Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Lilach Chen"'
Autor:
Lilach Chen, Igor Nudelman, Jonathan B. Spencer, El-Habib Sahraoui, Marina Cherniavsky, Timor Baasov, Nicholas M. Llewellyn
Publikováno v:
Advanced Synthesis & Catalysis. 350:1682-1688
A series of unprotected pseudo-disaccharides and pseudo-trisaccharides of 2-deoxystreptamine-containing aminoglycosides have been selectively acylated at the N-1 position with the valuable (S)-4-amino-2-hydroxybutanoyl (AHB) pharmacophore by using th
Publikováno v:
Bioorganicmedicinal chemistry. 16(19)
A new pseudo-disaccharide NB23 with a 3',4'-methylidene protection was designed and its properties were evaluated in comparison to other two structurally related pseudo-disaccharides. The basicity of the 2'-amine was found to be well correlated to ac