Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Liling Niu"'
Autor:
Guangying Xu, Liling Niu, Youhui Wang, Guang Yang, Xingwu Zhu, Yuan Yao, Gang Zhao, Shaowei Wang, Hui Li
Publikováno v:
Cell Death and Disease, Vol 13, Iss 10, Pp 1-14 (2022)
Abstract Histone deacetylase 6 (HDAC6), a member of the HDAC family, has been identified as a potential therapeutic target for tumor therapy, but the function and underlying mechanisms of HDAC6 in colon cancer are incompletely characterized. Our stud
Externí odkaz:
https://doaj.org/article/43fe80332fbe4f0ab1ea4f270217c1ae
Autor:
Xin Chen, Hui Li, Yang Yang, Ping Li, Ping Liao, Yifei Wang, Mengmeng Jiang, Liling Niu, Yibo Chen, Jingbin Zheng, Fengyang Chen, Huanhuan He
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 11 (2022)
Background Tumor necrosis factor receptor type 2 (TNFR2) is primarily expressed by CD4+FoxP3+ regulatory T cells (Tregs), especially those present in tumor microenvironment. There is compelling evidence that TNFR2 plays a crucial role in the activati
Externí odkaz:
https://doaj.org/article/7cd12e0a6e33455894ee1799086402ee
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-11 (2021)
Abstract Circular RNAs (circRNAs) are a novel class of endogenous noncoding RNAs (ncRNAs) with a covalently closed loop structure. Accumulating evidence shows that circRNAs play vital roles in the growth, metastasis, treatment and prognosis of variou
Externí odkaz:
https://doaj.org/article/4441aaffd2304ebdab9fc4e6ac97fe76
Autor:
Xianzhuang Liu, Xiangyang Guo, Liling Niu, Xixia Li, Fei Sun, Junjie Hu, Xiangming Wang, Kang Shen
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
The molecular mechanisms that achieve ER morphology in neurites are not well understood. This study uses a forward genetic approach to demonstrate that atln-1 is required for neuronal ER morphology and that C. elegans atln-1 mutants exhibit defects i
Externí odkaz:
https://doaj.org/article/5fedf1bfc9bf4bae9dd14b5234f42558
Publikováno v:
Oncogene. 42:980-993
Circular RNA (circRNA) is a novel RNA molecule characterized by covalently closed loop structure. Since its discovery, researchers have shown that circRNA is not “splicing noise” but a participant of various pathophysiological processes through u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::800b9395b05996bfa11f5a0cd19d2a5d
https://doi.org/10.1038/s41388-023-02610-z
https://doi.org/10.1038/s41388-023-02610-z
Publikováno v:
International Journal of Cancer. 150:1373-1391
TNFR2+ regulatory T cells preferentially accumulate in the tumor microenvironment, express high levels of immunosuppressive molecules and possess strong suppressive activity. This study aimed to explore the characteristics and role of TNFR2+ Tregs in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9016bf2311587e97ee5679ef0e00ec6d
https://doi.org/10.1002/ijc.33873
https://doi.org/10.1002/ijc.33873
Autor:
Mengmeng Jiang, Yang Yang, Liling Niu, Ping Li, Yibo Chen, Ping Liao, Yifei Wang, Jingbin Zheng, Fengyang Chen, Huanhuan He, Hui Li, Xin Chen
Publikováno v:
Journal for immunotherapy of cancer. 10(11)
BackgroundTumor necrosis factor receptor type 2 (TNFR2) is primarily expressed by CD4+FoxP3+regulatory T cells (Tregs), especially those present in tumor microenvironment. There is compelling evidence that TNFR2 plays a crucial role in the activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dce46a3615f72fe997b8679d3f7129b6
https://pubmed.ncbi.nlm.nih.gov/36319063
https://pubmed.ncbi.nlm.nih.gov/36319063
Autor:
Yilin Deng, Jinjin Gao, Guangying Xu, Yuan Yao, Yan Sun, Yehui Shi, Xishan Hao, Liling Niu, Hui Li
Publikováno v:
Cancer letters. 549
Aberrant expression of histone deacetylase 6 (HDAC6) is greatly involved in neoplasm metastasis, which is a leading cause of colon cancer related death. Thus, deep understanding of the regulatory mechanisms of HDAC6 in the metastasis of colon cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da1a2309330069b7db129ea8b8d31a9c
https://pubmed.ncbi.nlm.nih.gov/36122629
https://pubmed.ncbi.nlm.nih.gov/36122629
Publikováno v:
Biophysics Reports. 6:105-114
In eukaryotic cells, the endoplasmic reticulum (ER) forms a continuous network of tubules and sheets. ER membranes are inter-connected by a class of dynamin-like GTPases termed atlastins (ATLs). Deletion or mutation of ATLs results in long and unbran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98c3792cc83d4ef2a7edb274d83a088e
https://doi.org/10.1007/s41048-020-00113-y
https://doi.org/10.1007/s41048-020-00113-y
Autor:
Feng Yang, Tianji Ma, Liling Niu, Bing Yan, Junjie Hu, Haidi Yin, Qian Wu, Jifeng Wang, Yan Huang, Xiao Tang, Zhongping Yao, Yusong Guo
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance In the early secretory pathway, newly synthesized proteins undergo folding and modifications and then leave the ER through COPII-coated vesicles. How these processes are coordinated and maintained are important but mostly unclear. We sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f4b7dc75f82bc590d1596910437d01f
https://doi.org/10.1073/pnas.1908409116
https://doi.org/10.1073/pnas.1908409116