Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Liliana Mancio-Silva"'
Autor:
Camilla Luiza-Batista, Sabine Thiberge, Malika Serra-Hassoun, Flore Nardella, Aurélie Claës, Vanessa C. Nicolete, Pierre-Henri Commère, Liliana Mancio-Silva, Marcelo U. Ferreira, Artur Scherf, Sylvie Garcia
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Plasmodium vivax is the most widespread human malaria parasite but due to its tropism for immature red blood cells in vitro culturing and studies are difficult. Here, LuizaBatista et al. generate a humanized mouse supporting human erythropoiesis and
Externí odkaz:
https://doaj.org/article/efe541ad29ea4364a4ae5568530e9226
Autor:
Flore Nardella, Irina Dobrescu, Haitham Hassan, Fabien Rodrigues, Sabine Thiberge, Liliana Mancio-Silva, Ambre Tafit, Corinne Jallet, Véronique Cadet-Daniel, Stéphane Goussin, Audrey Lorthiois, Yoann Menon, Nicolas Molinier, Dany Pechalrieu, Christophe Long, François Sautel, Mariette Matondo, Magalie Duchateau, Guillaume Médard, Benoit Witkowski, Artur Scherf, Ludovic Halby, Paola B. Arimondo
Publikováno v:
iScience, Vol 26, Iss 2, Pp 105940- (2023)
Summary: Malaria eradication requires the development of new drugs to combat drug-resistant parasites. We identified bisbenzylisoquinoline alkaloids isolated from Cocculus hirsutus that are active against Plasmodium falciparum blood stages. Synthesis
Externí odkaz:
https://doaj.org/article/f12af47207ad40a38e61010f2bc8e9c9
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 5, Iss 2, Pp 131-144 (2018)
Engineered liver systems come in a variety of platform models, from 2-dimensional cocultures of primary human hepatocytes and stem cell–derived progeny, to 3-dimensional organoids and humanized mice. Because of the species-specificity of many human
Externí odkaz:
https://doaj.org/article/7aad1d46622a4a739da3677dcc26d9bf
Autor:
Margarida T. Grilo Ruivo, Iset Medina Vera, Joana Sales-Dias, Patrícia Meireles, Nil Gural, Sangeeta N. Bhatia, Maria M. Mota, Liliana Mancio-Silva
Publikováno v:
Cell Reports, Vol 16, Iss 10, Pp 2539-2545 (2016)
Manipulation of the master regulator of energy homeostasis AMP-activated protein kinase (AMPK) activity is a strategy used by many intracellular pathogens for successful replication. Infection by most pathogens leads to an activation of host AMPK act
Externí odkaz:
https://doaj.org/article/96f97c3fa6cb409b84c49c9a66d0a99d
Autor:
Whitney A. Scoon, Liliana Mancio-Silva, Ellen L. Suder, Carlos Villacorta-Martin, Jonathan Lindstrom-Vautrin, John G. Bernbaum, Steve Mazur, Reed F. Johnson, Judith Olejnik, Elizabeth Y. Flores, Aditya Mithal, Feiya Wang, Adam J. Hume, Joseph E. Kaserman, Sandra March-Riera, Andrew A. Wilson, Sangeeta N. Bhatia, Elke Mühlberger, Gustavo Mostoslavsky
Publikováno v:
Stem Cell Reports. 17:2286-2302
Liver damage and an exacerbated inflammatory response are hallmarks of Ebola virus (EBOV) infection. Little is known about the intrinsic response to infection in human hepatocytes and their contribution to inflammation. Here, we present an induced pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ffeb13201a033f5fc7e06ff6b920967
https://doi.org/10.1016/j.stemcr.2022.08.003
https://doi.org/10.1016/j.stemcr.2022.08.003
Autor:
Liliana Mancio Silva, Eliana Real
Publikováno v:
Trends in Parasitology
Trends in Parasitology, 2022, 38 (9), pp.748-757. ⟨10.1016/j.pt.2022.05.009⟩
Trends in Parasitology, 2022, 38 (9), pp.748-757. ⟨10.1016/j.pt.2022.05.009⟩
International audience; Malaria-causing Plasmodium parasites undergo multiple phenotypic transitions as they cycle between diverse niches in the mammalian and mosquito hosts. Recent applications of single-cell technologies to Plasmodium have enabled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::661b7252506da5ac26834e92ad285ed7
https://doi.org/10.1016/j.pt.2022.05.009
https://doi.org/10.1016/j.pt.2022.05.009
Autor:
Flore Nardella, Irina Dobrescu, Haitham Hassan, Fabien Rodrigues, Sabine Thiberge, Liliana Mancio Silva, Ambre Tafit, Corinne Jallet, Véronique Cadet-Daniel, Stéphane Goussin, Audrey Lorthiois, Yoann Menon, Nicolas Molinier, Dany Pechalrieu, Christophe Long, François Sautel, Mariette Matondo, Magalie Duchateau, Guillaume Medard, Benoit Witkowski, Artur Scherf, Ludovic Halby, Paola B. Arimondo
Malaria eradication requires the development of new drugs to combat drug-resistant parasites. The search for new chemical scaffolds that target novel pathways of the human malaria parasite Plasmodium falciparum is of highest priority. We identified b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5660d998302935d987b9c8699ee1b0ff
https://doi.org/10.1101/2022.08.30.505923
https://doi.org/10.1101/2022.08.30.505923
Publikováno v:
Trends in Parasitology
Trends in Parasitology, 2021, 37 (10), pp.853-855. ⟨10.1016/j.pt.2021.07.007⟩
Trends in Parasitology, 2021, 37 (10), pp.853-855. ⟨10.1016/j.pt.2021.07.007⟩
International audience; Microbiota composition recently arose as a factor correlating with malaria infection. Mandal et al. showed, via cecal transplant and antibacterial treatment, that the mouse microbiota modulates parasitemia by affecting spleen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8baf62c30ba3a5040ae621344eb2b0f4
https://doi.org/10.1016/j.pt.2021.07.007
https://doi.org/10.1016/j.pt.2021.07.007
Publikováno v:
Current Opinion in Microbiology. 70:102207
A commonly observed survival strategy in protozoan parasites is the sequential expression of clonally variant-surface antigens to avoid elimination by the host's immune response. In malaria-causing P. falciparum, the immunovariant erythrocyte-membran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c944c95d0ce96053ab82eb20d59f1f4b
https://doi.org/10.1016/j.mib.2022.102207
https://doi.org/10.1016/j.mib.2022.102207
Autor:
Liliana Mancio-Silva, Nil Gural, Alex K. Shalek, Niketa Nerurkar, Sandra March, Jetsumon Sattabongkot, Stuart S. Levine, Travis K. Hughes, Marc H. Wadsworth, Vincent L. Butty, Sangeeta N. Bhatia, Charles A. Whittaker, Heather E. Fleming, Wanlapa Roobsoong
SUMMARYMalaria-causing P. vivax parasites can linger in the human liver for weeks to years, and then reactivate to cause recurrent blood-stage infection. While an important target for malaria eradication, little is known about the molecular features
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::662ac7caed4e1810d62985083fda84c2
https://doi.org/10.1101/2021.09.01.454555
https://doi.org/10.1101/2021.09.01.454555