Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Liliana Sokol"'
Autor:
Liliana Sokol, Anne Cuypers, Anh-Co K. Truong, Ann Bouché, Katleen Brepoels, Joris Souffreau, Katerina Rohlenova, Stefan Vinckier, Luc Schoonjans, Guy Eelen, Mieke Dewerchin, Laura P.M.H. de Rooij, Peter Carmeliet
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract Translation of academic results into clinical practice is a formidable unmet medical need. Single-cell RNA-sequencing (scRNA-seq) studies generate long descriptive ranks of markers with predicted biological function, but without functional v
Externí odkaz:
https://doaj.org/article/492570d9ce634a2ab0014bdb23770e7c
Autor:
Vincent Geldhof, Laura P. M. H. de Rooij, Liliana Sokol, Jacob Amersfoort, Maxim De Schepper, Katerina Rohlenova, Griet Hoste, Adriaan Vanderstichele, Anne-Marie Delsupehe, Edoardo Isnaldi, Naima Dai, Federico Taverna, Shawez Khan, Anh-Co K. Truong, Laure-Anne Teuwen, François Richard, Lucas Treps, Ann Smeets, Ines Nevelsteen, Birgit Weynand, Stefan Vinckier, Luc Schoonjans, Joanna Kalucka, Christine Desmedt, Patrick Neven, Massimiliano Mazzone, Giuseppe Floris, Kevin Punie, Mieke Dewerchin, Guy Eelen, Hans Wildiers, Xuri Li, Yonglun Luo, Peter Carmeliet
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Tumor blood vessels contribute to cancer growth, invasion and metastasis. Here, by using single cell transcriptomics, the authors report an inventory of endothelial cell heterogeneity in patients with breast cancer, including a subtype that expresses
Externí odkaz:
https://doaj.org/article/f607566042124ddc85658b5b9cc9abac
Autor:
Nadine V. Conchinha, Liliana Sokol, Laure-Anne Teuwen, Koen Veys, Sébastien J. Dumas, Elda Meta, Melissa García-Caballero, Vincent Geldhof, Rongyuan Chen, Lucas Treps, Mila Borri, Pauline de Zeeuw, Kim D. Falkenberg, Charlotte Dubois, Magdalena Parys, Laura P.M.H. de Rooij, Katerina Rohlenova, Jermaine Goveia, Luc Schoonjans, Mieke Dewerchin, Guy Eelen, Xuri Li, Joanna Kalucka, Peter Carmeliet
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100508- (2021)
Summary: Endothelial cells (ECs) harbor distinct phenotypical and functional characteristics depending on their tissue localization and contribute to brain, eye, lung, and muscle diseases such as dementia, macular degeneration, pulmonary hypertension
Externí odkaz:
https://doaj.org/article/b2b20f8ce4a04a3ca684810cddf10920
Autor:
Sébastien J. Dumas, Elda Meta, Nadine V. Conchinha, Liliana Sokol, Rongyuan Chen, Mila Borri, Laure-Anne Teuwen, Koen Veys, Melissa García-Caballero, Vincent Geldhof, Lucas Treps, Pauline de Zeeuw, Kim D. Falkenberg, Charlotte Dubois, Magdalena Parys, Laura P.M.H. de Rooij, Katerina Rohlenova, Jermaine Goveia, Luc Schoonjans, Mieke Dewerchin, Guy Eelen, Xuri Li, Joanna Kalucka, Peter Carmeliet
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100523- (2021)
Summary: Endothelial cells (ECs) exhibit phenotypic and functional tissue specificities, critical for studies in the vascular field and beyond. Thus, tissue-specific methods for isolation of highly purified ECs are necessary. Kidney, spleen, and test
Externí odkaz:
https://doaj.org/article/529c5dbb57f9412cbdc0d63bd57e2948
Autor:
