Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Lili K Doerfel"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Animal mitochondrial gene expression relies on specific interactions between nuclear-encoded aminoacyl-tRNA synthetases and mitochondria-encoded tRNAs. Their evolution involves an antagonistic interplay between strong mutation pressure on mt
Externí odkaz:
https://doaj.org/article/1927bea390454aeb94586ab2d058d497
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Mitochondrial tRNAs are indispensable and yet underwent an extreme mutational erosion. The authors report the structures of a mitochondrial aaRS-tRNA complex and show how the most degenerated of all human mtRNAs is recognized by its cognate synthetas
Externí odkaz:
https://doaj.org/article/c61de2c5906644379fa90b8007176bd0
Autor:
Xiyu Dong, Lili K Doerfel, Kai Sheng, Jessica N Rabuck-Gibbons, Anna M Popova, Dmitry Lyumkis, James R Williamson
Publikováno v:
Nucleic Acids Research. 51:2862-2876
Understanding the assembly principles of biological macromolecular complexes remains a significant challenge, due to the complexity of the systems and the difficulties in developing experimental approaches. As a ribonucleoprotein complex, the ribosom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::668e953df05b4872a54ed4e2d23a1ec8
https://doi.org/10.1093/nar/gkad082
https://doi.org/10.1093/nar/gkad082
Autor:
Xiyu Dong, Lili K. Doerfel, Kai Sheng, Jessica N. Rabuck-Gibbons, Anna M. Popova, Dmitry Lyumkis, James R. Williamson
Understanding the assembly principles of biological macromolecular complexes remains a significant challenge, due to the complexity of the systems and the difficulties in developing experimental approaches. As a ribonucleoprotein complex, the ribosom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acc5c849c99ecf3e4c7b322095228595
https://doi.org/10.1101/2022.11.09.515862
https://doi.org/10.1101/2022.11.09.515862
Autor:
Marina V. Rodnina, Lili K. Doerfel, Daniel N. Wilson, Ingo Wohlgemuth, Vladimir Kubyshkin, Nediljko Budisa, Agata L. Starosta
Publikováno v:
Journal of the American Chemical Society
The peptide bond formation with the amino acid proline (Pro) on the ribosome is slow, resulting in translational stalling when several Pro have to be incorporated into the peptide. Stalling at poly-Pro motifs is alleviated by the elongation factor P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90b5bc6265724ca9fac28ec3abe65561
https://doi.org/10.1021/jacs.5b07427
https://doi.org/10.1021/jacs.5b07427
Autor:
Lili K. Doerfel, Marina V. Rodnina
Publikováno v:
Biopolymers. 99:837-845
The elongation phase of translation is promoted by three universal elongation factors, EF-Tu, EF-Ts, and EF-G in bacteria and their homologs in archaea and eukaryotes. Recent findings demonstrate that the translation of a subset of mRNAs requires a f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd52cbc26f818b13219327a88e4ce9d9
https://doi.org/10.1002/bip.22341
https://doi.org/10.1002/bip.22341
Autor:
Lili K. Doerfel, Ingo Wohlgemuth, Henning Urlaub, Marina V. Rodnina, Christina Kothe, Frank Peske
Publikováno v:
Science
Translating Polyproline Translation of messenger RNA into protein is carried out by the ribosome, together with a variety of accessory factors, which offer the potential for regulation of this critical step in gene expression (see the Perspective by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1f519969d766630c752c12c1c1efa02
https://doi.org/10.1126/science.1229017
https://doi.org/10.1126/science.1229017