Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Liliana R, Stefan"'
Publikováno v:
European Journal of Pharmaceutical Sciences. 17:253-263
Purpose: To develop a computational method to rapidly evaluate human intestinal absorption, one of the drug properties included in the term ADME (Absorption, Distribution, Metabolism, Excretion). Poor ADME properties are the most important reason for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85672e4fb25216e8b676710f3277bd47
https://doi.org/10.1016/s0928-0987(02)00219-1
https://doi.org/10.1016/s0928-0987(02)00219-1
Publikováno v:
Perspectives in Drug Discovery and Design. 19:133-155
A drug protein binding model was constructed on the basis of protein-affinity data for154 drugs. The Multiple Computer-Automated Structure Evaluation program (M-CASE) was used for the construction of the model, which separates the total data set into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82108a431172a07ab84176be3cf7bc75
https://doi.org/10.1023/a:1008723723679
https://doi.org/10.1023/a:1008723723679
Autor:
Aaron G. Levitan, Liliana R. Stefan, Stephen R. Holbrook, Rui Zhang, Donna K. Hendrix, Steven E. Brenner
Publikováno v:
Stefan, Liliana R.; Zhang, Rui; Levitan, Aaron G.; Hendrix, Donna F.; Brenner, Steven E.; & Holbrook, Stephen R.(2005). MeRNA: a Database of Metal Ion Binding Sites in RNA Structures. Lawrence Berkeley National Laboratory. Lawrence Berkeley National Laboratory: Lawrence Berkeley National Laboratory. Retrieved from: http://www.escholarship.org/uc/item/39b6350t
Nucleic Acids Research
Nucleic Acids Research
Metal ions are essential for the folding of RNA into stable tertiary structures and for the catalytic activity of some RNA enzymes. To aid in the study of the roles of metal ions in RNA structural biology, we have created MeRNA (Metals in RNA), a com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f98894d45eac357c4f5acfa91e1218e7
http://www.escholarship.org/uc/item/39b6350t
http://www.escholarship.org/uc/item/39b6350t
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 17(4-5)
To develop a computational method to rapidly evaluate human intestinal absorption, one of the drug properties included in the term ADME (Absorption, Distribution, Metabolism, Excretion). Poor ADME properties are the most important reason for drug fai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::63768602f07bbe7526f5345f431d0e3d
https://pubmed.ncbi.nlm.nih.gov/12453615
https://pubmed.ncbi.nlm.nih.gov/12453615