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pro vyhledávání: '"Lillian E. Baker"'
Autor:
Lillian E. Baker
Publikováno v:
The Journal of Experimental Medicine
Experiments designed to ascertain the reason for the cessation of growth of heart fibroblasts when they are cultivated in a plasma coagulum with embryo juice as nutrient fluid have shown that it is due, first, to the gradual removal of serum from the
Autor:
Lillian E. Baker
Publikováno v:
The Journal of Experimental Medicine
Monocytes from blood and from spleen have been cultivated in fluid medium in Carrel flasks for over 2 months. Diluted serum supplied all the essential nutritive substances. Cultivation in fluid was made possible by adjusting the initial pH of the flu
Autor:
Lillian E. Baker
Publikováno v:
The Journal of Experimental Medicine
It has been found that the enzymatic digestion products of proteins cause a rapid proliferation of blood monocytes in vitro. Digestion mixtures having anywhere from 12 to 68 per cent of their nitrogen in the amino form possess this property. For cont
Autor:
Alexis Carrel, Lillian E. Baker
Publikováno v:
The Journal of Experimental Medicine
The above experiments indicate that the growth-stimulating substance found in embryonic tissue extract, which has been responsible for the continuous growth of fibroblasts in vitro for 14 years, is either protein in nature or closely associated with
Autor:
Lillian E. Baker, Alexis Carrel
Publikováno v:
The Journal of Experimental Medicine
1. Fibroblasts and epithelial cells in pure culture obtain the nitrogen, which they build into protoplasm, from proteoses and possibly other primary derivatives of proteins. These proteoses have been prepared from embryo tissues, egg white, commercia
Autor:
Lillian E. Baker
Publikováno v:
The Journal of Experimental Medicine
1. It has been shown that the ash of liver, hemoglobin, and glutathione each exerts a very slight beneficial effect on the growth of sarcomatous fibroblasts of the rat, or on the condition of their cells when cultivated in a synthetic medium. 2. The
Autor:
Lillian E. Baker, Alexis Carrel
Publikováno v:
The Journal of Experimental Medicine
1. Both normal and sarcomatous fibroblasts of the rat utilize many different fragments of the protein molecule for their growth in vitro. Alpha and beta proteoses have approximately equal growth-promoting power. 2. A mixture of peptones, peptides, an
Autor:
Lillian E. Baker
Publikováno v:
Journal of Biological Chemistry. 193:809-819
Autor:
Lillian E. Baker, Alexis Carrel
Publikováno v:
The Journal of Experimental Medicine
The growth-inhibiting action of serum has been shown to be due largely to the lipoids. Serum from which the lipoids have been removed is much less inhibiting to the growth of fibroblasts in vitro than is the original serum, and only slightly more inh
Autor:
Robert B. Corey, Lillian E. Baker
Publikováno v:
The Journal of Experimental Medicine
The effects of cathode rays on the proteins of serum appear to be (1) denaturation of a large proportion of the albumin and globulin with the formation of products that are soluble at the pH of the serum; (2) the production of a tough and exceedingly