Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Lilei Xu"'
Autor:
Lilei Xu, Jiaqi Ma, Chuanlong Zhou, Zhe Shen, Kean Zhu, Xuewen Wu, Yang Chen, Ting Chen, Xianming Lin
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Knee osteoarthritis (KOA) is a common chronic joint disease globally. Synovial inflammation plays a pivotal role in its pathogenesis, preceding cartilage damage. Identifying biomarkers in osteoarthritic synovial tissues holds promise for ear
Externí odkaz:
https://doaj.org/article/9eafdbdfc06c48d8a0e95ff08b457ddf
Evidence supported by Mendelian randomization: impact on inflammatory factors in knee osteoarthritis
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
BackgroundPrior investigations have indicated associations between Knee Osteoarthritis (KOA) and certain inflammatory cytokines, such as the interleukin series and tumor necrosis factor-alpha (TNFα). To further elaborate on these findings, our inves
Externí odkaz:
https://doaj.org/article/86d71e7a946c446ea02c0b74771ecaf1
Autor:
Jie Deng, Xianyang Fang, Lin Huang, Shanshan Li, Lilei Xu, Keqiong Ye, Jinsong Zhang, Kaiming Zhang, Qiangfeng Cliff Zhang
Publikováno v:
Fundamental Research, Vol 3, Iss 5, Pp 727-737 (2023)
RNA molecules serve a wide range of functions that are closely linked to their structures. The basic structural units of RNA consist of single- and double-stranded regions. In order to carry out advanced functions such as catalysis and ligand binding
Externí odkaz:
https://doaj.org/article/4828766ef7204c199ec89812e92426df
Autor:
Xiaolin Niu, Qiuhan Liu, Zhonghe Xu, Zhifeng Chen, Linghui Xu, Lilei Xu, Jinghong Li, Xianyang Fang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The xrRNA1 RNA from ZIKA virus (ZIKV) forms a complex ring-like architecture and is known for its mechanical anisotropy, but the mechanism for its direction-dependent mechanical responses remain unclear. Here authors use a single-molecule nanopore se
Externí odkaz:
https://doaj.org/article/ddddac9742724272becb5170dabf6c4a
Publikováno v:
Nucleic Acids Research. 51:952-965
In bacteria, expression of folate-related genes is controlled by the tetrahydrofolate (THF) riboswitch in response to specific binding of THF and its derivatives. Recently, a second class of THF riboswitches, named THF-II, was identified in Gram-nega
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6977c819997638ba9cfa4ac4a9bd269
https://doi.org/10.1093/nar/gkac1257
https://doi.org/10.1093/nar/gkac1257
Autor:
Yanping Hu, Yan Wang, Jaideep Singh, Ruirui Sun, Lilei Xu, Xiaolin Niu, Keyun Huang, Guangcan Bai, Guoquan Liu, Xiaobing Zuo, Chunlai Chen, Peter Z. Qin, Xianyang Fang
Publikováno v:
ACS Chemical Biology. 17:2448-2460
Pulsed electron-electron double resonance (PELDOR) spectroscopy, X-ray scattering interferometry (XSI), and single-molecule Förster resonance energy transfer (smFRET) are molecular rulers that provide inter- or intramolecular pair-wise distance dist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::394d370285d8073ba36ab09d52fce32e
https://doi.org/10.1021/acschembio.2c00199
https://doi.org/10.1021/acschembio.2c00199
Autor:
Qiuhan Liu, Xianyang Fang, Xiaolin Niu, Jinghong Li, Zhifeng Chen, Zhonghe Xu, Lilei Xu, Linghui Xu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Nature Communications
Mechanical anisotropy is an essential property for many biomolecules to assume their structures, functions and applications, however, the mechanisms for their direction-dependent mechanical responses remain elusive. Herein, by using a single-molecule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ee32bd9fc5f3fba78d0fd54102baaa2
https://doaj.org/article/ddddac9742724272becb5170dabf6c4a
https://doaj.org/article/ddddac9742724272becb5170dabf6c4a
Autor:
Jingwen Li, Lanxin Xiang, Qian Wang, Xuqian Ma, Xin Chen, Yuankui Zhu, Yaxi Yang, Le Huang, Huixia He, Lilei Xu, Xinjun Liang, Shuang Dong, Sheng Hu, Hanjie Li, Mingqian Feng
Publikováno v:
Journal of Cancer. 13(4)
Glypican-3 (GPC3) has become a compelling target for immunotherapy of hepatocellular carcinoma, including antibody-drug conjugate (ADC), and ADC-like immunotoxin. To investigate the impact of epitopes on the potency of ADCs, current study generated a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9d839fb7d89563fdbea8b7f46865d69
https://pubmed.ncbi.nlm.nih.gov/35281879
https://pubmed.ncbi.nlm.nih.gov/35281879
Autor:
Xiao Liu, Davide Proserpio, Dokyun Lee, Tong Guo, Lilei Xu, Hema Yoganarasimhan, Kanishka Misra, Jay Hauser, Eric M. Schwartz, Artem Timoshenko, Alex Burnap, Randall A. Lewis, Tomomichi Amano
Publikováno v:
Springer US
Machine learning is bringing us self-driving cars, medical diagnoses, and language translation, but how can machine learning help marketers improve marketing decisions? Machine learning models predict extremely well, are scalable to “big data,” a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d72d069e94a64ac86497d4e6916ea65
https://hdl.handle.net/1721.1/131935
https://hdl.handle.net/1721.1/131935
Autor:
Lilei Xu, Shawn Cole
China Life must decide whether to accept the government's'invitation'to develop a microinsurance product for the rural poor. Can it be done profitably?