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pro vyhledávání: '"Lilia Brown"'
Autor:
James Lally, Christian Marinaccio, Lilia Brown, Vincenzo Martinelli, Vishaka Sovani, Ciro Roberto Rinaldi, Ciaren Graham, Kristian Boasman, John D. Crispino, Ilaria Cappuccio
Publikováno v:
Lally, J, Brown, L, Martinelli, V, Cappuccio, I, Sovani, V, Marinaccio, C, Crispino, J D, Graham, C, Rinaldi, C & Boasman, K 2019, ' GATA-1 a potential novel biomarker for the differentiation of essential thrombocythaemia and myelofibrosis ', Journal of Thrombosis and Haemostasis . https://doi.org/10.1111/jth.14433
Essentials The BCR-ABL negative myeloproliferative neoplasms are subjected to unknown phenotypic modifiers. GATA-1 is upregulated in ET patients, regardless of treatment regimen or mutational status. Myelofibrosis (MF) megakaryocytes displayed decrea
Publikováno v:
Blood. 124:5581-5581
Somatic mutations in exon 9 of calreticulin (CALR) gene were recently discovered in patients with essential thrombocythemia (ET) and primary myelofibrosis (PMF) lacking JAK2 and MPL mutations, and absent in patient with polycythemia vera (PV). Among
Publikováno v:
Blood. 124:5574-5574
GATA1 is the founding member of the GATA transcription factor family and is essential for cell maturation and differentiation within the erythroid and megakaryocytic lineages. GATA1 is a pleotropic transcription factor, whose expression is essential