Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Lilla Landeck"'
Autor:
Bing-Xi Yan, Xue-Yan Chen, Zhao-Yuan Wang, Ying-Zhe Cui, Lilla Landeck, Ni-Chang Fu, Xing-Yu Yang, Fan Xu, Yuan Zhou, Jia-Qi Chen, Xiao-Yong Man
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-14 (2022)
Abstract Background The Isoleucyl-tRNA synthetase (IARS) catalyzes isoleucine to the corresponding tRNA, maintaining the accuracy of gene translation. Its role in psoriasis has been not investigated so far. In this study, we aimed to investigate the
Externí odkaz:
https://doaj.org/article/92baaf494c884de2bf985d78e9e4594b
Autor:
Yuan Zhou, Ping Wang, Bing-Xi Yan, Xue-Yan Chen, Lilla Landeck, Zhao-Yuan Wang, Xin-Xin Li, Jing Zhang, Min Zheng, Xiao-Yong Man
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Psoriasis is a common chronic inflammatory systemic disease. Epidermal proteins are considered to be important in maintaining skin barrier function, innate immunity, and inflammation. To define more possible roles of the epidermis in the pathogenesis
Externí odkaz:
https://doaj.org/article/0d5c4cb2f83b402ea926d47728a749fe
Autor:
Min Min, Xi-Bei Chen, Ping Wang, Lilla Landeck, Jia-Qi Chen, Wei Li, Sui-Qing Cai, Min Zheng, Xiao-Yong Man
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0174626 (2017)
Keratin 24 (K24) is a new kind of keratin genes, which encodes a novel keratin protein, K24 that bears high similarity to the type I keratins and displays a unique expression profile. However, the role of K24 is incompletely understood. In our study,
Externí odkaz:
https://doaj.org/article/6f071a7a8f51489c912b32fe6ef958fb
Autor:
Min Min, Bing-Xi Yan, Ping Wang, Lilla Landeck, Jia-Qi Chen, Wei Li, Sui-Qing Cai, Min Zheng, Xiao-Yong Man
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0190051 (2017)
Rottlerin is a natural polyphenolic compound that was initially indicated as a PKCδ inhibitor. However, it was recently revealed that it may target a number of molecules and have biological effects on various cell types and is considered as a possib
Externí odkaz:
https://doaj.org/article/3245f89643d94b48b42930504564e075
Autor:
Xiao-Yong Man, Xi-Bei Chen, Wei Li, Lilla Landeck, Ting-Ting Dou, Jia-qi Chen, Jiong Zhou, Sui-Qing Cai, Min Zheng
Publikováno v:
Open Biology, Vol 5, Iss 8 (2015)
Psoriasis is similar to endpoints of epithelial–mesenchymal transition (EMT), a process of epithelial cells transformed into fibroblast-like cells. The molecular epithelial and mesenchymal markers were analysed in psoriatic keratinocytes. No obviou
Externí odkaz:
https://doaj.org/article/3b85089fa34441c3a979e69a2080ec58
Autor:
Matthias, Augustin, Lilla, Landeck, Sebastian, Diemert, Khusru, Asadullah, Urte, Hammann, Konstantin, Ertner, Ina, Hadshiew
Publikováno v:
Dermatology and Therapy. 12:1121-1131
Dimethyl fumarate (DMF) is an oral compound to treat plaque psoriasis. Data on the treatment of patients with psoriasis affecting impactful areas are scarce. In this interim analysis of the prospective, noninterventional SKILL study, we summarized re
Autor:
Yuan Zhou, Ping Wang, Xue‐Yan Chen, Bing‐Xi Yan, Lilla Landeck, Zhao‐Yuan Wang, Fan Xu, Min Zheng, Xiao‐Yong Man
Publikováno v:
Cell Proliferation. 55
Psoriasis is an immune-mediated skin disease dominated by the cutaneous immune system. Keratinocytes have been considered important triggers that initiate psoriasis. The key molecules and events of keratinocytes that link the innate immune system in
Autor:
Xue-Yan Chen, Fan Xu, Jia-Qi Chen, Lilla Landeck, Si-Qi Chen, Yuan Zhou, Zhaoyuan Wang, Ni-Chang Fu, Min Zheng, Xuzhao Zhang, Xiao-Yong Man
Publikováno v:
The Journal of investigative dermatology.
Proinflammatory cytokines, such as interleukin-1 beta (IL-1β), are important mediators of psoriasis. Ubiquitin conjugating enzyme E2 L3 (UBE2L3), an E2 enzyme, is thought to be an indirect target of IL-1β secretion by binding to ubiquitin ligases (
Autor:
Kamran Ghoreschi, Katja Fuhrmeister, Xiao Yong Man, Ernesto Gonzalez-Martinez, Robert Sabat, Khusru Asadullah, Lilla Landeck
Publikováno v:
Immunotherapy. 13(7)
Over the past two decades, significant progress has been achieved in the treatment of psoriasis by targeting the human cytokine network. At present, 11 biologicals – antibodies, and a soluble receptor – are used to neutralize key inflammatory cyt