Interplay Between Duration of Androgen Deprivation Therapy and External Beam Radiotherapy With or Without a Brachytherapy Boost for Optimal Treatment of High-risk Prostate Cancer: A Patient-Level Data Analysis of 3 Cohorts.

Autor: Kishan AU; Department of Radiation Oncology, University of California, Los Angeles.; Department of Urology, University of California, Los Angeles., Steigler A; School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia., Denham JW; School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia., Zapatero A; Hospital Universitario de la Princesa, Madrid, Spain., Guerrero A; Hospital Son Espases, Palma de Mallorca, Spain., Joseph D; Sir Charles Gairdner Hospital, Perth, West Australia, Australia.; Department of Medicine and Surgery, University of Western Australia, Perth, West Australia, Australia., Maldonado X; Hospital Universitari Vall d'Hebron, Barcelona, Spain., Wong JK; Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Stish BJ; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota., Dess RT; Department of Radiation Oncology, University of Michigan, Ann Arbor., Pilar A; Radiation Medicine Program, Princess Margaret Cancer Centre, Toronto, Ontario, Canada.; Department of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada., Reddy C; Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio., Wedde TB; Oslo University Hospital, Oslo, Norway., Lilleby WA; Oslo University Hospital, Oslo, Norway., Fiano R; Schiffler Cancer Center, Wheeling Hospital, Wheeling Jesuit University, Wheeling, West Virginia., Merrick GS; Schiffler Cancer Center, Wheeling Hospital, Wheeling Jesuit University, Wheeling, West Virginia., Stock RG; Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, New York, New York., Demanes DJ; Department of Radiation Oncology, University of California, Los Angeles.; California Endocurietherapy Cancer Center, Oakland., Moran BJ; Chicago Prostate Cancer Center, Westmont, Illinois., Tran PT; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland., Martin S; Department of Radiation Oncology, Program in Solid Tumors, Clínica Universidad de Navarra, Pamplona, Spain., Martinez-Monge R; Department of Radiation Oncology, Program in Solid Tumors, Clínica Universidad de Navarra, Pamplona, Spain., Krauss DJ; William Beaumont School of Medicine, Oakland University, Royal Oak, Michigan., Abu-Isa EI; Department of Radiation Oncology, University of Michigan, Ann Arbor., Pisansky TM; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota., Choo CR; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota., Song DY; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland., Greco S; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland., Deville C; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland., McNutt T; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland., DeWeese TL; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland., Ross AE; Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois., Ciezki JP; Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio., Tilki D; Department of Urology, University Hospital Hamburg-Eppendorf, Hamburg, Germany.; Martini-Klinik Prostate Cancer Center, University Hospital Hamburg-Eppendorf, Hamburg, Germany., Karnes RJ; Department of Urology, Mayo Clinic, Rochester, Minnesota., Tosoian JJ; Department of Urology, The James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland., Nickols NG; Department of Radiation Oncology, University of California, Los Angeles.; Department of Radiation Oncology, West Los Angeles Veterans Health Administration, Los Angeles, California., Bhat P; David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California., Shabsovich D; David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California., Juarez JE; David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California., Jiang T; Department of Radiation Oncology, University of California, Los Angeles., Ma TM; Department of Radiation Oncology, University of California, Los Angeles., Xiang M; Department of Radiation Oncology, University of California, Los Angeles., Philipson R; Department of Radiation Oncology, University of California, Los Angeles., Chang A; Department of Radiation Oncology, University of California, Los Angeles., Kupelian PA; Department of Radiation Oncology, University of California, Los Angeles., Rettig MB; Division of Medical Oncology, Ronald Reagan UCLA Medical Center, University of California, Los Angeles.; Department of Medical Oncology, West Los Angeles Veterans Health Administration, Los Angeles, California., Feng FY; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco., Berlin A; Radiation Medicine Program, Princess Margaret Cancer Centre, Toronto, Ontario, Canada., Tward JD; Department of Radiotherapy Oncology, Huntsman Cancer Institute at the University of Utah, Salt Lake City., Davis BJ; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota., Reiter RE; Department of Urology, University of California, Los Angeles., Steinberg ML; Department of Radiation Oncology, University of California, Los Angeles., Elashoff D; Division of General Internal Medicine and Health Services Research, University of California, Los Angeles., Boutros PC; Department of Urology, University of California, Los Angeles.; Department of Human Genetics, University of California, Los Angeles., Horwitz EM; Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Tendulkar RD; Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio., Spratt DE; Seidman Cancer Center, Case Western Reserve University, Cleveland, Ohio., Romero T; Division of General Internal Medicine and Health Services Research, University of California, Los Angeles.

Publikováno v: JAMA oncology [JAMA Oncol] 2022 Mar 01; Vol. 8 (3), pp. e216871. Date of Electronic Publication: 2022 Mar 17.

Performance of a Prostate-Specific Membrane Antigen Positron Emission Tomography/Computed Tomography-Derived Risk-Stratification Tool for High-risk and Very High-risk Prostate Cancer.

