Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Lilan Ling"'
Autor:
Sandra P. D’Angelo, Allison L. Richards, Anthony P. Conley, Hyung Jun Woo, Mark A. Dickson, Mrinal Gounder, Ciara Kelly, Mary Louise Keohan, Sujana Movva, Katherine Thornton, Evan Rosenbaum, Ping Chi, Benjamin Nacev, Jason E. Chan, Emily K. Slotkin, Hannah Kiesler, Travis Adamson, Lilan Ling, Pavitra Rao, Shreyaskumar Patel, Jonathan A. Livingston, Samuel Singer, Narasimhan P. Agaram, Cristina R. Antonescu, Andrew Koff, Joseph P. Erinjeri, Sinchun Hwang, Li-Xuan Qin, Mark T. A. Donoghue, William D. Tap
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
The activity of PD-1 blockade in patients with sarcoma has been modest so far. Here, the authors report the results of a pilot clinical trial to assess the efficacy and safety of bempegaldesleukin, a CD122-preferential interleukin-2 (IL-2) pathway ag
Externí odkaz:
https://doaj.org/article/b6788f9bd032450d95559d4440fb175b
Autor:
Matthew Magruder, Adam N. Sholi, Catherine Gong, Lisa Zhang, Emmanuel Edusei, Jennifer Huang, Shady Albakry, Michael J. Satlin, Lars F. Westblade, Carl Crawford, Darshana M. Dadhania, Michelle Lubetzky, Ying Taur, Eric Littman, Lilan Ling, Philip Burnham, Iwijn De Vlaminck, Eric Pamer, Manikkam Suthanthiran, John Richard Lee
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Urinary tract infections (UTIs) are associated with changes in the gut microbiome. Here, the authors evaluate the relationship between the gut microbiome and development of UTI in kidney transplant patients and show that uropathogenic gut abundance m
Externí odkaz:
https://doaj.org/article/d088df94103146f19b31b48d5e6102c7
Autor:
Matthew J. Pianko, Sean M. Devlin, Eric R. Littmann, Aisara Chansakul, Donna Mastey, Meghan Salcedo, Emily Fontana, Lilan Ling, Elizabet Tavitian, John B. Slingerland, Ann E. Slingerland, Annelie Clurman, Antonio L.C. Gomes, Ying Taur, Eric G. Pamer, Jonathan U. Peled, Marcel R.M. van den Brink, Ola Landgren, Alexander M. Lesokhin
Publikováno v:
Blood Advances, Vol 3, Iss 13, Pp 2040-2044 (2019)
Abstract: Patients with multiple myeloma (MM) who achieve minimal residual disease (MRD) negativity after upfront treatment have superior outcomes compared with those who remain MRD+. Recently, associations have been shown between specific commensal
Externí odkaz:
https://doaj.org/article/9883a042db834c8a806f8895e5db5018
Autor:
Hea-Jin Jung, Eric R. Littmann, Ruth Seok, Ingrid M. Leiner, Ying Taur, Jonathan Peled, Marcel van den Brink, Lilan Ling, Liang Chen, Barry N. Kreiswirth, Andrew L. Goodman, Eric G. Pamer
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
ABSTRACT A diverse, antibiotic-naive microbiota prevents highly antibiotic-resistant microbes, including carbapenem-resistant Klebsiella pneumoniae (CR-Kp), from achieving dense colonization of the intestinal lumen. Antibiotic-mediated destruction of
Externí odkaz:
https://doaj.org/article/726e360e4c7f4b5f9deb969444709486
Autor:
Krista Dubin, Margaret K. Callahan, Boyu Ren, Raya Khanin, Agnes Viale, Lilan Ling, Daniel No, Asia Gobourne, Eric Littmann, Curtis Huttenhower, Eric G. Pamer, Jedd D. Wolchok
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
A subset of cancer patients treated with immune checkpoint blockade develops colitis. Here the authors show that lower abundance of Bacteroidetes and vitamin B biosynthetic modules in fecal samples of melanoma patients can predict their susceptibilit
Externí odkaz:
https://doaj.org/article/4fd307aaea2d42b5882a076b1df4053e
Autor:
Brittany B. Lewis, Rebecca A. Carter, Lilan Ling, Ingrid Leiner, Ying Taur, Mini Kamboj, Erik R. Dubberke, Joao Xavier, Eric G. Pamer
Publikováno v:
mBio, Vol 8, Iss 4 (2017)
ABSTRACT Clostridium difficile is a spore-forming anaerobic bacterium that causes colitis in patients with disrupted colonic microbiota. While some individuals are asymptomatic C. difficile carriers, symptomatic disease ranges from mild diarrhea to p
Externí odkaz:
https://doaj.org/article/9c54828146554dea95310db8ae19f8c7
Autor:
Silvia Caballero, Rebecca Carter, Xu Ke, Bože Sušac, Ingrid M Leiner, Grace J Kim, Liza Miller, Lilan Ling, Katia Manova, Eric G Pamer
Publikováno v:
PLoS Pathogens, Vol 11, Iss 9, p e1005132 (2015)
Antibiotic resistance among enterococci and γ-proteobacteria is an increasing problem in healthcare settings. Dense colonization of the gut by antibiotic-resistant bacteria facilitates their spread between patients and also leads to bloodstream and
Externí odkaz:
https://doaj.org/article/c90248a7d57c4f5998539260ad202d32
Autor:
John R Lee, Thangamani Muthukumar, Darshana Dadhania, Ying Taur, Robert R Jenq, Nora C Toussaint, Lilan Ling, Eric Pamer, Manikkam Suthanthiran
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0122399 (2015)
Tacrolimus dosing to establish therapeutic levels in recipients of organ transplants is a challenging task because of much interpatient and intrapatient variability in drug absorption, metabolism, and disposition. In view of the reported impact of gu
Externí odkaz:
https://doaj.org/article/05d785d5ef4d43e7a5343958f6c9e583
Autor:
Andrew J. Dannenberg, Eric G. Pamer, Robert Benezra, Lilan Ling, Chen S. Suen, Edward D. Karoly, Nitai D. Leve, Steven S. Gross, Rhonda K. Yantiss, Erika Sue, Erin M. McNally, Xi Kathy Zhou, David C. Montrose
Treatment with celecoxib, a selective COX-2 inhibitor, reduces formation of premalignant adenomatous polyps in the gastrointestinal tracts of humans and mice. In addition to its chemopreventive activity, celecoxib can exhibit antimicrobial activity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae7ff1d318327c29025450d37c74f90a
https://doi.org/10.1158/1940-6207.c.6547562.v1
https://doi.org/10.1158/1940-6207.c.6547562.v1
Autor:
Andrew J. Dannenberg, Eric G. Pamer, Robert Benezra, Lilan Ling, Chen S. Suen, Edward D. Karoly, Nitai D. Leve, Steven S. Gross, Rhonda K. Yantiss, Erika Sue, Erin M. McNally, Xi Kathy Zhou, David C. Montrose
Pathway alterations associated with celecoxib-induced metabolite changes in WT mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1efcd768ccff6008d8f7e1918d0540f0
https://doi.org/10.1158/1940-6207.22534586
https://doi.org/10.1158/1940-6207.22534586