Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Liliana Maria Elena Finocchiaro"'
Publikováno v:
Gene Therapy. 26:418-431
After 6 years of follow-up treating 364 canine melanoma patients, we present here results about the proof-of-concept, safety, and efficacy of a new surgery adjuvant combined gene therapy. The adjuvant treatment (AT) group was divided in three arms as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86a306aee760658f3ad478573d793354
https://doi.org/10.1038/s41434-019-0066-7
https://doi.org/10.1038/s41434-019-0066-7
Autor:
Gerardo Claudio Glikin, Marcela Solange Villaverde, Lucrecia Agnetti, Liliana Maria Elena Finocchiaro, E. Breininger, María Florencia Arbe
Publikováno v:
Translational Oncology, Vol 13, Iss 11, Pp 100842-(2020)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Translational Oncology
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Translational Oncology
Most cancer cells exacerbate the pentose phosphate pathway (PPP) to enhance biosynthetic precursors and antioxidant defenses. Metformin, which is used as a first-line oral drug for the treatment of type 2 diabetes, has been proposed to inhibit the ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c875fde0fce7e08aa7220eb58bd2eb5
https://www.sciencedirect.com/science/article/pii/S193652332030334X?via=ihub#!
https://www.sciencedirect.com/science/article/pii/S193652332030334X?via=ihub#!
Autor:
Liliana Maria Elena Finocchiaro, Chiara Fondello, Matías Nicolás Tellado, Marcela Solange Villaverde, Lucrecia Agnetti, María Florencia Arbe, Gabriel Martín Alvarez, Gerardo Claudio Glikin
Publikováno v:
Research in Veterinary Science. 114:461-468
Feline mammary carcinoma (FMC) is a highly aggressive pathology that has been proposed as an interesting model of breast cancer disease, especially for the hormone refractory subgroup. Recently, cancer cell metabolism has been described as a hallmark
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c2bffd075c51e3f1c3a849d0236cbf0
https://doi.org/10.1016/j.rvsc.2017.07.035
https://doi.org/10.1016/j.rvsc.2017.07.035
Autor:
Lucrecia Agnetti, Marcela Solange Villaverde, Gerardo Claudio Glikin, Chiara Fondello, Liliana Maria Elena Finocchiaro
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Oncoscience
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Oncoscience
We originated and characterized melanoma cell lines derived from tumors of two feline and two canine veterinary patients. These lines reestablished the morphology, physiology and cell heterogeneity of their respective parental tumors. We evaluated th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80eb9acd54972d558055fc30ad46f155
http://impactjournals.com/oncoscience/index.php?pii=387
http://impactjournals.com/oncoscience/index.php?pii=387
Autor:
Kristell Combe, Marcela Solange Villaverde, Liliana Maria Elena Finocchiaro, Gerardo Claudio Glikin, Ming X Wei, Adriana Duchene
Publikováno v:
International Immunopharmacology. 22:167-175
In an aggressive B16-F10 murine melanoma model, we evaluated the effectiveness and antitumor mechanisms triggered by a surgery adjuvant treatment that combined a local suicide gene therapy (SG) with a subcutaneous genetic vaccine (Vx) composed by B16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::771ed420727e9b824d97a81c7a2ec2e4
https://doi.org/10.1016/j.intimp.2014.06.021
https://doi.org/10.1016/j.intimp.2014.06.021
Expression and purification of recombinant feline interferon in the baculovirus-insect larvae system
Autor:
Alexandra Marisa Targovnik, Oscar Taboga, Liliana Maria Elena Finocchiaro, Mariana Bernadett Arregui, Mariela Noemi Fogar, Maria Victoria Miranda, Osvaldo Cascone, Gerardo C. Glikin, Marcela Solange Villaverde
Publikováno v:
Process Biochemistry. 49:917-926
Feline interferons (FeIFNs) are cytokines with antiviral, antitumor and immunomodulatory functions used as therapeutic agents in a variety of veterinary diseases. In this work, FeIFN-α7 and FeIFN-α7xArg containing eight residues of arginine were ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::079d94ef6facae119f7a1c5f09d0cb88
https://doi.org/10.1016/j.procbio.2014.03.013
https://doi.org/10.1016/j.procbio.2014.03.013
Publikováno v:
The Scientific World Journal, Vol 2014 (2014)
The Scientific World Journal
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
The Scientific World Journal
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Despite the important progress obtained in the treatment of some pets’ malignancies, new treatments need to be developed. Being critical in cancer control and progression, the immune system’s appropriate modulation may provide effective therapeut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::543fabcc1a019fd839547b44e28a88d3
https://doi.org/10.1155/2014/718520
https://doi.org/10.1155/2014/718520
Autor:
Liliana Maria Elena Finocchiaro, Maria Victoria Miranda, Marcela Solange Villaverde, Gerardo Claudio Glikin, Alexandra Marisa Targovnik
Progress in comparative oncology promises advances in clinical cancer treatments for both companion animals and humans. In this context, feline mammary carcinoma (FMC) cells have been proposed as a suitable model to study human breast cancer. Based o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d699f6e0f00d9695a8d726b96de15994
https://www.sciencedirect.com/science/article/pii/S1043466616301119
https://www.sciencedirect.com/science/article/pii/S1043466616301119
Publikováno v:
Anti-cancer agents in medicinal chemistry. 17(5)
We evaluated the cytotoxic effects of the combination of bortezomib (BTZ) and interferon-β (IFNβ) gene lipofection on cultured melanoma cells. Four canine mucosal (Ak, Br, Bk and Ol) and two human dermal (A375 and SB2) melanoma cell lines were assa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e8d8af52a885c889b3166c2b416683f
https://pubmed.ncbi.nlm.nih.gov/27677689
https://pubmed.ncbi.nlm.nih.gov/27677689
Autor:
María L. Gil-Cardeza, Gerardo Claudio Glikin, Marcela Solange Villaverde, Liliana Maria Elena Finocchiaro
Publikováno v:
Cancer Gene Therapy. 19:508-516
We evaluated the effect of hIFNβ gene transfer alone or in combination with different antineoplastic drugs commonly used in cancer treatment. Five human tumor-derived cell lines were cultured as monolayers and spheroids. Four cell lines (Ewing sarco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::559d62705ad6992f3f27c696224e63e4
https://doi.org/10.1038/cgt.2012.27
https://doi.org/10.1038/cgt.2012.27