10.1592/phco.26.9.1232
Beyond Cyclosporine: A Systematic Review of Limited Sampling Strategies for Other Immunosuppressants
Publikováno v:
Therapeutic Drug Monitoring. 28:419-430
Therapeutic drug monitoring has gained much attention in the management of immunosuppressive therapy. Area under the plasma drug concentration-time curve (AUC) is the pharmacokinetic (PK) parameter most commonly used to assess total exposure to a dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b653aa3dc165f00f27343a23ccf70ed
https://doi.org/10.1097/01.ftd.0000211810.19935.44
https://doi.org/10.1097/01.ftd.0000211810.19935.44
Publikováno v:
Therapeutic drug monitoring. 32(3)
Given the paucity of data on pharmacokinetics of mycophenolic acid (MPA) in islet transplant, the aim of this study was to characterize pharmacokinetic parameters of MPA and its 2 glucuronidated metabolites in stable islet transplant recipients. Sixt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d60d6a4145366cb8cba93260a60a8e48
https://pubmed.ncbi.nlm.nih.gov/20357699
https://pubmed.ncbi.nlm.nih.gov/20357699
Publikováno v:
The Annals of pharmacotherapy. 42(7)
To review the current clinical evidence on the effects of corticosteroid interactions with the immunosuppressive drugs cyclosporine, tacrolimus, mycophenolate, and sirolimus.Articles were retrieved through MEDLINE (1966-February 2008) using the terms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d14274b1403e0c3a2fea1d47f97b3c0
https://pubmed.ncbi.nlm.nih.gov/18594053
https://pubmed.ncbi.nlm.nih.gov/18594053
Publikováno v:
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 27(3)
Background and Methods Eight limited sampling strategies (LSSs) for estimating mycophenolic acid area under the concentration–time curve (4 developed from lung transplant recipients at our center, 4 developed for heart transplant recipients from ot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::732dbf37a154b72885a40707a573e332
https://pubmed.ncbi.nlm.nih.gov/18342756
https://pubmed.ncbi.nlm.nih.gov/18342756
Publikováno v:
Clinical pharmacokinetics. 46(6)
Despite evidence in the literature suggesting that a strong correlation exists between the pharmacokinetic parameters and pharmacodynamic effect of anticancer agents, many of these agents are still dosed by body surface area. Therapeutic drug monitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a8506dec1cfc5942f416952d6969d9f
https://pubmed.ncbi.nlm.nih.gov/17518507
https://pubmed.ncbi.nlm.nih.gov/17518507