Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Liliana Bernardino"'
Autor:
Catarina Rebelo, Tiago Reis, Joana Guedes, Cláudia Saraiva, Artur Filipe Rodrigues, Susana Simões, Liliana Bernardino, João Peça, Sónia L. C. Pinho, Lino Ferreira
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Abstract Spatial control of gene expression is critical to modulate cellular functions and deconstruct the function of individual genes in biological processes. Light-responsive gene-editing formulations have been recently developed; however, they ha
Externí odkaz:
https://doaj.org/article/c7b23c15dc4c4965aa7f743648a55671
Autor:
Marta Machado-Pereira, Cláudia Saraiva, Liliana Bernardino, Ana C. Cristóvão, Raquel Ferreira
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-17 (2022)
Abstract Background The brain vasculature plays a pivotal role in the inflammatory process by modulating the interaction between blood cells and the neurovascular unit. Argonaute-2 (Ago2) has been suggested as essential for endothelial survival but i
Externí odkaz:
https://doaj.org/article/7aaa0f381b604b4a99a42b7d092771eb
Autor:
Catarina Rebelo, Tiago Reis, Joana Guedes, Cláudia Saraiva, Artur Filipe Rodrigues, Susana Simões, Liliana Bernardino, João Peça, Sónia L. C. Pinho, Lino Ferreira
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/83068e9a94e742608c1b26158847f1d9
Autor:
Vanessa Brito, Mariana Marques, Marta Esteves, Catarina Serra-Almeida, Gilberto Alves, Paulo Almeida, Liliana Bernardino, Samuel Silvestre
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 812 (2023)
Steroids constitute an important class of pharmacologically active molecules, playing key roles in human physiology. Within this group, 16E-arylideneandrostane derivatives have been reported as potent anti-cancer agents for the treatment of leukemia,
Externí odkaz:
https://doaj.org/article/019e73192d8742048d2bea6255ec3ac9
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Retinoids are involved in a wide range of cellular functions; as such, delivery systems for retinoids are of significant clinical interest. Here the authors review the advances in preclinical and clinical testing regarding retinoid formulations in th
Externí odkaz:
https://doaj.org/article/1e0417eeae784ebbb9edeff05e12069a
Autor:
Catarina Serra-Almeida, Cláudia Saraiva, Marta Esteves, Raquel Ferreira, Tiago Santos, Ana Clara Cristóvão, Liliana Bernardino
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
C-terminal binding proteins (CtBPs) are transcriptional modulators that can regulate gene expression through the recruitment of a corepressor complex composed of chromatin-modifying enzymes and transcriptional factors. In the brain, CtBPs have been d
Externí odkaz:
https://doaj.org/article/5eb2ab7c9c684cd58a533131a36d7546
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Externí odkaz:
https://doaj.org/article/c520f24b54b34af4846cecd68b960dc0
Autor:
Sezin Aday, Janet Zoldan, Marie Besnier, Laura Carreto, Jaimy Saif, Rui Fernandes, Tiago Santos, Liliana Bernardino, Robert Langer, Costanza Emanueli, Lino Ferreira
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Soluble vascular endothelial growth factor (VEGF) enhances vascular engraftment of transplanted cells but the efficacy is low. Here, the authors show that VEGF-immobilized microparticles prolong survival of endothelial progenitors in vitro and in viv
Externí odkaz:
https://doaj.org/article/cc9c6eafaf1e4d7fa795b816dacd8e45
Autor:
Cláudia Saraiva, Daniela Talhada, Akhilesh Rai, Raquel Ferreira, Lino Ferreira, Liliana Bernardino, Karsten Ruscher
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0193609 (2018)
There is a high quest for novel therapeutic strategies to enhance recovery after stroke. MicroRNA-124 (miR-124) has been described as neuroprotective and anti-inflammatory molecule. Moreover, miR-124 is a well described enhancer of adult neurogenesis
Externí odkaz:
https://doaj.org/article/03a116568cb44982974ba8c559a95051
Publikováno v:
Mediators of Inflammation, Vol 2017 (2017)
Inflammatory mechanisms triggered by microglial cells are involved in the pathophysiology of several brain disorders, hindering repair. Herein, we propose the use of retinoic acid-loaded polymeric nanoparticles (RA-NP) as a means to modulate microgli
Externí odkaz:
https://doaj.org/article/227b3bb63cf042ed84517e1c4fb2ecbb