Liliana Sokol, Vincent Geldhof, Melissa García-Caballero, Nadine V. Conchinha, Sébastien J. Dumas, Elda Meta, Laure-Anne Teuwen, Koen Veys, Rongyuan Chen, Lucas Treps, Mila Borri, Pauline de Zeeuw, Kim D. Falkenberg, Charlotte Dubois, Magdalena Parys, Laura P.M.H. de Rooij, Jermaine Goveia, Katerina Rohlenova, Luc Schoonjans, Mieke Dewerchin, Guy Eelen, Xuri Li, Joanna Kalucka, Peter Carmeliet
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100489- (2021)
Summary: Endothelial cells (ECs) from the small intestine, colon, liver, and heart have distinct phenotypes and functional adaptations that are dependent on their physiological environment. Gut ECs adapt to low oxygen, heart ECs to contractile forces
Externí odkaz:
https://doaj.org/article/b2d1c9d6471848f7a2760df466f9d229
Publikováno v:
International Journal of Molecular Sciences
The dynamic crosstalk between the different components of the tumor microenvironment is critical to determine cancer progression, metastatic dissemination, tumor immunity, and therapeutic responses. Angiogenesis is critical for tumor growth, and abno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc7e268c4871c4c27278d6d3d2ba13e3
Autor:
Melissa García-Caballero, Magdalena Parys, Lucas Treps, Luc Schoonjans, Rongyuan Chen, Mila Borri, Guy Eelen, Vincent Geldhof, Peter Carmeliet, Mieke Dewerchin, Joanna Kalucka, Charlotte Dubois, Pauline de Zeeuw, Jermaine Goveia, Koen Veys, Laure-Anne Teuwen, Liliana Sokol, Nadine V. Conchinha, Sébastien J. Dumas, Elda Meta, Kim D. Falkenberg, Katerina Rohlenova, Xuri Li, Laura P.M.H. de Rooij
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100508-(2021)
Conchinha, N V, Sokol, L, Teuwen, L A, Veys, K, Dumas, S J, Meta, E, García-Caballero, M, Geldhof, V, Chen, R, Treps, L, Borri, M, de Zeeuw, P, Falkenberg, K D, Dubois, C, Parys, M, de Rooij, L P M H, Rohlenova, K, Goveia, J, Schoonjans, L, Dewerchin, M, Eelen, G, Li, X, Kalucka, J & Carmeliet, P 2021, ' Protocols for endothelial cell isolation from mouse tissues : brain, choroid, lung, and muscle ', STAR Protocols, vol. 2, no. 3, 100508 . https://doi.org/10.1016/j.xpro.2021.100508
STAR Protocols
Conchinha, N V, Sokol, L, Teuwen, L A, Veys, K, Dumas, S J, Meta, E, García-Caballero, M, Geldhof, V, Chen, R, Treps, L, Borri, M, de Zeeuw, P, Falkenberg, K D, Dubois, C, Parys, M, de Rooij, L P M H, Rohlenova, K, Goveia, J, Schoonjans, L, Dewerchin, M, Eelen, G, Li, X, Kalucka, J & Carmeliet, P 2021, ' Protocols for endothelial cell isolation from mouse tissues : brain, choroid, lung, and muscle ', STAR Protocols, vol. 2, no. 3, 100508 . https://doi.org/10.1016/j.xpro.2021.100508
STAR Protocols
Summary Endothelial cells (ECs) harbor distinct phenotypical and functional characteristics depending on their tissue localization and contribute to brain, eye, lung, and muscle diseases such as dementia, macular degeneration, pulmonary hypertension,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f2470f63ecc450689227e57d1db0de0
http://www.sciencedirect.com/science/article/pii/S266616672100215X
http://www.sciencedirect.com/science/article/pii/S266616672100215X
Autor:
Mila Borri, Sébastien J. Dumas, Elda Meta, Melissa García-Caballero, Guy Eelen, Joanna Kalucka, Peter Carmeliet, Kim D. Falkenberg, Mieke Dewerchin, Katerina Rohlenova, Luc Schoonjans, Xuri Li, Liliana Sokol, Laura P.M.H. de Rooij, Rongyuan Chen, Koen Veys, Nadine V. Conchinha, Laure-Anne Teuwen, Magdalena Parys, Lucas Treps, Vincent Geldhof, Jermaine Goveia, Charlotte Dubois, Pauline de Zeeuw
