Intracellular lysyl oxidase: Effect of a specific inhibitor on nuclear mass in proliferating cells

Autor: Marie Torres, Lila Graham, Hao Wang, Fawzy A. Saad

Publikováno v: Biochemical and Biophysical Research Communications. 396:944-949

LOX, the principal enzyme involved in crosslinking of collagen, was the first of several lysyl oxidase isotypes to be characterized. Its active form was believed to be exclusively extracellular. Active LOX was later reported to be present in cell nuc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb1e8cce7e052f0dd8b93a9741addda7
https://doi.org/10.1016/j.bbrc.2010.05.028

Small-angle X-ray scattering study of intramuscular fish bone: collagen fibril superstructure determined from equidistant meridional reflections

Autor: Benjamin S. Hsiao, Hong-wen Zhou, Melvin J. Glimcher, Lila Graham, Christian Burger, Igors Sicŝ, Benjamin Chu

Publikováno v: Journal of Applied Crystallography. 41:252-261

New insights into the bone collagen fibril superstructure have been obtained by novel small-angle X-ray scattering analysis. The analysis was carried out on the small-angle equidistant meridional reflections resulting from the periodic structure of c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c924d8e736f419cc0198dbe69c1d3fe3
https://doi.org/10.1107/s0021889808000277

Density of organic matrix of native mineralized bone measured by water- and fat-suppressed proton projection MRI

Autor: Melvin J. Glimcher, Yaotang Wu, Yan Wang, Lila Graham, Jerome L. Ackerman, David A. Chesler

Publikováno v: Magnetic Resonance in Medicine. 50:59-68

Water- and fat-suppressed projection MR imaging (WASPI) utilizes the large difference between the proton Ts of the solid organic matrix and the fluid constituents of bone to suppress the fluid signals while preserving solid matrix signals. The solid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f59b3104dd2003bcf88c17de0383e9c
https://doi.org/10.1002/mrm.10512

A comprehensive survey of the acid-stable fluorescent cross-links formed by ribose with basic amino acids, and partial characterization of a novel Maillard cross-link

Autor: Lila Graham

Publikováno v: Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1297:9-16

Cross-linking of proteins by sugars is thought to be involved in the pathogenesis of a variety of disorders associated with diabetes and aging; however, the molecular mechanisms involved in this process are not well understood. A new, general method

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::709737b92d688c6c7fd7456f9dfeca83
https://doi.org/10.1016/0167-4838(96)00082-9

Hierarchical analysis and multi-scale modelling of rat cortical and trabecular bone

Autor: Guy Spörri, Ashkan Vaziri, Elsa Strawich, H. N. Hashemi, Juan C. Villa-Camacho, Christian Rey, Ara Nazarian, Ramin Oftadeh, Lila Graham, Hank Chiu, Henry Krigbaum, Ralph Müller, Vahid Entezari

Publikováno v: Journal of the Royal Society Interface
Journal of the Royal Society Interface, the Royal Society, 2015, vol. 12 (n° 106), pp. 1-16. ⟨10.1098/rsif.2015.0070⟩

International audience; The aim of this study was to explore the hierarchical arrangement of structural properties in cortical and trabecular bone and to determine a mathematical model that accurately predicts the tissue's mechanical properties as a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b359ea8fba4f30583827fcff381b0baf
https://doi.org/10.1098/rsif.2015.0070