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pro vyhledávání: '"Liisa M Prehn"'
Autor:
Liisa M Prehn, Richmond T. Prehn
Publikováno v:
Immunological Reviews. 222:341-356
Summary: The growths of many and perhaps all tumors may be stimulated rather than inhibited by a quantitatively low level of immunity. The reason tumors have antigens may be that tumors do not develop in vivo in the absence of at least a minimal immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bde5291e5cedb4e5cb1d2a680d5cbed
https://doi.org/10.1111/j.1600-065x.2008.00609.x
https://doi.org/10.1111/j.1600-065x.2008.00609.x
Autor:
Liisa M Prehn, Richmond T. Prehn
Publikováno v:
Theoretical Biology & Medical Modelling
There exists a very large literature suggesting that T cells come in a variety of species and that without the action of Tregs tumors would seldom survive inhibition by T cell effectors. We believe that much of the evidence supporting the role of Tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f4c3f0dd6b93f50483becf49d080489
https://doi.org/10.1186/1742-4682-10-42
https://doi.org/10.1186/1742-4682-10-42
Autor:
Liisa M Prehn, Richmond T. Prehn
Publikováno v:
Theoretical Biology & Medical Modelling
According to Berenblum’s two-stage hypothesis, the first stage in carcinogenesis is the production of benign premalignant lesions. Between this initiation stage and the formation of a malignant tumor there is often a long lag phase. We propose that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a447ee1bb18b6f7c670d0a09d6f145c
https://doi.org/10.1186/1742-4682-10-12
https://doi.org/10.1186/1742-4682-10-12
Autor:
Richmond T. Prehn, Liisa M Prehn
Publikováno v:
Theoretical Biology & Medical Modelling
Theoretical Biology and Medical Modelling, Vol 7, Iss 1, p 45 (2010)
Theoretical Biology and Medical Modelling, Vol 7, Iss 1, p 45 (2010)
We have previously suggested that the stimulatory effect of a weak immune reaction on tumor growth may be necessary for the growth of incipient tumors. In the present paper, we enlarge upon and extend that idea by collecting evidence in the literatur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1e585ab0066f6596bf22e175c157b5b
http://europepmc.org/articles/PMC3018371
http://europepmc.org/articles/PMC3018371
Publikováno v:
Biochemical and Biophysical Research Communications. 65:806-812
Summary In search of whether high extracellular proteolytic activity is a general tumor phenotype, we examined the levels of extracellular fibrinolytic activity due to plasminogen activation in the primary cultures of 10 lines of immunogenic and non-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a33a5f9378176c9cc617d8a09c274e50
https://doi.org/10.1016/s0006-291x(75)80216-6
https://doi.org/10.1016/s0006-291x(75)80216-6
Autor:
Liisa M. Prehn
Publikováno v:
JNCI: Journal of the National Cancer Institute. 56:833-838
A highly immunogenic mouse tumor was studied with the use of microcytotoxicity test, performed at lymphoid cell:target tumor cell ratios ranging from 1:1 to 1,000:1 at various times during tumour growth and after tumor excision. Although the tumor wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d838799ab8ad2986c20fa17e70114891
https://doi.org/10.1093/jnci/56.4.833
https://doi.org/10.1093/jnci/56.4.833
Autor:
Liisa M. Prehn
Publikováno v:
BioScience. 31:449-452
Tumor immunology as an accepted discipline is only some 20 years old, although there has been a lively interest in the possibility of conquering cancer by the body's own defense mechanism since the beginning of the century. Unfortunately, many of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41b7396273ba0f7962101f5fb32bcdb5
https://doi.org/10.2307/1308433
https://doi.org/10.2307/1308433
Autor:
Liisa M Prehn, Richmond T. Prehn
Publikováno v:
Cancer Immunology, Immunotherapy
Increasing evidence has shown that probably all malignant mouse cells, even those of spontaneous sporadic cancers, are endowed with tumor-specific antigens. Stimulation of cancer growth, rather than inhibition by the immune reaction, is seemingly the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e603772f7f7cb019fa11c0337d3dbb93
Autor:
Richmond T. Prehn, Liisa M. Prehn
Publikováno v:
Archives of surgery (Chicago, Ill. : 1960). 124(1)
• A large amount of data suggest that tumors are, to some degree, dependent for their growth on a positive level of immune reaction, a level that is unique for each tumor. Each tumor gradually adjusts its immunogenicity to the level that will, in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c58d8eba50bdb7892613cb501e302bea
https://pubmed.ncbi.nlm.nih.gov/2910236
https://pubmed.ncbi.nlm.nih.gov/2910236
Autor:
Liisa M. Prehn, Henry C. Outzen
Publikováno v:
International journal of cancer. 19(5)
Tumor implants grew better in radiated or in newborn nu/nu mice than in adult nu/nu controls when, and only when, the tumors were demonstrably immunogenic in normal mice. This result suggests primary immunity. No evidence of immunological memory was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02f9331750e1a5b70367ba8cc5cccccc
https://pubmed.ncbi.nlm.nih.gov/863547
https://pubmed.ncbi.nlm.nih.gov/863547