Autor: Xiang M; Department of Radiation Oncology, University of California, Los Angeles., Ma TM; Department of Radiation Oncology, University of California, Los Angeles., Savjani R; Department of Radiation Oncology, University of California, Los Angeles., Pollom EL; Department of Radiation Oncology, Stanford University, Stanford, California., Karnes RJ; Department of Urology, Mayo Clinic, Rochester, Minnesota., Grogan T; Department of Medicine Statistics Core, David Geffen School of Medicine at UCLA, Los Angeles, California., Wong JK; Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Motterle G; Department of Urology, Mayo Clinic, Rochester, Minnesota., Tosoian JJ; Department of Urology, University of Michigan, Ann Arbor., Trock BJ; Department of Urology, Brady Urological Institute, Johns Hopkins University, Baltimore, Maryland., Klein EA; Department of Urology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio., Stish BJ; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota., Dess RT; Department of Radiation Oncology, University of Michigan, Ann Arbor., Spratt DE; Department of Radiation Oncology, University of Michigan, Ann Arbor., Pilar A; Department of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada., Reddy C; Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio., Levin-Epstein R; Department of Radiation Oncology, University of California, Los Angeles., Wedde TB; Department of Oncology, Oslo University Hospital, Norwegian Radium Hospital, Oslo, Norway., Lilleby WA; Department of Oncology, Oslo University Hospital, Norwegian Radium Hospital, Oslo, Norway., Fiano R; Schiffler Cancer Center, Wheeling Hospital, Wheeling Jesuit University, Wheeling, West Virginia., Merrick GS; Schiffler Cancer Center, Wheeling Hospital, Wheeling Jesuit University, Wheeling, West Virginia., Stock RG; Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, New York City, New York., Demanes DJ; Department of Radiation Oncology, University of California, Los Angeles., Moran BJ; Prostate Cancer Foundation of Chicago, Westmont, Illinois., Huland H; Martini-Klinik Prostate Cancer Center, University Hospital Hamburg Eppendorf, Hamburg, Germany., Tran PT; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland., Martin S; Department of Oncology, Clínica Universitaria de Navarra, University of Navarra, Pamplona, Spain., Martinez-Monge R; Department of Oncology, Clínica Universitaria de Navarra, University of Navarra, Pamplona, Spain., Krauss DJ; Oakland University William Beaumont School of Medicine, Royal Oak, Michigan., Abu-Isa EI; Department of Radiation Oncology, University of Michigan, Ann Arbor., Alam R; Department of Urology, Brady Urological Institute, Johns Hopkins University, Baltimore, Maryland., Schwen Z; Department of Urology, Brady Urological Institute, Johns Hopkins University, Baltimore, Maryland., Pisansky TM; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota., Choo CR; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota., Song DY; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland., Greco S; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland., Deville C; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland., McNutt T; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland., DeWeese TL; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland., Ross AE; Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, Illinois., Ciezki JP; Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio., Boutros PC; Department of Human Genetics, University of California, Los Angeles., Nickols NG; Department of Radiation Oncology, University of California, Los Angeles.; Department of Radiation Oncology, Veterans Affairs (VA) Greater Los Angeles Healthcare System, Los Angeles, California., Bhat P; Department of Radiation Oncology, University of California, Los Angeles., Shabsovich D; Department of Radiation Oncology, University of California, Los Angeles., Juarez JE; Department of Radiation Oncology, University of California, Los Angeles., Chong N; Department of Radiation Oncology, University of California, Los Angeles., Kupelian PA; Department of Radiation Oncology, University of California, Los Angeles., Rettig MB; Division of Hematology and Oncology, Department of Medicine, University of California, Los Angeles.; Department of Hematology and Oncology, Veterans Affairs (VA) Greater Los Angeles Healthcare System, Los Angeles, California., Zaorsky NG; Department of Radiation Oncology, Penn State Cancer Institute, Hershey, Pennsylvania., Berlin A; Department of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada., Tward JD; Department of Radiation Oncology, Huntsman Cancer Institute, University of Utah, Salt Lake City., Davis BJ; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota., Reiter RE; Department of Urology, University of California, Los Angeles., Steinberg ML; Department of Radiation Oncology, University of California, Los Angeles., Elashoff D; Department of Medicine Statistics Core, David Geffen School of Medicine at UCLA, Los Angeles, California., Horwitz EM; Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Tendulkar RD; Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio., Tilki D; Martini-Klinik Prostate Cancer Center, University Hospital Hamburg Eppendorf, Hamburg, Germany.; Department of Urology, University Hospital Hamburg-Eppendorf, Hamburg, Germany., Czernin J; Ahmanson Translational Theranostics Division, Department of Molecular and Medical Pharmacology, UCLA Medical Center, Los Angeles, California., Gafita A; Ahmanson Translational Theranostics Division, Department of Molecular and Medical Pharmacology, UCLA Medical Center, Los Angeles, California., Romero T; Department of Medicine Statistics Core, David Geffen School of Medicine at UCLA, Los Angeles, California., Calais J; Ahmanson Translational Theranostics Division, Department of Molecular and Medical Pharmacology, UCLA Medical Center, Los Angeles, California., Kishan AU; Department of Radiation Oncology, University of California, Los Angeles.

