Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Lillian B, Cohn"'
Autor:
Daniel B. Reeves, Christian Gaebler, Thiago Y. Oliveira, Michael J. Peluso, Joshua T. Schiffer, Lillian B. Cohn, Steven G. Deeks, Michel C. Nussenzweig
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Most proviruses persisting in people living with HIV (PWH) on antiretroviral therapy (ART) are defective. However, rarer intact proviruses almost always reinitiate viral rebound if ART stops. Therefore, assessing therapies to prevent viral r
Externí odkaz:
https://doaj.org/article/5410e1dcab804b7b8a29c5381874026d
Autor:
Emily D Crawford, Irene Acosta, Vida Ahyong, Erika C Anderson, Shaun Arevalo, Daniel Asarnow, Shannon Axelrod, Patrick Ayscue, Camillia S Azimi, Caleigh M Azumaya, Stefanie Bachl, Iris Bachmutsky, Aparna Bhaduri, Jeremy Bancroft Brown, Joshua Batson, Astrid Behnert, Ryan M Boileau, Saumya R Bollam, Alain R Bonny, David Booth, Michael Jerico B Borja, David Brown, Bryan Buie, Cassandra E Burnett, Lauren E Byrnes, Katelyn A Cabral, Joana P Cabrera, Saharai Caldera, Gabriela Canales, Gloria R Castañeda, Agnes Protacio Chan, Christopher R Chang, Arthur Charles-Orszag, Carly Cheung, Unseng Chio, Eric D Chow, Y Rose Citron, Allison Cohen, Lillian B Cohn, Charles Chiu, Mitchel A Cole, Daniel N Conrad, Angela Constantino, Andrew Cote, Tre'Jon Crayton-Hall, Spyros Darmanis, Angela M Detweiler, Rebekah L Dial, Shen Dong, Elias M Duarte, David Dynerman, Rebecca Egger, Alison Fanton, Stacey M Frumm, Becky Xu Hua Fu, Valentina E Garcia, Julie Garcia, Christina Gladkova, Miriam Goldman, Rafael Gomez-Sjoberg, M Grace Gordon, James C R Grove, Shweta Gupta, Alexis Haddjeri-Hopkins, Pierce Hadley, John Haliburton, Samantha L Hao, George Hartoularos, Nadia Herrera, Melissa Hilberg, Kit Ying E Ho, Nicholas Hoppe, Shayan Hosseinzadeh, Conor J Howard, Jeffrey A Hussmann, Elizabeth Hwang, Danielle Ingebrigtsen, Julia R Jackson, Ziad M Jowhar, Danielle Kain, James Y S Kim, Amy Kistler, Oriana Kreutzfeld, Jessie Kulsuptrakul, Andrew F Kung, Charles Langelier, Matthew T Laurie, Lena Lee, Kun Leng, Kristoffer E Leon, Manuel D Leonetti, Sophia R Levan, Sam Li, Aileen W Li, Jamin Liu, Heidi S Lubin, Amy Lyden, Jennifer Mann, Sabrina Mann, Gorica Margulis, Diana M Marquez, Bryan P Marsh, Calla Martyn, Elizabeth E McCarthy, Aaron McGeever, Alexander F Merriman, Lauren K Meyer, Steve Miller, Megan K Moore, Cody T Mowery, Tanzila Mukhtar, Lusajo L Mwakibete, Noelle Narez, Norma F Neff, Lindsay A Osso, Diter Oviedo, Suping Peng, Maira Phelps, Kiet Phong, Peter Picard, Lindsey M Pieper, Neha Pincha, Angela Oliveira Pisco, Angela Pogson, Sergei Pourmal, Robert R Puccinelli, Andreas S Puschnik, Elze Rackaityte, Preethi Raghavan, Madhura Raghavan, James Reese, Joseph M Replogle, Hanna Retallack, Helen Reyes, Donald Rose, Marci F Rosenberg, Estella Sanchez-Guerrero, Sydney M Sattler, Laura Savy, Stephanie K See, Kristin K Sellers, Paula Hayakawa Serpa, Maureen Sheehy, Jonathan Sheu, Sukrit Silas, Jessica A Streithorst, Jack Strickland, Doug Stryke, Sara Sunshine, Peter Suslow, Renaldo Sutanto, Serena Tamura, Michelle Tan, Jiongyi Tan, Alice Tang, Cristina M Tato, Jack C Taylor, Iliana Tenvooren, Erin M Thompson, Edward C Thornborrow, Eric Tse, Tony Tung, Marc L Turner, Victoria S Turner, Rigney E Turnham, Mary J Turocy, Trisha V Vaidyanathan, Ilia D Vainchtein, Manu Vanaerschot, Sara E Vazquez, Anica M Wandler, Anne Wapniarski, James T Webber, Zara Y Weinberg, Alexandra Westbrook, Allison W Wong, Emily Wong, Gajus Worthington, Fang Xie, Albert Xu, Terrina Yamamoto, Ying Yang, Fauna Yarza, Yefim Zaltsman, Tina Zheng, Joseph L DeRisi
Publikováno v:
PLoS Pathogens, Vol 16, Iss 10, p e1008966 (2020)
Externí odkaz:
https://doaj.org/article/3bbb68a359bd42bc9db996dc6d89e140
Autor:
