Tamizaje fitoquímico del extracto acuoso del jugo de Agave fourcroydes L.

Autor: Caridad Terry Espinosa, Walfrido Terrero Matos, Liliana Vicet Muro

Publikováno v: Agroecosistemas, Vol 7, Iss 3, Pp 112-116 (2020)

Esta investigación comprendió el estudio de jugo de Agave fourcroyde L, se realizó un trabajo que tuvo como objetivo determinar metabolitos secundarios que pudieran tener potencialidades insecticida contra las larvas de lepidópteros. Se realizó

Externí odkaz: https://doaj.org/article/fbff890847e04d249cc603fcd8f8cb52

Optimization and pharmacological validation of a leukocyte migration assay in zebrafish larvae for the rapid in vivo bioactivity analysis of anti-inflammatory secondary metabolites.

Autor: María Lorena Cordero-Maldonado, Dany Siverio-Mota, Liliana Vicet-Muro, Isabel María Wilches-Arizábala, Camila V Esguerra, Peter A M de Witte, Alexander D Crawford

Publikováno v: PLoS ONE, Vol 8, Iss 10, p e75404 (2013)

Over the past decade, zebrafish (Danio rerio) have emerged as an attractive model for in vivo drug discovery. In this study, we explore the suitability of zebrafish larvae to rapidly evaluate the anti-inflammatory activity of natural products (NPs) a

Externí odkaz: https://doaj.org/article/26aee21c95e4484e8ab1dc7f4c6a5ba5

In Silico Repurposing, Design, Synthesis and Biological Evaluation of Bisacodyl Analogues

Autor: Clotilde Ferroud, Yovani Marrero Ponce, Vicente J. Arán, Liliana Vicet Muro, Peter de Witte, Alexander D. Crawford, Vanessa Lerari, Marta Marín, Yankier Rivero Guerra, Maité Sylla-Iyarreta Veitía, Françoise Dumas, Rosa M. Giner, Dany Siverio Mota

Publikováno v: Proceedings of MOL2NET 2017, International Conference on Multidisciplinary Sciences, 3rd edition.

In a recent article was described in silico repositioning, design, synthesis, biological evaluation and structure-activity relationship (SAR) of an original class of anti-inflammatory agents based on a polyaromatic pharmacophore structurally related

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c3e498e9b2e816402a76142ea3ee4033
https://doi.org/10.3390/mol2net-03-05121

Fishing anti-inflammatories from known drugs: In silico repurposing, design, synthesis and biological evaluation of bisacodyl analogues

Autor: Yovani Marrero Ponce, Françoise Dumas, Rosa M. Giner, Peter de Witte, Vicente J. Arán, Clotilde Ferroud, Yankier Rivero Guerra, Maité Sylla-Iyarreta Veitía, Liliana Vicet Muro, Vanessa Lerari, Marta Marín, Dany Siverio Mota, Alexander D. Crawford

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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Current Topics in Medicinal Chemistry
Current Topics in Medicinal Chemistry, Bentham Science Publishers, 2017, 17 (25), ⟨10.2174/1568026617666170817161953⟩

Herein is described in silico repositioning, design, synthesis, biological evaluation and structure-activity relationship (SAR) of an original class of anti-inflammatory agents based on a polyaromatic pharmacophore structurally related to bisacodyl (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dd99c2959c6ddb45fd90f0913b27e66
http://hdl.handle.net/10261/169922

Phytochemical screening and evaluation of the central nervous system activity of the ethanolic extract of Eugenia clarensis Britton & P.Wilson

Autor: Nghia TM. Nguyen, Liliana Vicet-Muro, Dany Siverio-Mota, Maria E. Jorge-Rodriguez, Dulce M. González-Mosquera, Idelfonso Castañeda-Noa

Publikováno v: Journal of Pharmacy & Pharmacognosy Research, Vol 4, Iss 1, Pp 39-48 (2016)

Context: Eugenia clarensis Britton & P. Wilson is an endangered plant endemic of central region of Cuba. Aims: To perform phytochemical profile of ethanolic leaf extract of E. clarensis and evaluate its central nervous system (CNS) activity. Me

Externí odkaz: https://doaj.org/article/b96a2d2378b847048e745946f7c80b68