Výsledky vyhledávání - "Liliana Cozzoli"

Novel, potent and selective 17β-hydroxysteroid dehydrogenase type 2 inhibitors as potential therapeutics for osteoporosis with dual human and mouse activities

Autor: Nina Hanke, Emanuele M. Gargano, Enrico Perspicace, Rolf W. Hartmann, Sandrine Marchais-Oberwinkler, Angelo Carotti, Liliana Cozzoli

Publikováno v: European journal of medicinal chemistry. 83

17β-Hydroxysteroid dehydrogenase type 2 (17β-HSD2) is responsible for the oxidation of the highly active estradiol (E2) and testosterone (T) into the less potent estrone (E1) and Δ4-androstene-3,17-dione (Δ4-AD), respectively. As 17β-HSD2 is pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58a74c144421a220184d9b0643de195e
https://pubmed.ncbi.nlm.nih.gov/24974351

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