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100523-(2021)
STAR Protocols
Dumas, S J, Meta, E, Conchinha, N V, Sokol, L, Chen, R, Borri, M, Teuwen, L A, Veys, K, García-Caballero, M, Geldhof, V, Treps, L, de Zeeuw, P, Falkenberg, K D, Dubois, C, Parys, M, de Rooij, L P M H, Rohlenova, K, Goveia, J, Schoonjans, L, Dewerchin, M, Eelen, G, Li, X, Kalucka, J & Carmeliet, P 2021, ' Protocols for endothelial cell isolation from mouse tissues : kidney, spleen, and testis ', STAR Protocols, vol. 2, no. 3, 100523 . https://doi.org/10.1016/j.xpro.2021.100523
STAR Protocols
Dumas, S J, Meta, E, Conchinha, N V, Sokol, L, Chen, R, Borri, M, Teuwen, L A, Veys, K, García-Caballero, M, Geldhof, V, Treps, L, de Zeeuw, P, Falkenberg, K D, Dubois, C, Parys, M, de Rooij, L P M H, Rohlenova, K, Goveia, J, Schoonjans, L, Dewerchin, M, Eelen, G, Li, X, Kalucka, J & Carmeliet, P 2021, ' Protocols for endothelial cell isolation from mouse tissues : kidney, spleen, and testis ', STAR Protocols, vol. 2, no. 3, 100523 . https://doi.org/10.1016/j.xpro.2021.100523
Summary Endothelial cells (ECs) exhibit phenotypic and functional tissue specificities, critical for studies in the vascular field and beyond. Thus, tissue-specific methods for isolation of highly purified ECs are necessary. Kidney, spleen, and testi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9c701bcdb11d5df8841ea29851c7b9b
http://www.sciencedirect.com/science/article/pii/S2666166721002306
http://www.sciencedirect.com/science/article/pii/S2666166721002306
Autor:
Vincent Geldhof, Laura P. M. H. de Rooij, Liliana Sokol, Jacob Amersfoort, Maxim De Schepper, Katerina Rohlenova, Griet Hoste, Adriaan Vanderstichele, Anne-Marie Delsupehe, Edoardo Isnaldi, Naima Dai, Federico Taverna, Shawez Khan, Anh-Co K. Truong, Laure-Anne Teuwen, François Richard, Lucas Treps, Ann Smeets, Ines Nevelsteen, Birgit Weynand, Stefan Vinckier, Luc Schoonjans, Joanna Kalucka, Christine Desmedt, Patrick Neven, Massimiliano Mazzone, Giuseppe Floris, Kevin Punie, Mieke Dewerchin, Guy Eelen, Hans Wildiers, Xuri Li, Yonglun Luo, Peter Carmeliet
Publikováno v:
Geldhof, V, de Rooij, L P M H, Sokol, L, Amersfoort, J, De Schepper, M, Rohlenova, K, Hoste, G, Vanderstichele, A, Delsupehe, A-M, Isnaldi, E, Dai, N, Taverna, F, Khan, S, Truong, A-C K, Teuwen, L-A, Richard, F, Treps, L, Smeets, A, Nevelsteen, I, Weynand, B, Vinckier, S, Schoonjans, L, Kalucka, J, Desmedt, C, Neven, P, Mazzone, M, Floris, G, Punie, K, Dewerchin, M, Eelen, G, Wildiers, H, Li, X, Luo, Y & Carmeliet, P 2022, ' Single cell atlas identifies lipid-processing and immunomodulatory endothelial cells in healthy and malignant breast ', Nature Communications, vol. 13, no. 1, pp. 5511 . https://doi.org/10.1038/s41467-022-33052-y
Nature communications
