Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Lilia Marinova‐Mutafchieva"'
Autor:
Marc Feldmann, Richard O. Williams, Lilia Marinova-Mutafchieva, Ravinder N. Maini, Lesley J. Mason, Claudia Mauri, Susan E. Ross
Objective. To define the mechanisms of action of 2 novel drugs, cyclosporine and anti-tumor necrosis factor alpha (TNF alpha), in collagen-induced arthritis and to determine the effect of combination therapy.Methods. Type II collagen-immunized DBA/1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4b5987a26dc0a7a2b200e42c0e41bb2
https://doi.org/10.1002/1529-0131(199810)41:10<1806::aid-art12>3.0.co
https://doi.org/10.1002/1529-0131(199810)41:10<1806::aid-art12>3.0.co
Autor:
Lilia Marinova-Mutafchieva, K Funa, Nathan J. Zvaifler, Ravinder N. Maini, Richard O. Williams
Objective To determine the involvement of mesenchymal progenitor cells in the induction of collagen-induced arthritis (CIA). Methods DBA/1 mice were immunized with type II collagen in adjuvant or adjuvant alone, and the presence of mesenchymal cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba916ba76c8249b0efc23af890b3468
https://ora.ox.ac.uk/objects/uuid:d6e19d31-3dff-4e47-9f2a-2f9375466dbd
https://ora.ox.ac.uk/objects/uuid:d6e19d31-3dff-4e47-9f2a-2f9375466dbd
Autor:
Lauren Broom, David T. Dexter, Lilia Marinova-Mutafchieva, Andrew D. Medhurst, John B. Davis, Mona Sadeghian
Publikováno v:
Journal of Neurochemistry. 110:966-975
Cellular interactions between activated microglia and degenerating neurons in in vivo models of Parkinson's disease are not well defined. This time course study assesses the dynamics of morphological and immunophenotypic properties of activated micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e10311ce28cbf2cfd5ec4f054e68512d
https://doi.org/10.1111/j.1471-4159.2009.06189.x
https://doi.org/10.1111/j.1471-4159.2009.06189.x
Publikováno v:
Clinical and Experimental Immunology. 146:287-293
Summary Immunization of genetically susceptible strains of mice with heterologous type II collagen leads to the induction of a self-limiting polyarthritis that begins to subside around 10 days after onset of clinical disease. The aims of this study w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaa86369c1dfb695b70dc7af205853e9
https://doi.org/10.1111/j.1365-2249.2006.03204.x
https://doi.org/10.1111/j.1365-2249.2006.03204.x
Constraints on the Efficacy of Mucosal Tolerance in Treatment of Human and Animal Arthritic Diseases
Autor:
Norman A. Staines, Lilia Marinova‐Mutafchieva, John J. Murphy, Catherine J. Derry, D. Huw Davies, Nadira Ali
Publikováno v:
Annals of the New York Academy of Sciences. 1029:250-259
Mucosal administration of an autoantigen has been shown to be a powerful way of inducing tolerance in both animal and human arthritis clinical trials. Bovine or chicken type II collagen has been administered orally to rheumatoid arthritis patients, r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccd02c6a597dcf4cb5900424ce23d240
https://doi.org/10.1196/annals.1309.056
https://doi.org/10.1196/annals.1309.056
Publikováno v:
The Journal of Immunology. 165:7240-7245
We have evaluated the effects of anti-TNF-alpha, anti-IL-1, and combined anti-TNF-alpha/anti-CD4 therapy in collagen-induced arthritis. Blockade of TNF-alpha or IL-1 before disease onset delayed, but did not prevent, the induction of arthritis. When
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54987508984f522792d00c6b465e8a2c
https://doi.org/10.4049/jimmunol.165.12.7240
https://doi.org/10.4049/jimmunol.165.12.7240
Autor:
Anne-Marie Malfait, Angela S. Malik, Lilia Marinova-Mutafchieva, Debra M. Butler, Ravinder N. Maini, Marc Feldmann
Publikováno v:
The Journal of Immunology. 162:6278-6283
The therapeutic potential of salbutamol, a β2-adrenergic agonist, was explored in collagen-induced arthritis. This study was based on a report that salbutamol, by elevating intracellular cAMP, inhibits IL-12 production by macrophages and dendritic c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9abff2a339ff338d49c56ba7911c7a8
https://doi.org/10.4049/jimmunol.162.10.6278
https://doi.org/10.4049/jimmunol.162.10.6278
Autor:
Maria-Jesus Sanz, Lilia Marinova-Mutafchieva, Patricia Green, Roy R. Lobb, Marc Feldmann, Sussan Nourshargh
Publikováno v:
The Journal of Immunology. 160:5637-5645
IL-4 has been implicated in the pathogenesis of a number of allergic inflammatory disease states where the accumulation of eosinophils is a prominant feature. The aim of the present study was to use an isotopic in vivo model to investigate the abilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b18b764d3151e0b61f5dce8efd986570
https://doi.org/10.4049/jimmunol.160.11.5637
https://doi.org/10.4049/jimmunol.160.11.5637
Autor:
David T. Dexter, Lilia Marinova-Mutafchieva, Mona Sadeghian, John B. Davis, Andrew D. Medhurst, Lauren Broom
Publikováno v:
Free radical biologymedicine. 50(5)
Neuroinflammation and the activation of inducible nitric oxide synthase (iNOS) have been proposed to play a role in the pathogenesis of Parkinson disease (PD). In this study we investigated the effects of the selective iNOS inhibitor GW274150 in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8f05a027fa9a3d9cf83bb7f71ed0cbe
https://pubmed.ncbi.nlm.nih.gov/21185368
https://pubmed.ncbi.nlm.nih.gov/21185368
Autor:
David T. Dexter, Mona Sadeghian, David Virley, John B. Davis, Lilia Marinova-Mutafchieva, Andrew D. Medhurst, Lauren Broom
Publikováno v:
Journal of neuroimmunology. 246(1-2)
Background Peroxisome proliferator-activated receptor gamma (PPARγ) is a nuclear hormone receptor that has been shown to have anti-inflammatory and matrix metalloproteinase (MMP) inhibitor properties. PPARγ agonists have been shown to have neuropro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbe02485ea3100c704dfed824c5ef6b7
https://pubmed.ncbi.nlm.nih.gov/22498097
https://pubmed.ncbi.nlm.nih.gov/22498097