Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lillian E. Vickery"'
Autor:
Jon A. Klover, Francis M. Sverdrup, Lillian E. Vickery, Lily R.-H. Song, Charles P. Anglin, Thomas P. Misko, Matthew P. Yates
Publikováno v:
Osteoarthritis and Cartilage. 18(7):948-955
Summary Objective Statins possess anti-inflammatory properties. This study was undertaken to characterize the mechanism of action of statin drugs on collagenase expression in primary human osteoarthritic cartilage tissue. Method Human articular chond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c210d0354aa455ac6deeb35e05b9a42
Autor:
Francis M. Sverdrup, Lillian E. Vickery, Dean J. Aguiar, Scott L. Weinrich, Matthew P. Yates, Poonam Aggarwal, Sue A. Yocum, Adam Skepner, Steven L. Settle, Debra Kellner
Publikováno v:
Cartilage
Insulin-like growth factor binding protein 5 (IGFBP-5) has been proposed to promote cartilage anabolism through insulin-like growth factor (IGF-1) signaling. A proteolytic activity towards IGFBP-5 has been detected in synovial fluids from human osteo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00f83bc9d3ac0935dcb27f2ed34436df
https://pubmed.ncbi.nlm.nih.gov/26069535
https://pubmed.ncbi.nlm.nih.gov/26069535
Autor:
Philip R. Streeter, William F. Hood, Tammy L. Thurman, John P. McKearn, Joseph K. Welply, Larry E Kahn, Woulfe Susan L, Nancy I. Minster, Joseph B. Monahan, Lillian E Vickery
Publikováno v:
Experimental Hematology. 29:41-50
Objective The progenipoietins, a class of engineered proteins containing both fetal liver tyrosine kinase-3 and granulocyte colony-stimulating factor receptor agonist activities, were functionally characterized in vitro and in vivo. Materials and Met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d90635cd6e1fbecfb24c032d0c2be6da
https://doi.org/10.1016/s0301-472x(00)00616-0
https://doi.org/10.1016/s0301-472x(00)00616-0
Autor:
Alison M. Bendele, Olga V. Nemirovskiy, Lillian E. Vickery, Peter G. Ruminski, Mark E. Schnute, T. Sunyer, Steven L. Settle, Tom Vidmar, Dean Messing
Publikováno v:
Arthritis and rheumatism. 62(10)
Objective To demonstrate that the novel highly selective matrix metalloproteinase 13 (MMP-13) inhibitor PF152 reduces joint lesions in adult dogs with osteoarthritis (OA) and decreases biomarkers of cartilage degradation. Methods The potency and sele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9632debcec8d6e12ff8e1d16308eec76
https://pubmed.ncbi.nlm.nih.gov/20533541
https://pubmed.ncbi.nlm.nih.gov/20533541
Autor:
Brandon Collins, W. Howard Roark, Katherine E. Palmquist, Grace E. Munie, Mark E. Schnute, Olga V. Nemirovskiy, Patrick Michael Ann Arbor La Ann Arbor O'brien, Jeffrey A. Scholten, Karl W. Aston, Jeffery N. Carroll, Lillian E. Vickery, T. Sunyer, Steven L. Settle, Joe Nahra, Hanau Cathleen E, Bruce C. Hamper, Peter G. Ruminski, Patt William Chester, Jeffrey Hitchcock, Mark Morris, Huey S. Shieh, Theresa R. Fletcher, Chiu-Fai Man, Joseph J. McDonald, Adam R. Johnson, Michael David Rogers, Arthur J. Wittwer, Alexander Pavlovsky, Richard D. Dyer, Arun Agawal
Publikováno v:
Bioorganicmedicinal chemistry letters. 20(2)
Potent, highly selective and orally-bioavailable MMP-13 inhibitors have been identified based upon a (pyridin-4-yl)-2H-tetrazole scaffold. Co-crystal structure analysis revealed that the inhibitors bind at the S(1)(') active site pocket and are not l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7d21a6adaf1297782797ee424c48361
https://pubmed.ncbi.nlm.nih.gov/20005097
https://pubmed.ncbi.nlm.nih.gov/20005097
Autor:
D.M. Messing, Olga V. Nemirovskiy, A. Bendele, Lillian E. Vickery, M-P. Hellio Le Graverand-Gastineau, M.E. Schnute, T. Sunyer, S.L. Settle, P.G. Ruminski
Publikováno v:
Osteoarthritis and Cartilage. 16:S14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a86b13bd4be6a906a4ec71d444259998
https://doi.org/10.1016/s1063-4584(08)60049-7
https://doi.org/10.1016/s1063-4584(08)60049-7