Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Lihou Yu"'
Autor:
Shuyang Yao, Funda Meric-Bernstam, David Hong, Filip Janku, Aung Naing, Sarina Anne Piha-Paul, Apostolia Maria Tsimberidou, Daniel Karp, Vivek Subbiah, Timothy Anthony Yap, Jordi Rodon Ahnert, Shubham Pant, Ecaterina E Ileana Dumbrava, Chetna Wathoo, Erick Campbell, Lihou Yu, Yuko Yamamura, Siqing Fu
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Cyclin E is frequently encoded by CCNE1 gene amplification in various malignancies. We reviewed the medical records of patients with solid tumors displaying CCNE1 amplification to determine the effect of this amplification for future therape
Externí odkaz:
https://doaj.org/article/a5b386ae4dfe4117b0a471663d796ae6
Autor:
Yongli Shan, Lihou Yu, Yan Li, Youdong Pan, Qiangge Zhang, Fubin Wang, Jianfeng Chen, Xueliang Zhu
Publikováno v:
PLoS Biology, Vol 7, Iss 5, p e1000116 (2009)
Adhesion and detachment are coordinated critical steps during cell migration. Conceptually, efficient migration requires both effective stabilization of membrane protrusions at the leading edge via nascent adhesions and their successful persistence d
Externí odkaz:
https://doaj.org/article/e0b32ea7395d49038a458ff06d0477ff
Autor:
Siqing Fu, Shuyang Yao, Yuan Yuan, Rebecca A. Previs, Anthony D. Elias, Richard D. Carvajal, Thomas J. George, Ying Yuan, Lihou Yu, Shannon N. Westin, Yan Xing, Ecaterina E. Dumbrava, Daniel D. Karp, Sarina A. Piha-Paul, Apostolia M. Tsimberidou, Jordi Rodon Ahnert, Naoko Takebe, Karen Lu, Khandan Keyomarsi, Funda Meric-Bernstam
Publikováno v:
Journal of Clinical Oncology. 41:1725-1734
PURPOSE Preclinical cancer models harboring CCNE1 amplification were more sensitive to adavosertib treatment, a WEE1 kinase inhibitor, than models without amplification. Thus, we conducted this phase II study to assess the antitumor activity of adavo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15a54531413a70e32f1be893f0e10364
https://doi.org/10.1200/jco.22.00830
https://doi.org/10.1200/jco.22.00830
Autor:
Siqing, Fu, Shuyang, Yao, Yuan, Yuan, Rebecca A, Previs, Anthony D, Elias, Richard D, Carvajal, Thomas J, George, Ying, Yuan, Lihou, Yu, Shannon N, Westin, Yan, Xing, Ecaterina E, Dumbrava, Daniel D, Karp, Sarina A, Piha-Paul, Apostolia M, Tsimberidou, Jordi Rodon, Ahnert, Naoko, Takebe, Karen, Lu, Khandan, Keyomarsi, Funda, Meric-Bernstam
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
Preclinical cancer models harboringPatients aged ≥ 18 years with measurable disease and refractory solid tumors harboringThirty patients were enrolled. The median follow-up duration was 9.9 months. Eight patients had partial responses (PRs), and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::987e8e74cd9ee776769cf347734c1f77
https://pubmed.ncbi.nlm.nih.gov/36469840
https://pubmed.ncbi.nlm.nih.gov/36469840
Autor:
Shuyang Yao, Funda Meric-Bernstam, David Hong, Filip Janku, Aung Naing, Sarina Anne Piha-Paul, Apostolia Maria Tsimberidou, Daniel Karp, Vivek Subbiah, Timothy Anthony Yap, Jordi Rodon Ahnert, Shubham Pant, Ecaterina E Ileana Dumbrava, Chetna Wathoo, Erick Campbell, Lihou Yu, Yuko Yamamura, Siqing Fu
Publikováno v:
Scientific reports. 12(1)
Cyclin E is frequently encoded by CCNE1 gene amplification in various malignancies. We reviewed the medical records of patients with solid tumors displaying CCNE1 amplification to determine the effect of this amplification for future therapeutic deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::044f834bbce4a3136b7444d4a47af669
https://pubmed.ncbi.nlm.nih.gov/35610322
https://pubmed.ncbi.nlm.nih.gov/35610322
Autor:
Lihou Yu, Yongli Shan, Qiangge Zhang, Fubin Wang, JianFeng Chen, Youdong Pan, Xueliang Zhu, Yan Li
Publikováno v:
PLoS Biology
PLoS Biology, Vol 7, Iss 5, p e1000116 (2009)
PLoS Biology, Vol 7, Iss 5, p e1000116 (2009)
Competition for binding to the cellular protein paxillin by the proteins Nudel and focal adhesion kinase is important for the proper regulation of cell adhesion and migration.
Adhesion and detachment are coordinated critical steps during cell mi
Adhesion and detachment are coordinated critical steps during cell mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a7ddef3e7d942e38644ca9272e0b0d8
http://europepmc.org/articles/PMC2684528
http://europepmc.org/articles/PMC2684528
Autor:
Xuefeng Lu, Zhengjun Chen, Fan Zhang, Hongyan Bao, Dan Du, Xueliang Zhu, Qin Huang, Lianghui Jia, Chenyi Zhang, Feilai Xu, Xiaohui Zhang, Xunwei Wu, Lihou Yu, Haixin Yuan, Zhe Zhang
Publikováno v:
Developmental cell. 18(1)
SummaryCell polarity proteins regulate tight junction formation and directional migration in epithelial cells. To date, the mechanism by which these polarity proteins assemble at the leading edge of migrating epithelial cells remains unclear. We repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79b9b76ab48fad49c0310fb768fe5acd
https://pubmed.ncbi.nlm.nih.gov/20152177
https://pubmed.ncbi.nlm.nih.gov/20152177
Autor:
Juan Du, Lihou Yu, Qiongping Huang, Wei Yu, Zhenye Yang, Yan Li, Yun Liang, Qiangge Zhang, Xuebiao Yao, Fubin Wang, Xueliang Zhu
The microtubule-based motor cytoplasmic dynein/dynactin is a force generator at the kinetochore. It also transports proteins away from kinetochores to spindle poles. Regulation of such diverse functions, however, is poorly understood. We have previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0468574fe9b290ae114baffd29a61b77
https://europepmc.org/articles/PMC1924840/
https://europepmc.org/articles/PMC1924840/
Publikováno v:
Cancer Research. 73:3342-3342
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death worldwide, and there are no safe and effective therapeutic agents yet to treat HCC after diagnosis. However, in HCC, genomic instability is the major remarkable hallm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::308bed8e63c96f157f9fd23b8d0a2ab0
https://doi.org/10.1158/1538-7445.am2013-3342
https://doi.org/10.1158/1538-7445.am2013-3342