CCNE1 and survival of patients with tubo-ovarian high-grade serous carcinoma

Autor: Eun-Young, Kang, Ashley, Weir, Nicola S, Meagher, Kyo, Farrington, Gregg S, Nelson, Prafull, Ghatage, Cheng-Han, Lee, Marjorie J, Riggan, Adelyn, Bolithon, Gordana, Popovic, Betty, Leung, Katrina, Tang, Neil, Lambie, Joshua, Millstein, Jennifer, Alsop, Michael S, Anglesio, Beyhan, Ataseven, Ellen, Barlow, Matthias W, Beckmann, Jessica, Berger, Christiani, Bisinotto, Hans, Bösmüller, Jessica, Boros, Alison H, Brand, Angela, Brooks-Wilson, Sara Y, Brucker, Michael E, Carney, Yovanni, Casablanca, Alicia, Cazorla-Jiménez, Paul A, Cohen, Thomas P, Conrads, Linda S, Cook, Penny, Coulson, Madeleine, Courtney-Brooks, Daniel W, Cramer, Philip, Crowe, Julie M, Cunningham, Cezary, Cybulski, Kathleen M, Darcy, Mona A, El-Bahrawy, Esther, Elishaev, Ramona, Erber, Rhonda, Farrell, Sian, Fereday, Anna, Fischer, María J, García, Simon A, Gayther, Aleksandra, Gentry-Maharaj, C Blake, Gilks, Marcel, Grube, Paul R, Harnett, Shariska Petersen, Harrington, Philipp, Harter, Arndt, Hartmann, Jonathan L, Hecht, Sebastian, Heikaus, Alexander, Hein, Florian, Heitz, Joy, Hendley, Brenda Y, Hernandez, Susanna Hernando, Polo, Sabine, Heublein, Akira, Hirasawa, Estrid, Høgdall, Claus K, Høgdall, Hugo M, Horlings, David G, Huntsman, Tomasz, Huzarski, Andrea, Jewell, Mercedes, Jimenez-Linan, Michael E, Jones, Scott H, Kaufmann, Catherine J, Kennedy, Dineo, Khabele, Felix K F, Kommoss, Roy F P M, Kruitwagen, Diether, Lambrechts, Nhu D, Le, Marcin, Lener, Jenny, Lester, Yee, Leung, Anna, Linder, Liselore, Loverix, Jan, Lubiński, Rashna, Madan, G Larry, Maxwell, Francesmary, Modugno, Susan L, Neuhausen, Alexander, Olawaiye, Siel, Olbrecht, Sandra, Orsulic, José, Palacios, Celeste Leigh, Pearce, Malcolm C, Pike, Carmel M, Quinn, Ganendra Raj, Mohan, Cristina, Rodríguez-Antona, Matthias, Ruebner, Andy, Ryan, Stuart G, Salfinger, Naoko, Sasamoto, Joellen M, Schildkraut, Minouk J, Schoemaker, Mitul, Shah, Raghwa, Sharma, Yurii B, Shvetsov, Naveena, Singh, Gabe S, Sonke, Linda, Steele, Colin J R, Stewart, Karin, Sundfeldt, Anthony J, Swerdlow, Aline, Talhouk, Adeline, Tan, Sarah E, Taylor, Kathryn L, Terry, Aleksandra, Tołoczko, Nadia, Traficante, Koen K, Van de Vijver, Maaike A, van der Aa, Toon, Van Gorp, Els, Van Nieuwenhuysen, Lilian, van-Wagensveld, Ignace, Vergote, Robert A, Vierkant, Chen, Wang, Lynne R, Wilkens, Stacey J, Winham, Anna H, Wu, Javier, Benitez, Andrew, Berchuck, Francisco J, Candido Dos Reis, Anna, DeFazio, Peter A, Fasching, Ellen L, Goode, Marc T, Goodman, Jacek, Gronwald, Beth Y, Karlan, Stefan, Kommoss, Usha, Menon, Hans-Peter, Sinn, Annette, Staebler, James D, Brenton, David D, Bowtell, Paul D P, Pharoah, Susan J, Ramus, Martin, Köbel

Publikováno v: Cancer, 129(5), 697-713. Wiley
Cancer: interdisciplinary international journal of the American Cancer Society

BACKGROUND: Cyclin E1 (CCNE1) is a potential predictive marker and therapeutic target in tubo-ovarian high-grade serous carcinoma (HGSC). Smaller studies have revealed unfavorable associations for CCNE1 amplification and CCNE1 overexpression with sur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a712f975eda37f30b27613bbb4a613d2
https://cris.maastrichtuniversity.nl/en/publications/c478396c-2f30-41bf-8d8e-e8eb052ddffb

45/#732 Homologous recombination deficiency and cyclin E1 amplification are correlated with immune cell infiltration and survival in high-grade serous ovarian cancer

Autor: Lilian Van Wagensveld, Julliete Van Baal, Maite Timmermans, Duco Gaillard, Lauri Borghuis, Seth Coffelt, Effraim Rosenberg, Christianne Lok, Hans Nijman, Loes Kooreman, Annegien Broeks, Joyce Sanders, Marco De Bruijn, Rianne Van Der Wiel, Roy Kruitwagen, Maaike Van Der Aa, Gabe Sonke, Philip Schouten, Koen Van De Vijver, Hugo Horlings

Publikováno v: Featured Printed Posters (Poster Rounds with the Professors).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2090443cb138d6f7e7ea3783a99254c4
https://doi.org/10.1136/ijgc-2022-igcs.89

MCM3 is a novel proliferation marker associated with longer survival for patients with tubo-ovarian high-grade serous carcinoma

Autor: Thomas P. Conrads, Gordana C. Popovic, Lilian van-Wagensveld, Ignace Vergote, Ellen L. Barlow, Annalyn Da-Anoy, Stacey J. Winham, Nicola S. Meagher, Catherine J. Kennedy, Michael Jones, Sabine Heublein, Linda E. Kelemen, Neil Lambie, Paul D.P. Pharoah, Peter Sinn, Claus Høgdall, Sanela Bilic, Alexander Hein, Yovanni Casablanca, Aline Talhouk, Christiani Bisinotto, Chiu-Chen Tseng, Matthias Ruebner, Nhu D Le, Estrid Høgdall, Arndt Hartmann, Malcolm C. Pike, Philipp Harter, Nina Neudeck, Sarah Taylor, Juergen Andress, Anna Fischer, Kunle Odunsi, Naoko Sasamoto, Janine M. Joseph, Marina Pavanello, Derek S. Chiu, Eun Young Kang, Ellen L. Goode, Susan L. Neuhausen, Rhonda Farrell, Stefan Kommoss, Esther Elishaev, Jenny Lester, Yu Yu, Carmel Quinn, Betty Leung, Susan J. Ramus, Jesus Garcia-Donas, Colin J.R. Stewart, Penny Coulson, Joshua Millstein, Adelyn Bolithon, Maria Lycke, Chen Wang, Andreas du Bois, Francesmary Modugno, Alexander B. Olawaiye, Celeste Leigh Pearce, Jessica Boros, G. Larry Maxwell, Constantina Mateoiu, Francisco José Candido dos Reis, Diether Lambrechts, Liselore Loverix, Katrina Tang, Siel Olbrecht, John Lewis Etter, Yee Leung, Kirsten B. Moysich, Katherine LaVigne-Mager, Matthias W. Beckmann, Kathryn L. Terry, Felix K. F. Kommoss, Arantzazu Barquin-Garcia, Monica Yagüe-Fernandez, Sergio Ruiz-Llorente, Helen Steed, M Grube, Michael S Anglesio, Nikilyn Nevins, Sebastian M. Armasu, Mona El-Bahrawy, Beyhan Ataseven, Minouk J. Schoemaker, Annette Staebler, Peter A. Fasching, Gottfried E. Konecny, Terry K. Morgan, Simon A. Gayther, Anna deFazio, Robert A. Vierkant, Martin Köbel, Ramona Erber, Cheng-Han Lee, Paul R. Harnett, Greg Robertson, Linda S Cook, Philip J. Crowe, Daniel W. Cramer, Alison Brand, Yajue Huang, Anusha Hettiaratchi, Florian Heitz, Beth Y. Karlan, Anthony J. Swerdlow, Adeline Tan, Anna H. Wu, Akira Hirasawa, Kate Lawrenson, Karin Sundfeldt, Paul A. Cohen, Robert P. Edwards, Hugo M. Horlings

Publikováno v: Virchows Arch
Kang, E Y, Millstein, J, Popovic, G, Meagher, N S, Bolithon, A, Talhouk, A, Chiu, D S, Anglesio, M S, Leung, B, Tang, K, Lambie, N, Pavanello, M, Da-anoy, A, Lambrechts, D, Loverix, L, Olbrecht, S, Bisinotto, C, Garcia-Donas, J, Ruiz-Llorente, S, Yagüe-Fernandez, M, Edwards, R P, Elishaev, E, Olawaiye, A, Taylor, S, Ataseven, B, du Bois, A, Harter, P, Lester, J, Høgdall, C K, Armasu, S M, Huang, Y, Vierkant, R A, Wang, C, Winham, S J, Heublein, S, Kommoss, F K F, Cramer, D W, Sasamoto, N, van-Wagensveld, L, Lycke, M, Mateoiu, C, Joseph, J, Pike, M C, Odunsi, K, Tseng, C C, Pearce, C L, Bilic, S, Conrads, T P, Hartmann, A, Hein, A, Jones, M E, Leung, Y, Beckmann, M W, Ruebner, M, Schoemaker, M J, Terry, K L, El-Bahrawy, M A, Coulson, P, Etter, J L, LaVigne-Mager, K, Andress, J, Grube, M, Fischer, A, Neudeck, N, Robertson, G, Farrell, R, Barlow, E, Quinn, C, Hettiaratchi, A, Casablanca, Y, Erber, R, Stewart, C J R, Tan, A, Yu, Y, Boros, J, Brand, A H, Harnett, P R, Kennedy, C J, Nevins, N, Morgan, T, Fasching, P A, Vergote, I, Swerdlow, A J, Candido dos Reis, F J, Maxwell, G L, Neuhausen, S L, Barquin-Garcia, A, Modugno, F, Moysich, K B, Crowe, P J, Hirasawa, A, Heitz, F, Karlan, B Y, Goode, E L, Sinn, P, Horlings, H M, Høgdall, E, Sundfeldt, K, Kommoss, S, Staebler, A, Wu, A H, Cohen, P A, DeFazio, A, Lee, C H, Steed, H, Le, N D, Gayther, S A, Lawrenson, K, Pharoah, P D P, Konecny, G, Cook, L S, Ramus, S J, Kelemen, L E & Köbel, M 2022, ' MCM3 is a novel proliferation marker associated with longer survival for patients with tubo-ovarian high-grade serous carcinoma ', Virchows Archiv, vol. 480, pp. 855–871 . https://doi.org/10.1007/s00428-021-03232-0

Tubo-ovarian high-grade serous carcinomas (HGSC) are highly proliferative neoplasms that generally respond well to platinum/taxane chemotherapy. We recently identified minichromosome maintenance complex component 3 (MCM3), which is involved in the in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6e268638b52d1199839f66760e65433
https://pubmed.ncbi.nlm.nih.gov/34782936