Emilie Battivelli, Matthew S Dahabieh, Mohamed Abdel-Mohsen, J Peter Svensson, Israel Tojal Da Silva, Lillian B Cohn, Andrea Gramatica, Steven Deeks, Warner C Greene, Satish K Pillai, Eric Verdin
Publikováno v:
eLife, Vol 7 (2018)
Human immunodeficiency virus (HIV) infection is currently incurable, due to the persistence of latently infected cells. The ‘shock and kill’ approach to a cure proposes to eliminate this reservoir via transcriptional activation of latent provirus
Externí odkaz:
https://doaj.org/article/8b9107104fa34f28952b121baac83f0f
Autor:
Georg H J, Weymar, Yotam, Bar-On, Thiago Y, Oliveira, Christian, Gaebler, Victor, Ramos, Harald, Hartweger, Gaëlle, Breton, Marina, Caskey, Lillian B, Cohn, Mila, Jankovic, Michel C, Nussenzweig
Publikováno v:
Cell reports. 40(10)
Antiretroviral therapy controls, but does not cure, HIV-1 infection due to a reservoir of rare CD4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2590a1657cb98e497b0e0bc7468f43de
https://pubmed.ncbi.nlm.nih.gov/36070690
https://pubmed.ncbi.nlm.nih.gov/36070690
Autor:
Georg H J Weymar, Yotam Bar-On, Thiago Y. Oliveira, Christian Gaebler, Victor Ramos, Harald Hartweger, Gaëlle Breton, Marina Caskey, Lillian B Cohn, Mila Jankovic, Michel C Nussenzweig
SummaryAntiretroviral therapy controls but does not cure HIV-1 infection due to a reservoir of rare CD4+ T cells harboring latent proviruses. Little is known about the transcriptional program of latent cells. Here we report a novel strategy to enrich
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::905f955832db2641531a6a2f06d0f2be
https://doi.org/10.1101/2022.03.02.482683
https://doi.org/10.1101/2022.03.02.482683
Autor:
Lillian B Cohn, Amy S. Huang, Michel C. Nussenzweig, Thiago Y. Oliveira, Mila Jankovic, Christian Gaebler, Victor A. Ramos
Publikováno v:
The Journal of Experimental Medicine
This study combines HIV-1 sequence analysis and integration site discovery to show a preponderance of integrations into ZNF genes in expanded latent clones. ZNF genes, unlike other integration targets, are downregulated upon T cell activation, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::394c2f70d3a33138fff1609c92b4bfd5
https://pubmed.ncbi.nlm.nih.gov/34636876
https://pubmed.ncbi.nlm.nih.gov/34636876
Autor:
Becky Xu Hua Fu, Erin M. Thompson, Agnes Protacio Chan, Zara Y. Weinberg, Alain R Bonny, Samantha Hao, Nicholas Hoppe, Aparna Bhaduri, Angela Constantino, Fauna Yarza, Suping Peng, Lillian B. Cohn, Gajus Worthington, Paula Hayakawa Serpa, Diana M. Marquez, Rafael Gomez-Sjoberg, Saharai Caldera, Norma Neff, Neha Pincha, Peter Picard, Andrew Cote, Diter Oviedo, Shayan Hosseinzadeh, Robert Puccinelli, Danielle Ingebrigtsen, Serena Tamura, Sergei Pourmal, Jeffrey A. Hussmann, Anica M. Wandler, M. Grace Gordon, Irene Acosta, Shweta Gupta, Jeremy Bancroft Brown, Joseph L. DeRisi, Shannon Axelrod, Andreas S. Puschnik, Lindsey M. Pieper, Joseph M. Replogle, Valentina E. Garcia, James Reese, Patrick Ayscue, Arthur Charles-Orszag, Iliana Tenvooren, Eric Tse, Alison Fanton, Elze Rackaityte, Charles Y. Chiu, Aileen W. Li, Edward Thornborrow, Amy Lyden, Katelyn A. Cabral, Sukrit Silas, Kun Leng, Erika Anderson, Lusajo L. Mwakibete, Shaun Arevalo, Gabriela Canales, Calla Martyn, Gorica Margulis, Andrew F. Kung, Sophia R. Levan, Tanzila Mukhtar, Carly K. Cheung, Jonathan Sheu, Sam Li, Charles Langelier, Gloria Castaneda, Tina Zheng, Maureen Sheehy, Rebecca Egger, Amy Kistler, Alexander F. Merriman, Sara Sunshine, Cody T. Mowery, Madhura Raghavan, Allison Cohen, Terrina Yamamoto, Mitchel A. Cole, Saumya R. Bollam, Megan Moore, Preethi Raghavan, Jessie Kulsuptrakul, Stacey M. Frumm, Manu Vanaerschot, Fang Xie, Daniel Asarnow, Miriam Goldman, Pierce Hadley, Sara E. Vazquez, Michelle Tan, Kristin K. Sellers, Lindsay A. Osso, Lauren K. Meyer, Daniel N. Conrad, Sabrina A Mann, Vida Ahyong, Kristoffer E. Leon, Un Seng Chio, Camillia S. Azimi, Bryan Marsh, Anne E. Wapniarski, Stefanie Bachl, Kit Ying E. Ho, Rigney E. Turnham, Aaron McGeever, Cassandra E. Burnett, Rebekah Dial, Caleigh M. Azumaya, Helen Reyes, Victoria S. Turner, Jiongyi Tan, Emily D. Crawford, Allison W. Wong, Spyros Darmanis, Shen Dong, Lena Lee, Y. Rose Citron, Christopher R. Chang, Astrid Behnert, Ziad M. Jowhar, Nadia Herrera, Doug Stryke, Lauren Byrnes, Albert Xu, James C. R. Grove, Cristina M. Tato, George C. Hartoularos, Tony Tung, Iris Bachmutsky, Ryan M. Boileau, Peter Suslow, Jessica Streithorst, Alexis Haddjeri-Hopkins, John R. Haliburton, Conor J Howard, Angela Oliveira Pisco, Eric D. Chow, Elizabeth E. McCarthy, Joshua Batson, Oriana Kreutzfeld, Elizabeth Hwang, Hanna Retallack, Danielle Kain, Alice Tang, Jack C. Taylor, Emily C. Wong, Donald Rose, Julia R. Jackson, Alexandra Westbrook, Matthew T. Laurie, Jennifer Mann, Renaldo Sutanto, Mary J. Turocy, Trisha V. Vaidyanathan, Melissa Hilberg, Stephanie K. See, David S. Booth, Christina Gladkova, Jack Strickland, Julie M. Garcia, Marc L. Turner, David Dynerman, Manuel D. Leonetti, Laura Savy, Noelle Narez, Jamin Liu, Ilia D. Vainchtein, Ying Yang, Kiet T. Phong, Tre’Jon Crayton-Hall, David Brown, Marci F. Rosenberg, Bryan Buie, Maira Phelps, Sydney M. Sattler, Elias Duarte, Yefim Zaltsman, Angela M. Detweiler, Estella Sanchez-Guerrero, Joana P. Cabrera, Michael Jerico B. Borja, James Y. S. Kim, Heidi S. Lubin, Angela Pogson, Steve Miller, James T. Webber
Publikováno v:
PLoS Pathogens, Vol 16, Iss 10, p e1008966 (2020)
PLoS Pathogens
PLoS Pathogens
Author(s): Crawford, Emily D; Acosta, Irene; Ahyong, Vida; Anderson, Erika C; Arevalo, Shaun; Asarnow, Daniel; Axelrod, Shannon; Ayscue, Patrick; Azimi, Camillia S; Azumaya, Caleigh M; Bachl, Stefanie; Bachmutsky, Iris; Bhaduri, Aparna; Brown, Jeremy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90f769d674844a50804f8ecde46fb4c3
https://doaj.org/article/3bbb68a359bd42bc9db996dc6d89e140
https://doaj.org/article/3bbb68a359bd42bc9db996dc6d89e140
Autor:
Lillian B. Cohn, Steven G. Deeks
Publikováno v:
The Journal of clinical investigation, vol 130, iss 6
J Clin Invest
J Clin Invest
Plasmacytoid dendritic cells (pDCs) are robust producers of IFNα and one of the first immune cells to respond to SIV infection. To elucidate responses to early HIV-1 replication, we studied blood pDCs in 29 HIV-infected participants who initiated an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73d13b8ca0b7e45a7a6de8ab2f600f05
https://escholarship.org/uc/item/9208z3f0
https://escholarship.org/uc/item/9208z3f0
Autor:
Pilar Mendoza, Christian Gaebler, Marina Caskey, Mila Jankovic, Julia R. Jackson, Victor A. Ramos, Lillian B. Cohn, Thiago Y. Oliveira, Michel C. Nussenzweig
Publikováno v:
The Journal of Experimental Medicine
Mendoza et al. identify clones of HIV-1 defective or intact latent proviruses within antigen-responsive CD4+ T cells. This study suggests that exposure to chronic or recurrent antigens may contribute to reservoir persistence by stimulating the clonal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2f62a7e3f0cb36093182940cf3ac833
https://doi.org/10.1084/jem.20200051
https://doi.org/10.1084/jem.20200051
Autor:
Lillian B. Cohn, Julia R. Jackson, Mila Jankovic, Victor A. Ramos, Pilar Mendoza, Marina Caskey, Michel C. Nussenzweig, Christian Gaebler, Thiago Y. Oliveira
Antiretroviral therapy suppresses but does not cure HIV-1 infection due to the existence of a long-lived reservoir of latently infected cells. The reservoir has an estimated half-life of 44 months and is largely composed of clones of infected CD4+ T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ed2cc04f759bc73515a91b3d2f0bc82