Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Lilibeth Lanza"'
Autor:
Jennifer N. Rainho-Tomko, Vincent Pavot, Michael Kishko, Kurt Swanson, Darin Edwards, Heesik Yoon, Lilibeth Lanza, Judith Alamares-Sapuay, Robert Osei-Bonsu, Sophia T. Mundle, Dave A. Murison, Scott Gallichan, Simon Delagrave, Chih-Jen Wei, Linong Zhang, Gary J. Nabel
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-9 (2022)
Abstract Respiratory syncytial virus (RSV) G glycoprotein has recently reemerged as a vaccine antigen due to its ability to elicit potent neutralizing antibodies and ameliorate disease in animal models. Here we designed three constructs to display th
Externí odkaz:
https://doaj.org/article/ebfed4caf551425eb43d4a04f2b4e65f
Autor:
Sankalp Gupta, Zachary P. Williams, Darin K. Edwards, Linong Zhang, Scott Gallichan, Chih-Jen Wei, Haritha Adhikarla, Vincent Pavot, Jennifer N. Rainho-Tomko, Judith Alamares-Sapuay, Lilibeth Lanza, Gary J. Nabel, Michael Peredelchuk, Michael G. Kishko, Kurt Swanson, Sudha Chivukula, Heesik Yoon, Nicholas Jackson
Publikováno v:
Science immunology. 5(47)
A stabilized form of the respiratory syncytial virus (RSV) fusion (F) protein has been explored as a vaccine to prevent viral infection because it presents several potent neutralizing epitopes. Here, we used a structure-based rational design to optim