Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Lijin Dong"'
Autor:
Yuhui Song, Qinying Wang, Xingshou Zhang, Lijin Dong, Shulin Bai, Dezhi Zeng, Zhi Zhang, Huali Zhang, Yuchen Xi
Publikováno v:
npj Materials Degradation, Vol 7, Iss 1, Pp 1-15 (2023)
Abstract We have employed interpretable methods to uncover the black-box model of the machine learning (ML) for predicting the maximum pitting depth (dmax) of oil and gas pipelines. Ensemble learning (EL) is found to have higher accuracy compared wit
Externí odkaz:
https://doaj.org/article/64e9e2462b034e51a8d69b901475c72a
Autor:
Sarah Pickles, Desiree Zanetti Alepuz, Yuka Koike, Mei Yue, Jimei Tong, Pinghu Liu, Yugui Zhou, Karen Jansen-West, Lillian M. Daughrity, Yuping Song, Michael DeTure, Björn Oskarsson, Neill R. Graff-Radford, Bradley F. Boeve, Ronald C. Petersen, Keith A. Josephs, Dennis W. Dickson, Michael E. Ward, Lijin Dong, Mercedes Prudencio, Casey N. Cook, Leonard Petrucelli
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Treatments for neurodegenerative disease, including Frontotemporal dementia (FTD) and Amyotrophic lateral sclerosis (ALS), remain rather limited, underscoring the need for greater mechanistic insight and disease-relevant models. Our ability to develo
Externí odkaz:
https://doaj.org/article/f5770006374045b4827be986a2b16eba
Autor:
Julian C. Lui, Jacob Wagner, Elaine Zhou, Lijin Dong, Kevin M. Barnes, Youn Hee Jee, Jeffrey Baron
Publikováno v:
JCI Insight, Vol 8, Iss 9 (2023)
Overgrowth syndromes can be caused by pathogenic genetic variants in epigenetic writers, such as DNA and histone methyltransferases. However, no overgrowth disorder has previously been ascribed to variants in a gene that acts primarily as an epigenet
Externí odkaz:
https://doaj.org/article/7cb28f5d0b99487daa54b3d5c0a7b96b
Autor:
Alexandra Bernardo-Colón, Lijin Dong, Mones Abu-Asab, Richard S. Brush, Martin-Paul Agbaga, S. Patricia Becerra
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 5, Pp 100358- (2023)
Photoreceptor cells express the patatin-like phospholipase domain-containing 2 (PNPLA2) gene that codes for pigment epithelium-derived factor receptor (PEDF-R) (also known as ATGL). PEDF-R exhibits phospholipase activity that mediates the neurotrophi
Externí odkaz:
https://doaj.org/article/e6edfbfcaeb9463cb8396dbeb2decb19
Autor:
Andrew J. Smith, Jayshree Advani, Daniel C. Brock, Jacob Nellissery, Jessica Gumerson, Lijin Dong, L. Aravind, Breandán Kennedy, Anand Swaroop
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-20 (2022)
Abstract Background Functional complexity of the eukaryotic mitochondrial proteome is augmented by independent gene acquisition from bacteria since its endosymbiotic origins. Mammalian homologs of many ancestral mitochondrial proteins have uncharacte
Externí odkaz:
https://doaj.org/article/abca2390cef14d15a89a878365c6270a
Autor:
Julian C. Lui, Adalbert Raimann, Hironori Hojo, Lijin Dong, Paul Roschger, Bijal Kikani, Uwe Wintergerst, Nadja Fratzl-Zelman, Youn Hee Jee, Gabriele Haeusler, Jeffrey Baron
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
SP7 is a transcription factor required for osteoblast differentiation and bone formation. A neomorphic mutation in SP7 was found to alter DNA binding specificity, causing a complex skeletal disorder in both mice and humans.
Externí odkaz:
https://doaj.org/article/b7d215b65ff747e8abe71813c3201ff6
Autor:
Xiaodong Jiao, Zhiwei Ma, Jingqi Lei, Pinghu Liu, Xiaoyu Cai, Pawan K. Shahi, Chi-Chao Chan, Robert Fariss, Bikash R. Pattnaik, Lijin Dong, J. Fielding Hejtmancik
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2022)
Purpose: We constructed and characterized knockout and conditional knockout mice for KCNJ13, encoding the inwardly rectifying K+ channel of the Kir superfamily Kir7.1, mutations in which cause both Snowflake Vitreoretinal Degeneration (SVD) and Retin
Externí odkaz:
https://doaj.org/article/e1616e19198b4cb4abfd674525a23606
Autor:
Zhiwei Ma, Xiaodong Jiao, Martin-Paul Agbaga, Robert E. Anderson, Haohua Qian, Qian Li, Lijin Dong, J. Fielding Hejtmancik
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13108 (2022)
Bietti crystalline corneo-retinal dystrophy (BCD) is an autosomal recessive inherited retinal dystrophy characterized by multiple shimmering yellow-white deposits in the posterior pole of the retina in association with atrophy of the retinal pigment
Externí odkaz:
https://doaj.org/article/400e2d87b7ca4b8897828fe44d44fe85
Autor:
Cheng-Rong Yu, Manoj Kumar Yadav, Minkyung Kang, Yingyos Jittayasothorn, Lijin Dong, Charles E. Egwuagu
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8156 (2022)
Interleukin-27 is constitutively secreted by microglia in the retina or brain, and upregulation of IL-27 during neuroinflammation suppresses encephalomyelitis and autoimmune uveitis. However, while IL-35 is structurally and functionally similar to IL
Externí odkaz:
https://doaj.org/article/c3fa3f4921364c36bd13ae8cddbd9b14
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0251962 (2021)
BackgroundWith the increasing incidence of papillary thyroid carcinoma (PTC), PTC continues to garner attention worldwide; however its pathogenesis remains to be elucidated. The purpose of this study was to explore key biomarkers and potential new th
Externí odkaz:
https://doaj.org/article/c5ca94385e264e21bee50e7c0e2179c8