Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Liliana Cantini"'
Autor:
Liliana Cantini, Christopher C Attaway, Betsy Butler, Lourdes M Andino, Melissa L Sokolosky, Andrew Jakymiw
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73348 (2013)
Despite a better understanding of the pathogenesis of oral cancer, its treatment outcome remains poor. Thus, there is a need for new therapeutic strategies to improve the prognosis of this disease. RNA interference (RNAi) appears to be a promising th
Externí odkaz:
https://doaj.org/article/da845dff242f4693b289d608976945a4
Autor:
Lourdes M. Andino, Laurence Eggart, Liliana Cantini, Christopher C. Attaway, Andrew Jakymiw, Haiwen Zhang, Angela Alexander-Bryant, Lu Dinh, Robert M. Sansevere, William Pugh
Publikováno v:
Oral Oncology. 72:123-131
Despite significant advances in cancer treatment, the prognosis for oral cancer remains poor in comparison to other cancer types, including breast, skin, and prostate. As a result, more effective therapeutic modalities are needed for the treatment of
Autor:
Eric Meggers, Bin Fang, Jobin K. John, Clemens Krepler, Vito W. Rebecca, Victoria Izumi, Nicholas Pagano, Jane L. Messina, John M. Koomen, Keiran S.M. Smalley, Kim H. T. Paraiso, Ethan V. Abel, Meenhard Herlyn, Liliana Cantini, Rahel Mathew
Publikováno v:
The Journal of investigative dermatology
This study addresses the role of glycogen synthase kinase (GSK)-3β signaling in the tumorigenic behavior of melanoma. Immunohistochemical staining revealed GSK3β to be focally expressed in the invasive portions of 12 and 33% of primary and metastat
Autor:
Keiran S.M. Smalley, Kim H. T. Paraiso, Liliana Cantini, MacLean Hall, Vernon K. Sondak, Keith T. Flaherty, Jane L. Messina, Inna V. Fedorenko, Ana Cecelia Munko
Publikováno v:
British Journal of Cancer
Background: Resistance to BRAF inhibitors is an emerging problem in the melanoma field. Strategies to prevent and overcome resistance are urgently required. Methods: The dynamics of cell signalling, BrdU incorporation and cell-cycle entry after BRAF
Publikováno v:
Expert Opinion on Drug Discovery. 4:445-456
The past 30 years have seen little improvement in the survival of patients with stage IV melanoma. Following the discovery of activating BRAF mutations in most melanomas, a wealth of preclinical experimentation has validated the BRAF/MAPK pathway as
Autor:
Jacob Rajfer, Suzanne Reisz-Porszasz, Monica G. Ferrini, Freddi I. Zuniga, Thomas R. Magee, Dolores Vernet, Liliana Cantini, Nestor F. Gonzalez-Cadavid, Jorge N. Artaza
Publikováno v:
The Journal of Gene Medicine. 8:1171-1181
Background Myostatin negatively regulates skeletal muscle growth. Myostatin knockout mice exhibit muscle hypertrophy and decreased interstitial fibrosis. We investigated whether a plasmid expressing a short hairpin interfering RNA (shRNA) against myo
Autor:
Betsy Butler, Christopher C. Attaway, Andrew Jakymiw, Liliana Cantini, Lourdes M. Andino, Melissa L. Sokolosky
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 9, p e73348 (2013)
PLoS ONE, Vol 8, Iss 9, p e73348 (2013)
Despite a better understanding of the pathogenesis of oral cancer, its treatment outcome remains poor. Thus, there is a need for new therapeutic strategies to improve the prognosis of this disease. RNA interference (RNAi) appears to be a promising th
Autor:
Christopher C. Attaway, Angela Alexander-Bryant, Liliana Cantini, Robert M. Sansevere, Lu Dinh, Laurence Eggart, William Pugh, Andrew Jakymiw, Haiwen Zhang
Publikováno v:
Cancer Research. 76:2057-2057
Two major hurdles for small interfering RNA (siRNA)-mediated therapies are cell/tissue-type targeted delivery and endosomal entrapment of siRNAs, resulting in inefficient gene silencing. As a result, the objective of this study was to examine the fea
Autor:
Robert Gelfand, Nestor F. Gonzalez-Cadavid, Dolores Vernet, Jacob Rajfer, Ansha Qian, Monica G. Ferrini, Thomas R. Magee, Liliana Cantini
Publikováno v:
The journal of sexual medicine. 5(7)
Introduction The primary histologic finding in many urologic disorders, including Peyronie's disease (PD), is fibrosis, mainly mediated by the transforming growth factor β1 (TGFβ1). Aim To determine whether another member of the TGFβ family, myost
Autor:
Dolores, Vernet, Gaby, Nolazco, Liliana, Cantini, Thomas R, Magee, Ansha, Qian, Jacob, Rajfer, Nestor F, Gonzalez-Cadavid
Publikováno v:
Biology of reproduction. 73(6)
Tissue ossification in Peyronie disease (commonly known as Peyronie's disease [PD]), a localized fibrotic lesion within the tunica albuginea (TA) of the penis, may result from osteogenic differentiation of fibroblasts, myofibroblasts, and/or adult st