Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Liliane Tenenbaum"'
Autor:
Natalia Cecilia Prymaczok, Pablo Nicolas De Francesco, Samanta Mazzetti, Marie Humbert-Claude, Liliane Tenenbaum, Graziella Cappelletti, Eliezer Masliah, Mario Perello, Roland Riek, Juan Atilio Gerez
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-18 (2024)
Abstract Parkinson’s disease is characterized by a progressive accumulation of alpha-Synuclein (αSyn) neuronal inclusions called Lewy bodies in the nervous system. Lewy bodies can arise from the cell-to-cell propagation of αSyn, which can occur v
Externí odkaz:
https://doaj.org/article/b475e19f60dc407d997399ffc8c7268c
Autor:
Benjamin B. Tournier, Farha Bouteldja, Quentin Amossé, Alekos Nicolaides, Marcelo Duarte Azevedo, Liliane Tenenbaum, Valentina Garibotto, Kelly Ceyzériat, Philippe Millet
Publikováno v:
ACS Omega, Vol 8, Iss 34, Pp 31225-31236 (2023)
Externí odkaz:
https://doaj.org/article/0b87a0d2a0e3445b8b4f0bd5ed767136
Autor:
Marcelo Duarte Azevedo, Naika Prince, Marie Humbert-Claude, Virginia Mesa-Infante, Cheryl Jeanneret, Valentine Golzne, Kevin De Matos, Benjamin Boury Jamot, Fulvio Magara, Tomas Gonzalez-Hernandez, Liliane Tenenbaum
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 31, Iss , Pp 101106- (2023)
Despite its established neuroprotective effect on dopaminergic neurons and encouraging phase I results, intraputaminal GDNF administration failed to demonstrate significant clinical benefits in Parkinson’s disease patients. Different human GDNF dos
Externí odkaz:
https://doaj.org/article/27de7faeb4064f578e9d61fcd69d1cdc
Autor:
Christelle Lasbleiz, Nadine Mestre-Francés, Gina Devau, Maria-Rosario Luquin, Liliane Tenenbaum, Eric J. Kremer, Jean-Michel Verdier
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Parkinson’s disease (PD) is a progressive CNS disorder that is primarily associated with impaired movement. PD develops over decades and is linked to the gradual loss of dopamine delivery to the striatum, via the loss of dopaminergic (DA) neurons i
Externí odkaz:
https://doaj.org/article/690da4a35a0d40b184ac3bc5f5ed66ea
Autor:
Pedro Barroso-Chinea, Ignacio Cruz-Muros, Domingo Afonso-Oramas, Javier Castro-Hernández, Josmar Salas-Hernández, Abdelwahed Chtarto, Diego Luis-Ravelo, Marie Humbert-Claude, Liliane Tenenbaum, Tomás González-Hernández
Publikováno v:
Neurobiology of Disease, Vol 88, Iss , Pp 44-54 (2016)
The dopamine (DA) transporter (DAT) is a plasma membrane glycoprotein expressed in dopaminergic (DA-) cells that takes back DA into presynaptic neurons after its release. DAT dysfunction has been involved in different neuro-psychiatric disorders incl
Externí odkaz:
https://doaj.org/article/e4b338257bdd4dbba1852aa469aa5533
Publikováno v:
Journal of Clinical Medicine, Vol 9, Iss 2, p 456 (2020)
In a healthy adult brain, glial cell line-derived neurotrophic factor (GDNF) is exclusively expressed by neurons, and, in some instances, it has also been shown to derive from a single neuronal subpopulation. Secreted GDNF acts in a paracrine fashion
Externí odkaz:
https://doaj.org/article/8533c642f0474f52bbe1cc74b9ab9189
Publikováno v:
Neurobiology of Disease, Vol 79, Iss , Pp 14-27 (2015)
Among cerebral creatine deficiency syndromes, guanidinoacetate methyltransferase (GAMT) deficiency can present the most severe symptoms, and is characterized by neurocognitive dysfunction due to creatine deficiency and accumulation of guanidinoacetat
Externí odkaz:
https://doaj.org/article/def5153728214b91830e0eb900f1bb74
Autor:
Abdelwahed Chtarto, Marie Humbert-Claude, Olivier Bockstael, Atze T Das, Sébastien Boutry, Ludivine S Breger, Bep Klaver, Catherine Melas, Pedro Barroso-Chinea, Tomas Gonzalez-Hernandez, Robert N Muller, Olivier DeWitte, Marc Levivier, Cecilia Lundberg, Ben Berkhout, Liliane Tenenbaum
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 3, Iss C (2016)
Preclinical and clinical data stress the importance of pharmacologically-controlling glial cell line-derived neurotrophic factor (GDNF) intracerebral administration to treat PD. The main challenge is finding a combination of a genetic switch and a dr
Externí odkaz:
https://doaj.org/article/777931018d894258974b7053b2660708
Autor:
Kadiombo Bantubungi, Carine Jacquard, Anita Greco, Annita Pintor, Abdelwahed Chtarto, Khalid Tai, Marie-Christine Galas, Liliane Tenenbaum, Nicole Déglon, Patrizia Popoli, Luisa Minghetti, Emmanuel Brouillet, Jacques Brotchi, Marc Levivier, Serge N. Schiffmann, David Blum
Publikováno v:
Neurobiology of Disease, Vol 18, Iss 1, Pp 206-217 (2005)
Minocycline has been shown to be neuroprotective in various models of neurodegenerative diseases. However, its potential in Huntington's disease (HD) models characterized by calpain-dependent degeneration and inflammation has not been investigated. H
Externí odkaz:
https://doaj.org/article/9d530a55c8ed4f0e9423d7b415f633f9
Publikováno v:
Neurobiology of Disease, Vol 17, Iss 3, Pp 359-366 (2004)
Minocycline, an antibiotic of the tetracycline family, has been shown to display neurorestorative or neuroprotective properties in various models of neurodegenerative diseases. In particular, it has been shown to delay motor alterations, inflammation
Externí odkaz:
https://doaj.org/article/392bca96ccba4533a9175ef7d66358d3