Publikováno v: JAMA network open [JAMA Netw Open] 2021 Dec 01; Vol. 4 (12), pp. e2138550. Date of Electronic Publication: 2021 Dec 01.

Comparison of Multimodal Therapies and Outcomes Among Patients With High-Risk Prostate Cancer With Adverse Clinicopathologic Features.

Autor: Kishan AU; Department of Radiation Oncology, University of California, Los Angeles.; Department of Urology, University of California, Los Angeles., Karnes RJ; Department of Urology, Mayo Clinic, Rochester, Minnesota., Romero T; Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Wong JK; Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Motterle G; Department of Urology, Mayo Clinic, Rochester, Minnesota., Tosoian JJ; Department of Urology, University of Michigan, Ann Arbor., Trock BJ; Department of Urology, Brady Urological Institute, Johns Hopkins University, Baltimore, Maryland., Klein EA; Department of Urology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio., Stish BJ; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota., Dess RT; Department of Radiation Oncology, University of Michigan, Ann Arbor., Spratt DE; Department of Radiation Oncology, University of Michigan, Ann Arbor., Pilar A; Department of Radiation Oncology, University of Toronto, Toronto, Canada., Reddy C; Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio., Levin-Epstein R; Department of Radiation Oncology, University of California, Los Angeles., Wedde TB; Department of Oncology, Oslo University Hospital, The Norwegian Radium Hospital, Oslo, Norway., Lilleby WA; Department of Oncology, Oslo University Hospital, The Norwegian Radium Hospital, Oslo, Norway., Fiano R; Schiffler Cancer Center, Wheeling Hospital, Wheeling Jesuit University, Wheeling, West Virginia., Merrick GS; Schiffler Cancer Center, Wheeling Hospital, Wheeling Jesuit University, Wheeling, West Virginia., Stock RG; Radiation Oncology, Icahn School of Medicine at Mount Sinai, New York, New York., Demanes DJ; Department of Radiation Oncology, University of California, Los Angeles., Moran BJ; Prostate Cancer Foundation of Chicago, Westmont, Illinois., Braccioforte M; Prostate Cancer Foundation of Chicago, Westmont, Illinois., Huland H; Martini-Klinik Prostate Cancer Center, University Hospital Hamburg Eppendorf, Hamburg, Germany., Tran PT; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland., Martin S; Department of Oncology, Clínica Universitaria de Navarra, University of Navarra, Pamplona, Spain., Martínez-Monge R; William Beaumont School of Medicine, Oakland University, Royal Oak, Michigan., Krauss DJ; William Beaumont School of Medicine, Oakland University, Royal Oak, Michigan., Abu-Isa EI; Department of Radiation Oncology, University of Michigan, Ann Arbor., Alam R; Department of Urology, Brady Urological Institute, Johns Hopkins University, Baltimore, Maryland., Schwen Z; Department of Urology, Brady Urological Institute, Johns Hopkins University, Baltimore, Maryland., Chang AJ; Department of Radiation Oncology, University of California, Los Angeles., Pisansky TM; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota., Choo R; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota., Song DY; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland., Greco S; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland., Deville C; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland., McNutt T; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland., DeWeese TL; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland., Ross AE; Texas Oncology, Dallas.; Now with Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, Illinois., Ciezki JP; Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio., Boutros PC; Department of Urology, University of California, Los Angeles.; Department of Human Genetics, University of California, Los Angeles., Nickols NG; Department of Radiation Oncology, University of California, Los Angeles.; Department of Radiation Oncology, VA Greater Los Angeles Healthcare System, Los Angeles, California., Bhat P; Department of Radiation Oncology, University of California, Los Angeles., Shabsovich D; Department of Radiation Oncology, University of California, Los Angeles., Juarez JE; Department of Radiation Oncology, University of California, Los Angeles., Chong N; Department of Radiation Oncology, University of California, Los Angeles., Kupelian PA; Department of Radiation Oncology, University of California, Los Angeles., D'Amico AV; Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston, Massachusetts., Rettig MB; Division of Hematology and Oncology, Department of Medicine, University of California, Los Angeles.; Department of Hematology and Oncology, VA Greater Los Angeles Healthcare System, Los Angeles, California., Berlin A; Department of Radiation Oncology, University of Toronto, Toronto, Canada., Tward JD; Department of Radiation Oncology, Huntsman Cancer Institute, The University of Utah, Salt Lake City., Davis BJ; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota., Reiter RE; Department of Urology, University of California, Los Angeles., Steinberg ML; Department of Radiation Oncology, University of California, Los Angeles., Elashoff D; Department of Medicine Statistics Core, David Geffen School of Medicine, University of California, Los Angeles., Horwitz EM; Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Tendulkar RD; Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio., Tilki D; Martini-Klinik Prostate Cancer Center, University Hospital Hamburg Eppendorf, Hamburg, Germany.; Department of Urology, University Hospital Hamburg-Eppendorf, Hamburg, Germany.

Publikováno v: JAMA network open [JAMA Netw Open] 2021 Jul 01; Vol. 4 (7), pp. e2115312. Date of Electronic Publication: 2021 Jul 01.