Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Liliana Mendieta"'
Autor:
Roberto A. Galeana-Ascencio, Liliana Mendieta, Daniel I. Limon, Dino Gnecco, Joel L. Terán, María L. Orea, Alan Carrasco-Carballo
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 8164 (2023)
The β-secretase-1 enzyme (BACE-1) performs a key role in the production of beta-Amyloid protein (Aβ), which is associated with the development of Alzheimer’s disease (AD). The inhibition of BACE-1 has been an important pharmacological strategy in
Externí odkaz:
https://doaj.org/article/7587cf5c37f245439bfa837ee2909b0b
Autor:
Irving Parra, Isabel Martínez, Lizbeth Vásquez-Celaya, Jose L. Gongora-Alfaro, Yousef Tizabi, Liliana Mendieta
Publikováno v:
Neurotoxicity Research. 41:187-200
Autor:
Carrasco-Carballo, Roberto A. Galeana-Ascencio, Liliana Mendieta, Daniel I. Limon, Dino Gnecco, Joel L. Terán, María L. Orea, Alan
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 9; Pages: 8164
The β-secretase-1 enzyme (BACE-1) performs a key role in the production of beta-Amyloid protein (Aβ), which is associated with the development of Alzheimer’s disease (AD). The inhibition of BACE-1 has been an important pharmacological strategy in
Autor:
José Aguilera, Liliana Mendieta, Felipe Patricio, Sergio Montes, Aleidy Patricio-Martínez, Ilhuicamina Daniel Limón, Francisca Pérez-Severiano, Daniel Juárez-Torres
Publikováno v:
Neuroscience Research. 174:36-45
The recombinant carboxyl-terminal domain of the heavy chain of tetanus toxin (Hc-TeTx) exerts neuroprotective and neurorestorative effects on the dopaminergic system of animal models of Parkinson's disease (PD). The present study aimed to determine t
Autor:
Pedro Efraín Hernández-Arrambide, Alan Carrasco-Carballo, Irving Parra, Delfino Chamorro-Arenas, Isabel Martínez, Félix Luna, Fernando Sartillo-Piscil, Yousef Tizabi, Liliana Mendieta
Publikováno v:
The international journal of neuropsychopharmacology.
Background Paroxetine (PX) is a widely used antidepressant with side effects such as weakness, dizziness, and trouble sleeping. In search of novel compounds with better efficacy and fewer side effects, we synthesized 3HPX, a hydroxylated analog of PX
Autor:
Isabel Martínez, Irving Parra, Liliana Mendieta, Félix Luna, Victorino Alatriste, Daniel Limon
Publikováno v:
Archivos de Neurociencias. 25:61-76
Tetanus toxin is a polypeptide of 1315 aminoacids of 150 kDa, from which a non-toxic fraction of 50 kDa is extracted that has the ability to cross the blood brain barrier through mechanisms that full-length toxin, have developed to throughout its evo
Autor:
José Aguilera, Daniel Limon, Natalia Moreno-Galarza, Liliana Mendieta, Carles Gil, Mireia Herrando-Grabulosa, Victoria Palafox-Sánchez
Publikováno v:
Neurotoxicity Research. 34:47-61
Several studies have shown that intrastriatal application of 1-methyl-4-phenylpyridinium (MPP+) produces similar biochemical changes in rat to those seen in Parkinson's disease (PD), such as dopaminergic terminal degeneration and consequent appearanc
Publikováno v:
Neuropeptides. 67:9-19
Memory impairment by the Amyloid-β 25–35 (Aβ25–35) peptide in animal models has provided an understanding of the causes behind the similar deterioration that occurs in Alzheimer's disease. However, it is uncertain if a decrease of dendritic spi
Autor:
Liliana Mendieta, Isabel Rodríguez Martínez, Gabriel Ramirez-Garcia, Yousef Tizabi, Irving Parra
Publikováno v:
Neurotoxicity research. 37(1)
Parkinson’s disease (PD) is an idiopathic and progressive neurodegenerative disease characterized by the loss of ~ 80% of dopaminergic neurons in substantia nigra pars compacta (SNpc). Because activation of the innate cellular immune response, medi
Autor:
Héctor Alonso Romero-Sánchez, Maria Elena Castellanos-Páez, Julia Pérez-Ramos, Yoshajandith Aguirre-Vidal, Liliana Mendieta, Beatriz Godínez-Chaparro, Gabriela Garza-Mouriño, Marcela Ivonne Benítez-Díaz Mirón, Cristina Rodríguez-Ramos
Publikováno v:
European Journal of Pharmacology. 889:173537
Pain is a usual and troublesome non-motor symptom of Parkinson's disease, with a prevalence of 29–82%. Therefore, it's vital to find pharmacological treatments for managing PD-associated pain symptoms, to improve patients' quality of life. For this