Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Lilian Hernandez-Alvarez"'
Intramolecular Interactions Enhance the Potency of Gallinamide A Analogues against Trypanosoma cruzi
Autor:
Elany Barbosa Da Silva, Vandna Sharma, Lilian Hernandez-Alvarez, Arthur H. Tang, Alexander Stoye, Anthony J. O’Donoghue, William H. Gerwick, Richard J. Payne, James H. McKerrow, Larissa M. Podust
Publikováno v:
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Made available in DSpace on 2022-04-29T08:40:33Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-03-10 Gallinamide A, a metabolite of the marine cyanobacterium Schizothrix sp., selectively inhibits cathepsin L-like cysteine proteases. We evalua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cdb5fecb14e1c1a13eb99c8c001679f
Autor:
Elany, Barbosa Da Silva, Vandna, Sharma, Lilian, Hernandez-Alvarez, Arthur H, Tang, Alexander, Stoye, Anthony J, O'Donoghue, William H, Gerwick, Richard J, Payne, James H, McKerrow, Larissa M, Podust
Publikováno v:
Journal of medicinal chemistry. 65(5)
Gallinamide A, a metabolite of the marine cyanobacterium
Autor:
Elany Barbosa Da Silva, Vandna Sharma, Lilian Hernandez-Alvarez, Arthur H. Tang, Alexander Stoye, Anthony J. O’Donoghue, William H. Gerwick, Richard J. Payne, James H. McKerrow, Larissa M. Podust
Gallinamide A, a metabolite of the marine cyanobacterium Schizothrix sp., selectively inhibits cathepsin L-like cysteine proteases. We evaluated potency of gallinamide A and 23 synthetic analogs against intracellular Trypanosoma cruzi amastigotes and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f77475f716d1b751ccf5823a16a0a16e
https://doi.org/10.1101/2021.12.22.473926
https://doi.org/10.1101/2021.12.22.473926
Publikováno v:
Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Made available in DSpace on 2021-06-25T11:45:18Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-12-01 University of California San Diego University of California San Diego Center for Tropical Diseases fund University of California San Diego Ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06f471cc1dcbbd302a1d02dd8d5f1129
Publikováno v:
Mol Pharmacol
Cytochromes P450 (P450, CYP) metabolize a wide variety of endogenous and exogenous lipophilic molecules, including most drugs. Sterol 14α-demethylase (CYP51) is a target for antifungal drugs known as conazoles. Using X-ray crystallography, we have d
Autor:
Dany Naranjo-Feliciano, Heidy Díaz de Arce, Lester J. Pérez, Orlando Martínez-Pérez, Lilian Hernandez-Alvarez, Llilianne Ganges, Liani Coronado, José I. Núñez, Carmen L. Perera, Liliam Rios
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-18 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-18 (2017)
Classical swine fever (CSF) is one of the most important infectious diseases causing significant economic losses. Its causal agent, CSF virus (CSFV), is a member of the Pestivirus genus included into the Flaviviridae family. Previous molecular epidem
Autor:
Lilian Hernández-Alvarez, Antonio B Oliveira Jr, Jorge Enrique Hernández-González, Jorge Chahine, Pedro Geraldo Pascutti, Alexandre Suman de Araujo, Fátima Pereira de Souza
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 2027-2044 (2021)
During their life cycle, Leishmania parasites display a fine-tuned regulation of the mRNA translation through the differential expression of isoforms of eukaryotic translation initiation factor 4E (LeishIF4Es). The interaction between allosteric modu
Externí odkaz:
https://doaj.org/article/6ead92ed6d4f49e786c537950ff4a455