Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Lillia, Ryazanova"'
Autor:
Francisco J. Rios, Zhi-Guo Zou, Adam P. Harvey, Katie Y. Harvey, Livia L. Camargo, Karla B. Neves, Sarah E. F. Nichol, Rheure Alves-Lopes, Alexius Cheah, Maram Zahraa, Alexey G. Ryazanov, Lillia Ryazanova, Thomas Gudermann, Vladimir Chubanov, Augusto C. Montezano, Rhian M. Touyz
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
Deficiency of the Mg2+-permeable channel/α-kinase TRPM7 in mice increases susceptibility to cardiovascular and renal fibrosis induced by aldosterone and salt.
Externí odkaz:
https://doaj.org/article/cb2321b1b4554eefad7adf3bec82bdc7
Autor:
Francisco J, Rios, Zhi-Guo, Zou, Adam P, Harvey, Katie Y, Harvey, Ryszard, Nosalski, Panagiota, Anyfanti, Livia L, Camargo, Silvia, Lacchini, Alexey G, Ryazanov, Lillia, Ryazanova, Sarah, McGrath, Tomasz J, Guzik, Carl S, Goodyear, Augusto C, Montezano, Rhian M, Touyz
Publikováno v:
Cardiovascular research. 116(3)
Transient Receptor Potential Melastatin 7 (TRPM7) cation channel is a chanzyme (channel + kinase) that influences cellular Mg2+ homeostasis and vascular signalling. However, the pathophysiological significance of TRPM7 in the cardiovascular system is
Publikováno v:
The Journal of Immunology. 184:86.14-86.14
TRPM7 is a bi-functional protein where an ion channel domain is fused with an atypical α-kinase domain. Impairment of the kinase domain leads to hypomagnesemia and sensitization to allergic reactions. We here investigate whether TRPM7 is involved in