Výsledky vyhledávání - "Lillia Hadjem"

Abstract 4630: Deep Immuno-profiling of syngeneic tumor mouse models for preclinical studies

Autor: Anais Joachim, Emilie Maturin, Marielle Mello, Lillia Hadjem, Magali Grange, Olivier Deas, Ana Zarubica, Bernard Malissen, Hervé Luche

Publikováno v: Cancer Research. 83:4630-4630

Identification of major cellular players involved in progression of cancer is key to success of new immunotherapies. It is however a daunting challenge due to the complex interplay between tumor cells and the immune system. Component of innate and ad

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7dabe736ad7edc639991ad307e3cc68a
https://doi.org/10.1158/1538-7445.am2023-4630

Zobrazit plný text záznamu

Abstract 5190: Systematic immune-profiling of immune-deficient mouse models: A rational to select ideal host for tumor implantation

Autor: Hervé Luche, Lillia Hadjem, Marielle Mello, Priscilla Canavese, Fabien Angelis, Anais Joachim, Sylvie Bouilly, Frederic Guinut, Frederic Fiore, Bernard Malissen, Ana Zarubica, Erwan Corcuff

Publikováno v: Cancer Research. 83:5190-5190

Preclinical tumor oncology research relies historically on the analysis of mouse or human tumor cell lines implanted onto severely immune-deficient mouse models carrying nude, SCID or Rag mutations on different genetical background (C57Bl/6N, BalbC,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::470e4d6f526c0152c85df0beb54c7e32
https://doi.org/10.1158/1538-7445.am2023-5190

Zobrazit plný text záznamu

Serine Phosphorylation of SLP76 Is Dispensable for T Cell Development but Modulates Helper T Cell Function

Autor: Navas, Victor H, Cuche, Céline, Alcover, Andres, Di Bartolo, Vincenzo

Publikováno v: PLoS ONE
PLoS ONE, Vol 12, Iss 1, p e0170396 (2017)
PLoS ONE, 2017, 12 (1), pp.e0170396. ⟨10.1371/journal.pone.0170396⟩
PLoS ONE, Public Library of Science, 2017, 12 (1), pp.e0170396. ⟨10.1371/journal.pone.0170396⟩

International audience; The adapter protein SLP76 is a key orchestrator of T cell receptor (TCR) signal transduction. We previously identified a negative feedback loop that modulates T cell activation, involving phosphorylation of Ser376 of SLP76 by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::149feb0499b077f182147d84dd2bc1af
https://pubmed.ncbi.nlm.nih.gov/28107427

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání