Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Lilian Schimmel"'
Autor:
Janine JG Arts, Eike K Mahlandt, Max LB Grönloh, Lilian Schimmel, Ivar Noordstra, Emma Gordon, Abraham CI van Steen, Simon Tol, Barbara Walzog, Jos van Rijssel, Martijn A Nolte, Marten Postma, Satya Khuon, John M Heddleston, Eric Wait, Teng Leong Chew, Mark Winter, Eloi Montanez, Joachim Goedhart, Jaap D van Buul
Publikováno v:
eLife, Vol 10 (2021)
Upon inflammation, leukocytes rapidly transmigrate across the endothelium to enter the inflamed tissue. Evidence accumulates that leukocytes use preferred exit sites, alhough it is not yet clear how these hotspots in the endothelium are defined and h
Externí odkaz:
https://doaj.org/article/e8c403c2145749c68b603d43a3547e87
Autor:
Janine J. G. Arts, Eike K. Mahlandt, Lilian Schimmel, Max L. B. Grönloh, Sanne van der Niet, Bart J. A. M. Klein, Mar Fernandez-Borja, Daphne van Geemen, Stephan Huveneers, Jos van Rijssel, Joachim Goedhart, Jaap D. van Buul
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
An inflammatory response requires leukocytes to migrate from the circulation across the vascular lining into the tissue to clear the invading pathogen. Whereas a lot of attention is focused on how leukocytes make their way through the endothelial mon
Externí odkaz:
https://doaj.org/article/c305759e1af542afa349976b10539ac8
Autor:
Lilian Schimmel, Keng Yih Chew, Claudia J Stocks, Teodor E Yordanov, Patricia Essebier, Arutha Kulasinghe, James Monkman, Anna Flavia Ribeiro dosSantos Miggiolaro, Caroline Cooper, Lucia deNoronha, Kate Schroder, Anne Karine Lagendijk, Larisa I Labzin, Kirsty R Short, Emma J Gordon
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 10, Pp n/a-n/a (2021)
Abstract Objectives Thrombotic and microvascular complications are frequently seen in deceased COVID‐19 patients. However, whether this is caused by direct viral infection of the endothelium or inflammation‐induced endothelial activation remains
Externí odkaz:
https://doaj.org/article/fb13a66448274e4d8345aa44e4f79908
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Blood and lymphatic vessels are lined by endothelial cells which constantly interact with their luminal and abluminal extracellular environments. These interactions confer physical forces on the endothelium, such as shear stress, stretch and stiffnes
Externí odkaz:
https://doaj.org/article/9c8d39cfced84e7c927f8747133412b5
Autor:
Lilian Schimmel, Miesje van der Stoel, Carmela Rianna, Anne-Marieke van Stalborch, Aafke de Ligt, Mark Hoogenboezem, Simon Tol, Jos van Rijssel, Robert Szulcek, Harm Jan Bogaard, Patrick Hofmann, Reinier Boon, Manfred Radmacher, Vivian de Waard, Stephan Huveneers, Jaap D. van Buul
Publikováno v:
Cell Reports, Vol 24, Iss 12, Pp 3115-3124 (2018)
Summary: Leukocytes follow the well-defined steps of rolling, spreading, and crawling prior to diapedesis through endothelial cells (ECs). We found increased expression of DLC-1 in stiffness-associated diseases like atherosclerosis and pulmonary arte
Externí odkaz:
https://doaj.org/article/5f17c77e78704ee38964331f2e1d6ba9
Autor:
Niels Heemskerk, Lilian Schimmel, Chantal Oort, Jos van Rijssel, Taofei Yin, Bin Ma, Jakobus van Unen, Bettina Pitter, Stephan Huveneers, Joachim Goedhart, Yi Wu, Eloi Montanez, Abigail Woodfin, Jaap D. van Buul
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-17 (2016)
Endothelial cells can support leukocyte extravasation without causing vascular leakage, but the exact mechanism underlying this process has not been fully elucidated. Here the authors show that it is regulated through actomyosin-based endothelial por
Externí odkaz:
https://doaj.org/article/6c3133e60cd84e1f9874b018a721bd0a
Autor:
Yi Jin, Yindi Ding, Mark Richards, Mika Kaakinen, Wolfgang Giese, Elisabeth Baumann, Anna Szymborska, André Rosa, Sofia Nordling, Lilian Schimmel, Emir Bora Akmeriç, Andreia Pena, Emmanuel Nwadozi, Maria Jamalpour, Katrin Holstein, Miguel Sáinz-Jaspeado, Miguel O. Bernabeu, Michael Welsh, Emma Gordon, Claudio A. Franco, Dietmar Vestweber, Lauri Eklund, Holger Gerhardt, Lena Claesson-Welsh
Publikováno v:
Nature Cardiovascular Research. 1:1156-1173
Vascular endothelial (VE)-cadherin in endothelial adherens junctions is an essential component of the vascular barrier, critical for tissue homeostasis and implicated in diseases such as cancer and retinopathies. Inhibitors of Src cytoplasmic tyrosin
Autor:
Emma Gordon, Eike K. Mahlandt, Jos van Rijssel, Mark R. Winter, Simon Tol, Ivar Noordstra, Marten Postma, Janine J. G. Arts, Abraham C.I. van Steen, Eric Wait, Joachim Goedhart, Martijn A. Nolte, Eloi Montanez, Lilian Schimmel, Teng Leong Chew, Max L. B. Grönloh, Satya Khuon, John M. Heddleston, Jaap D. van Buul, Barbara Walzog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bdded14cdd1b0df3a8cabaf8ffe889c
https://doi.org/10.7554/elife.66074.sa2
https://doi.org/10.7554/elife.66074.sa2
Autor:
Simon Tol, John M. Heddleston, Barbara Walzog, Eric Wait, Ivar Noordstra, Eloi Montanez, Marten Postma, Abraham C.I. van Steen, Joachim Goedhart, Lilian Schimmel, Martijn A. Nolte, Teng-Leong Chew, Mark R. Winter, Emma Gordon, Eike K. Mahlandt, Jos van Rijssel, Max L. B. Grönloh, Janine J. G. Arts, Jaap D. van Buul, Satya Khuon
Publikováno v:
eLife, Vol 10 (2021)
eLife, 10:e66074. eLife Sciences Publications
Dipòsit Digital de la UB
Universidad de Barcelona
eLife
eLife, 10:e66074. eLife Sciences Publications
Dipòsit Digital de la UB
Universidad de Barcelona
eLife
Upon inflammation, leukocytes rapidly transmigrate across the endothelium to enter the inflamed tissue. Evidence accumulates that leukocytes use preferred exit sites, alhough it is not yet clear how these hotspots in the endothelium are defined and h
Autor:
Ivar Noordstra, Mario Díez Hermoso, Lilian Schimmel, Alexis Bonfim-Melo, Denni Currin-Ross, Cao Nguyen Duong, Joseph Mathew Kalappurakkal, Richard G. Morris, Dietmar Vestweber, Satyajit Mayor, Emma Gordon, Pere Roca Cusachs, Alpha S. Yap
SUMMARYAdherens junctions allow cell contact to inhibit epithelial migration. But a long-standing puzzle is how locomotion is downregulated when E-cadherin adhesions form at surfaces perpendicular, but not those parallel, to the direction of migratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::587f6b28a54aec53a75b03878d91e2c1
https://doi.org/10.1101/2021.07.28.454239
https://doi.org/10.1101/2021.07.28.454239