Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Lijie Zhen"'
Publikováno v:
mSystems, Vol 9, Iss 9 (2024)
ABSTRACT Nontyphoidal Salmonella (NTS) is the main etiological agent of human nontyphoidal salmonellosis. The aim of this study was to analyze the epidemiological characteristics and horizontal transfer mechanisms of antimicrobial resistance (AMR) ge
Externí odkaz:
https://doaj.org/article/8e11c6eb5a0945ceab2112722439b3eb
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
This study aimed to investigate the potential mechanisms involved in the therapeutic effects of daitongxiao (DTX) on hyperuricemia (HUA). DTX was administered to two animal models of HUA via gavage feeding: HUA quail model (a uricotelic animal with u
Externí odkaz:
https://doaj.org/article/af789581c53646d395076c8f6623e263
Publikováno v:
Drug Delivery, Vol 30, Iss 1, Pp 121-132 (2023)
AbstractMethotrexate (MTX) is a first-line treatment for rheumatoid arthritis (RA), but its clinical use is greatly limited by the adverse effects and poor patient compliance caused by traditional oral administration or injection. In recent years, so
Externí odkaz:
https://doaj.org/article/1ee3f3af318148c49f728999c047de41
Publikováno v:
Engineering, Vol 19, Iss , Pp 14-21 (2022)
Externí odkaz:
https://doaj.org/article/da1b15ea3a6943bf9e45649339780a10
Autor:
Hagit Ashush, Steven D. Shapiro, Anil K. Bhunia, Aneta Gandjeva, Shyam Biswal, Gregory P. Cosgrove, Majd Mouded, Amy Richter, Thomas E. Sussan, Elena Feinstein, Rajesh K. Thimmulappa, Natalie Notkin, Mario J. Perez, Li Zhang, Emile N. Brown, Rubin M. Tuder, Toshinori Yoshida, Lijie Zhen, Anna Gelfand, Irina Petrache, Tirumalai Rangasamy, Tianzhi Mao, Igor Mett, Ugonma Chukwueke, Joel Bowman
Publikováno v:
Nature Medicine. 16:767-773
Rtp801 (also known as Redd1, and encoded by Ddit4), a stress-related protein triggered by adverse environmental conditions, inhibits mammalian target of rapamycin (mTOR) by stabilizing the TSC1-TSC2 inhibitory complex and enhances oxidative stress-de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef963fda9faf8d543c1f3dfac267bd70
https://doi.org/10.1038/nm.2157
https://doi.org/10.1038/nm.2157
Autor:
Lijie Zhen, Tirumalai Rangasamy, Rubin M. Tuder, Clarke G. Tankersley, Vikas Misra, Shyam Biswal
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 296:L888-L900
Cigarette smoking is the major risk factor for developing chronic obstructive pulmonary disease, the fourth leading cause of deaths in the United States. Despite recent advances, the molecular mechanisms involved in the initiation and progression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b54a53fd60604ad201f9f8e10001ba31
https://doi.org/10.1152/ajplung.90369.2008
https://doi.org/10.1152/ajplung.90369.2008
Mechanisms of Yajieshaba in the treatment of liver fibrosis through the Keap1-Nrf2 signaling pathway
Autor:
Yuanmei Bai, Haimei Wu, Lijie Zheng, Yuhuan Xie, Feifan Liu, Yan Wan, Qiongchao Li, Peixin Guo
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Yajieshaba (YJSB), a traditional Dai medicine formula containing botanical drugs, is commonly employed in Yunnan due to its significant therapeutic effects on liver protection. Consequently, to determine the efficacy of YJSB and the mechanism of acti
Externí odkaz:
https://doaj.org/article/448966cebfc448c794429e7583bc3a85
Autor:
Lijie Zhen, Sharon A. McGrath-Morrow, Daniel J. Hicklin, Cecilia Cho, Chung Cho, Rubin M. Tuder
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 32:420-427
Vascular endothelial growth factor (VEGF) is necessary for normal postnatal lung development and may underlie the structural lung damage that follows hyperoxic exposure. To determine the individual roles of VEGF receptors (VEGFR) 2 and 1 on postnatal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64113c225ad198c2f2208106250e36c9
https://doi.org/10.1165/rcmb.2004-0287oc
https://doi.org/10.1165/rcmb.2004-0287oc
Autor:
Tirumalai Rangasamy, Chung Y. Cho, Rajesh K. Thimmulappa, Lijie Zhen, Sorachai S. Srisuma, Thomas W. Kensler, Masayuki Yamamoto, Irina Petrache, Rubin M. Tuder, Shyam Biswal
Publikováno v:
Journal of Clinical Investigation. 114:1248-1259
Although inflammation and protease/antiprotease imbalance have been postulated to be critical in cigarette smoke–induced (CS-induced) emphysema, oxidative stress has been suspected to play an important role in chronic obstructive pulmonary diseases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86f46ee2777ca2dca05f810a28b196ad
https://doi.org/10.1172/jci200421146
https://doi.org/10.1172/jci200421146
Autor:
Sonia C. Flores, Yasunori Kasahara, Norbert F. Voelkel, Chung Y. Cho, Laima Taraseviciene-Stewart, Daniela Salvemini, Lijie Zhen, Rubin M. Tuder
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 29:88-97
We have previously demonstrated that a failure of pulmonary endothelial cell survival induced by vascular endothelial growth factor (VEGF) receptor blockade results in lung alveolar septal cell apoptosis and emphysema. Because apoptosis and oxidative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f86d0c94f2aef0409dc4586586d3e79e
https://doi.org/10.1165/rcmb.2002-0228oc
https://doi.org/10.1165/rcmb.2002-0228oc