Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Lik Voon, Kiew"'
Autor:
Yean Leng Loke, Adilet Beishenaliev, Pei-Wen Wang, Chung-Yin Lin, Chia-Yu Chang, Yiing Yee Foo, Farid Nazer Faruqu, Bey Fen Leo, Misni Misran, Lip Yong Chung, Dar-Bin Shieh, Lik Voon Kiew, Chia-Ching Chang, Yin Yin Teo
Publikováno v:
Ultrasonics Sonochemistry, Vol 96, Iss , Pp 106437- (2023)
Sonodynamic therapy (SDT) emerges as a promising non-invasive alternative for eradicating malignant tumours. However, its therapeutic efficacy remains limited due to the lack of sonosensitisers with high potency and biosafety. Previously, gold nanoro
Externí odkaz:
https://doaj.org/article/f473b422d7df44f9b4fec07b71a32f32
Autor:
Hui Shan Liew, Chun-Wai Mai, Mohd Zulkefeli, Thiagarajan Madheswaran, Lik Voon Kiew, Lesley Jia Wei Pua, Ling Wei Hii, Wei Meng Lim, May Lee Low
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
With less than 10% of 5-year survival rate, pancreatic ductal adenocarcinoma (PDAC) is known to be one of the most lethal types of cancer. Current literature supports that gemcitabine is the first-line treatment of PDAC. However, poor cellular penetr
Externí odkaz:
https://doaj.org/article/751ef2ab509a4f6f9c39df4b0a502749
Publikováno v:
Biosensors, Vol 11, Iss 7, p 240 (2021)
A miniature tyrosinase-based electrochemical sensing platform for label-free detection of protein tyrosine kinase activity was developed in this study. The developed miniature sensing platform can detect the substrate peptides for tyrosine kinases, s
Externí odkaz:
https://doaj.org/article/45e474d30c2e455d9f93d693f8cde2b8
Autor:
Yee Chu Kwa, Theebaa Anasamy, Yiing Yee Foo, Bey Fen Leo, Ivy Chung, Lik Voon Kiew, Lip Yong Chung
Publikováno v:
Drug Delivery Letters. 12:74-83
Background: Stattic offers a unique inhibitory effect on the STAT3 signaling pathway, a crucial mechanism in the progression of metastatic cancer. However, the development of Stattic has been impeded by its hydrophobicity and lack of specificity. To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d5ece3fe9bc4ea6ff80586fee356284
https://doi.org/10.2174/2210303112666220330115110
https://doi.org/10.2174/2210303112666220330115110
Autor:
Phei San Lai, Syed Muhammad Usama, Lik-Voon Kiew, Hong Boon Lee, Lip Yong Chung, Kevin Burgess, Chin Siang Kue
Publikováno v:
Cancer Immunology, Immunotherapy. 71:2099-2108
Conventional cancer therapies such as chemotherapy are non-selective and induce immune system anergy, which lead to serious side effects and tumor relapse. It is a challenge to prime the body's immune system in the cancer-bearing subject to produce c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a5a39803da8f35725024f5afa9580b8
https://doi.org/10.1007/s00262-022-03147-y
https://doi.org/10.1007/s00262-022-03147-y
Autor:
Hui Shan Liew, Chun-Wai Mai, Mohd Zulkefeli, Thiagarajan Madheswaran, Lik Voon Kiew, Nicolas Delsuc, May Lee Low
Publikováno v:
Molecules, Vol 25, Iss 18, p 4176 (2020)
Photodynamic therapy (PDT) is emerging as a significant complementary or alternative approach for cancer treatment. PDT drugs act as photosensitisers, which upon using appropriate wavelength light and in the presence of molecular oxygen, can lead to
Externí odkaz:
https://doaj.org/article/b07f69ccbc514ba68e7ae4d7d052c12a
Inhibition of Human Cytochrome P450 Enzymes by Bacopa monnieri Standardized Extract and Constituents
Publikováno v:
Molecules, Vol 19, Iss 2, Pp 2588-2601 (2014)
Bacopa monnieri and the constituents of this plant, especially bacosides, possess various neuropharmacological properties. Like drugs, some herbal extracts and the constituents of their extracts alter cytochrome P450 (CYP) enzymes, causing potential
Externí odkaz:
https://doaj.org/article/f42cbfd1fd5d4b25bff30e6445b5382e
Autor:
Wen Shang Saw, Theebaa Anasamy, Thu Thi Anh Do, Hong Boon Lee, Chin Fei Chee, Umit Isci, Misni Misran, Fabienne Dumoulin, Wu Yi Chong, Lik Voon Kiew, Toyoko Imae, Lip Yong Chung
Publikováno v:
Macromolecular bioscience. 22(8)
A critical factor in developing an efficient photosensitizer-gold nanoparticle (PS-AuNP) hybrid system with improved plasmonic photosensitization is to allocate a suitable space between AuNPs and PS. Poly(amidoamine) (PAMAM) dendrimer is selected as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb52fff9b23854bf8cf35fff069e2cd9
https://pubmed.ncbi.nlm.nih.gov/35579182
https://pubmed.ncbi.nlm.nih.gov/35579182
Autor:
Stephanie Sally Fong, Yiing Yee Foo, Wen Shang Saw, Bey Fen Leo, Yin Yin Teo, Ivy Chung, Boon Tong Goh, Misni Misran, Toyoko Imae, Chia-Ching Chang, Lip Yong Chung, Lik Voon Kiew
Publikováno v:
International Journal of Nanomedicine
Purpose The use of nanocarriers to improve the delivery and efficacy of antimetastatic agents is less explored when compared to cytotoxic agents. This study reports the entrapment of an antimetastatic Signal Transducer and Activator of Transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64388afb772d1be30fd89975bc2b1888
https://www.dovepress.com/chitosan-coated-plga-nanoparticles-enhance-the-antitumor-and-antimigra-peer-reviewed-fulltext-article-IJN
https://www.dovepress.com/chitosan-coated-plga-nanoparticles-enhance-the-antitumor-and-antimigra-peer-reviewed-fulltext-article-IJN
Publikováno v:
European Journal of Pharmaceutical Sciences. 181:106320
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8aa3ac2e407d8a6fce1f6b66446d02e6
https://doi.org/10.1016/j.ejps.2022.106320
https://doi.org/10.1016/j.ejps.2022.106320