Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lila Rieber"'
Autor:
Lila Rieber, Shaun Mahony
Publikováno v:
Epigenetics & Chromatin, Vol 12, Iss 1, Pp 1-17 (2019)
Abstract Background Comparisons of Hi–C data sets between cell types and conditions have revealed differences in topologically associated domains (TADs) and A/B compartmentalization, which are correlated with differences in gene regulation. However
Externí odkaz:
https://doaj.org/article/e6007c1551b44140b81cbac03da9477c
Autor:
Sudarshan Pinglay, Milica Bulajić, Dylan P. Rahe, Emily Huang, Ran Brosh, Nicholas E. Mamrak, Benjamin R. King, Sergei German, John A. Cadley, Lila Rieber, Nicole Easo, Timothée Lionnet, Shaun Mahony, Matthew T. Maurano, Liam J. Holt, Esteban O. Mazzoni, Jef D. Boeke
Publikováno v:
Science
INTRODUCTION: Despite an ever-expanding catalog of noncoding elements that are implicated in the control of mammalian gene expression, how the regulatory input from multiple elements is integrated across a genomic neighborhood has remained largely un
Autor:
Jef D. Boeke, Dylan P Rahe, Shaun Mahony, Nicole Easo, Sergei German, Lila Rieber, Ran Brosh, Esteban O. Mazzoni, Emily P. Huang, Sudarshan Pinglay, Liam J. Holt, Milica Bulajić, John Cadley, Matt T Maurano
PreciseHoxgene expression is crucial for embryonic patterning. Intra-Hoxtranscription factor binding and distal enhancer elements have emerged as the major regulatory modes controllingHoxgene expression. However, quantifying their relative contributi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79dc7c771ac323990d91b5b3829cda88
https://doi.org/10.1101/2021.07.07.451065
https://doi.org/10.1101/2021.07.07.451065
Few existing methods enable the visualization of relationships between regulatory genomic activities and genome organization as captured by Hi-C experimental data. Genome-wide Hi-C datasets are often displayed using “heatmap” matrices, but it is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa11f533eb528669fb93828b2e9cff86
Autor:
Matthew J. Rossi, Shaun Mahony, Bongsoo Park, Lila Rieber, Vinesh Vinayachandran, Chitvan Mittal, B. Franklin Pugh, Rohit Reja
Publikováno v:
Genome research.
Gene expression is controlled by a variety of proteins that interact with the genome. Their precise organization and mechanism of action at every promoter remains to be worked out. To better understand the physical interplay among genome-interacting
Autor:
Lila Rieber, Shaun Mahony
Publikováno v:
Bioinformatics
Motivation Recent experiments have provided Hi-C data at resolution as high as 1 kbp. However, 3D structural inference from high-resolution Hi-C datasets is often computationally unfeasible using existing methods. Results We have developed miniMDS, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f72b57739cb7701bbc5fa3160700bb1d