Intratubular germ cell neoplasia of unclassified type occupying the whole testis accompanied by a small mature teratoma and metastatic choriocarcinoma and Sertoli cell-only tubules in the other testis

Autor: Riruke Maruyama, Takayuki Harada, Akinobu Nakano, Cem Sezer, Masaaki Iijima, Asuka Araki, Li Zhou, Liliam L. Pineda, Manabu Yoshida

Publikováno v: Pathology International. 53:726-732

A 19-year-old man with mild mental retardation was diagnosed as having metastatic choriocarcinoma and a testicular tumor. Histopathological examination of the resected testis revealed the presence of a small lesion of mature teratoma but no trace of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::65636e936cc2b2eadf136b686d02a7ec
https://doi.org/10.1046/j.1440-1827.2003.01533.x

Ataxia and male sterility (AMS) mouse. A new genetic variant exhibiting degeneration and loss of cerebellar Purkinje cells and spermatic cells

Autor: Masaaki Iijima, Minesuke Yokoyama, Koji Omura, Takayuki Harada, Liliam L. Pineda, Li Zhou, Akinobu Nakano, Yoji Yamasaki

Publikováno v: Pathology International. 53:382-389

We describe a novel genetic variant mouse that exhibited ataxia and male sterility, named the AMS mouse. It arose in autoimmune-prone MRL/lpr strain and putative ams mutation showed an autosomal recessive inheritance pattern. Clinical symptoms were f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba63fdf42338098b5c9fc46bd6dd2698
https://doi.org/10.1046/j.1440-1827.2003.01485.x

Branch Retinal Artery Occlusion Caused by an Embolus of Metastatic Gastric Adenocarcinoma

Autor: Hisashi Masuda, Takayuki Harada, Taiji Takanashi, Liliam L. Pineda, Akihiro Ohira, Yuzo Shibuya

Publikováno v: Scopus-Elsevier

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61f5cf4e3c1c5286bd09695bb6f14178
https://doi.org/10.1001/archopht.120.9.1209

Industry Review of Best Practices for Risk Management of Drug-Induced Liver Injury from Development to Real-World Use.

Autor: Marquez L; Janssen Research and Development, LLC, Raritan, NJ, USA. lmarquez@its.jnj.com., Raheja R; AbbVie, North Chicago, IL, USA., Chan-Liston M; Bristol Myers Squibb, Lawrenceville, NJ, USA., Marcinak J; AbbVie, North Chicago, IL, USA., Estilo A; Otsuka Pharmaceutical Development, Inc. (OPDC), Princeton, NJ, USA., Pineda Salgado L; Otsuka Pharmaceutical Development, Inc. (OPDC), Princeton, NJ, USA., Jiang J; Daiichi Sankyo, Inc., Basking Ridge, NJ, USA., Chang C; Takeda, Cambridge, MA, USA., Beninger P; Public Health and Community Medicine, Tufts University School of Medicine, 136 Harrison Avenue, Boston, MA, 02111, USA.

Publikováno v: Drug safety [Drug Saf] 2024 Jan; Vol. 47 (1), pp. 1-22. Date of Electronic Publication: 2023 Oct 24.

Overview of Causality Assessment for Drug-Induced Liver Injury (DILI) in Clinical Trials.

Autor: Hey-Hadavi J; Pfizer, 235 E 42nd Street, New York City, NY, 10017, USA. Judith.Hey-Hadavi@pfizer.com., Seekins D; Bristol-Myers Squibb, Lawrenceville, NJ, USA., Palmer M; Takeda, Cambridge, MA, USA.; Liver Consulting LLC, New York City, USA., Coffey D; Bristol-Myers Squibb, Lawrenceville, NJ, USA., Caminis J; Sanofi, Bridgewater, NJ, USA., Abdullaev S; Bristol-Myers Squibb, Lawrenceville, NJ, USA., Patwardhan M; AbbVie, North Chicago, IL, USA., Tyler H; Otsuka Pharmaceutical Development and Commercialization, Inc., 508 Carnegie Center Dr, Princeton, NJ, 08540, USA., Raheja R; AbbVie, North Chicago, IL, USA., Stanley AM; IQ DILI Consortium, Washington, DC, USA., Pineda-Salgado L; Otsuka Pharmaceutical Development and Commercialization, Inc., 508 Carnegie Center Dr, Princeton, NJ, 08540, USA., Bourdet DL; Theravance Biopharma, South San Francisco, CA, USA., Andrade RJ; Unidad de Gestión Clínica de Aparato Digestivo, Instituto de Investigación Biomédica de Málaga-IBIMA, Hospital Universitario Virgen de la Victoria, Universidad de Málaga, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBERehd, Málaga, Spain., Hayashi PH; University of North Carolina, Chapel Hill, NC, USA., Dimick-Santos L; US Food and Drug Administration, Silver Spring, MD, USA., Rockey DC; Medical University of South Carolina, Charleston, SC, USA., Estilo A; Otsuka Pharmaceutical Development and Commercialization, Inc., 508 Carnegie Center Dr, Princeton, NJ, 08540, USA. Alvin.Estilo@otsuka-us.com.

Publikováno v: Drug safety [Drug Saf] 2021 Jun; Vol. 44 (6), pp. 619-634. Date of Electronic Publication: 2021 Mar 16.