Geldhof, V, de Rooij, L P M H, Sokol, L, Amersfoort, J, De Schepper, M, Rohlenova, K, Hoste, G, Vanderstichele, A, Delsupehe, A M, Isnaldi, E, Dai, N, Taverna, F, Khan, S, Truong, A C K, Teuwen, L A, Richard, F, Treps, L, Smeets, A, Nevelsteen, I, Weynand, B, Vinckier, S, Schoonjans, L, Kalucka, J, Desmedt, C, Neven, P, Mazzone, M, Floris, G, Punie, K, Dewerchin, M, Eelen, G, Wildiers, H, Li, X, Luo, Y & Carmeliet, P 2022, ' Single cell atlas identifies lipid-processing and immunomodulatory endothelial cells in healthy and malignant breast ', Nature Communications, vol. 13, 5511 . https://doi.org/10.1038/s41467-022-33052-y
Nature communications
Geldhof, V, de Rooij, L P M H, Sokol, L, Amersfoort, J, De Schepper, M, Rohlenova, K, Hoste, G, Vanderstichele, A, Delsupehe, A M, Isnaldi, E, Dai, N, Taverna, F, Khan, S, Truong, A C K, Teuwen, L A, Richard, F, Treps, L, Smeets, A, Nevelsteen, I, Weynand, B, Vinckier, S, Schoonjans, L, Kalucka, J, Desmedt, C, Neven, P, Mazzone, M, Floris, G, Punie, K, Dewerchin, M, Eelen, G, Wildiers, H, Li, X, Luo, Y & Carmeliet, P 2022, ' Single cell atlas identifies lipid-processing and immunomodulatory endothelial cells in healthy and malignant breast ', Nature Communications, vol. 13, 5511 . https://doi.org/10.1038/s41467-022-33052-y
Since a detailed inventory of endothelial cell (EC) heterogeneity in breast cancer (BC) is lacking, here we perform single cell RNA-sequencing of 26,515 cells (including 8433 ECs) from 9 BC patients and compare them to published EC taxonomies from lu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d770facb3d58d1eaa7504f050d74bd0
https://pubmed.ncbi.nlm.nih.gov/36127427
https://pubmed.ncbi.nlm.nih.gov/36127427
Autor:
Jermaine Goveia, Lin Lin, Geert Carmeliet, Dena Panovska, Andreas Pircher, Lena-Christin Conradi, Yizhi Liu, Lars Bolund, Stefan Vinckier, Liliana Sokol, Kim D. Falkenberg, Katerina Rohlenova, Guy Eelen, Tine Van Bergen, Huanming Yang, Rene J. Mclaughlin, Mieke Dewerchin, Abhishek Subramanian, Bernard Thienpont, Nadine Ectors, Tobias K. Karakach, Yonglun Luo, Lucas Treps, Jian Wang, Frank J. T. Staal, Joanna Kalucka, Shawez Khan, Xuri Li, Peter Carmeliet, Yingfeng Zheng, Luc Schoonjans, Laura P.M.H. de Rooij, Patrik De Haes, Melissa García-Caballero, Frederik De Smet, Laure-Anne Teuwen, Federico Taverna, Vincent Geldhof, Steve Stegen
Publikováno v:
Rohlenova, K, Goveia, J, García-Caballero, M, Subramanian, A, Kalucka, J, Treps, L, Falkenberg, K D, de Rooij, L P M H, Zheng, Y, Lin, L, Sokol, L, Teuwen, L-A, Geldhof, V, Taverna, F, Pircher, A, Conradi, L-C, Khan, S, Stegen, S, Panovska, D, De Smet, F, Staal, F J T, Mclaughlin, R J, Vinckier, S, Van Bergen, T, Ectors, N, De Haes, P, Wang, J, Bolund, L, Schoonjans, L, Karakach, T K, Yang, H, Carmeliet, G, Liu, Y, Thienpont, B, Dewerchin, M, Eelen, G, Li, X, Luo, Y & Carmeliet, P 2020, ' Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis ', Cell Metabolism, vol. 31, no. 4, pp. 862-877.e14 . https://doi.org/10.1016/j.cmet.2020.03.009
Cell Metabolism, 31(4), 862-877.e14. CELL PRESS
Cell metabolism
Cell Metabolism
Cell Metabolism, 31(4), 862-877.e14. CELL PRESS
Cell metabolism
Cell Metabolism
Endothelial cell (EC) metabolism is an emerging target for anti-angiogenic therapy in tumor angiogenesis and choroidal neovascularization (CNV), but little is known about individual EC metabolic transcriptomes. By single-cell RNA sequencing 28,337 mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58b2f5df47885e409e283717683a15d4
https://doi.org/10.1016/j.cmet.2020.03.009
https://doi.org/10.1016/j.cmet.2020.03.009