Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Lihou Dong"'
Autor:
Bixia Tang, Xieqiao Yan, Xinan Sheng, Lu Si, Chuanliang Cui, Yan Kong, Lili Mao, Bin Lian, Xue Bai, Xuan Wang, Siming Li, Li Zhou, Jiayi Yu, Jie Dai, Kai Wang, Jinwei Hu, Lihou Dong, Haifeng Song, Hai Wu, Hui Feng, Sheng Yao, Zhihong Chi, Jun Guo
Publikováno v:
Journal of Hematology & Oncology, Vol 12, Iss 1, Pp 1-15 (2019)
Abstract Background JS001, a humanized IgG4 monoclonal antibody against the programmed death-1 (PD-1) receptor, blocks the interaction of PD-1 with its ligands and promotes T cell activation in preclinical studies. This phase I study is designed to e
Externí odkaz:
https://doaj.org/article/872a7a94cba2431aa8871a735b9925ba
Autor:
Guili Xu, Yi Yang, Yunhui Liu, Fang Chen, Lihou Dong, Deyou Wan, Hongjie Li, Cuima Yang, Xin Gao
Publikováno v:
Comparative Medicine. 73:145-152
Current follicle-stimulating hormone (FSH) drugs meet safety criteria but have suboptimal efficacy, poor patient compliance, and high cost. Alternative FSH-like drugs would help to meet the high market demand. Here, we evaluated X002, an FSH–Fc fus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f8c86c1f4ee608c66120de4f12769c3
https://doi.org/10.30802/aalas-cm-22-000001
https://doi.org/10.30802/aalas-cm-22-000001
Autor:
Jun Guo, Xiaoshi Zhang, Shuikui Qin, Sheng Yao, Hui Feng, Hai Wu, Haifeng Song, Lihou Dong, Weifeng Wang, Xin Song, Jing Chen, Di Wu, Xiufeng Liu, Yingbo Chen, Zhihong Chi, Bixia Tang
Sequencing Sample Listings
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31ea43b05bb60a88ff9596ca2eaa10f8
https://doi.org/10.1158/1078-0432.22477008.v1
https://doi.org/10.1158/1078-0432.22477008.v1
Autor:
Jun Guo, Xiaoshi Zhang, Shuikui Qin, Sheng Yao, Hui Feng, Hai Wu, Haifeng Song, Lihou Dong, Weifeng Wang, Xin Song, Jing Chen, Di Wu, Xiufeng Liu, Yingbo Chen, Zhihong Chi, Bixia Tang
CONSORT diagram for the Phase II study of toripalimab treating patients with locally advanced or metastatic melanoma refractory to systemic therapy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::879779fa00c660d03c27c951f13c7dee
https://doi.org/10.1158/1078-0432.22477026
https://doi.org/10.1158/1078-0432.22477026
Autor:
Jun Guo, Xiaoshi Zhang, Shuikui Qin, Sheng Yao, Hui Feng, Hai Wu, Haifeng Song, Lihou Dong, Weifeng Wang, Xin Song, Jing Chen, Di Wu, Xiufeng Liu, Yingbo Chen, Zhihong Chi, Bixia Tang
Clinical efficacy and survival evaluated by independent review committee (IRC) and investigator per RECIST v1.1 in melanoma subgroups. And Top 20% TMB value in each subtype as cut-off for efficacy analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86dc6a180557c33541e9f304ece715cb
https://doi.org/10.1158/1078-0432.22477005.v1
https://doi.org/10.1158/1078-0432.22477005.v1
Autor:
Jun Guo, Xiaoshi Zhang, Shuikui Qin, Sheng Yao, Hui Feng, Hai Wu, Haifeng Song, Lihou Dong, Weifeng Wang, Xin Song, Jing Chen, Di Wu, Xiufeng Liu, Yingbo Chen, Zhihong Chi, Bixia Tang
Purpose:In contrast to the predominant chronic UV exposure–induced cutaneous melanoma in Caucasians, acral and mucosal comprise the majority of melanomas in Asia and respond less effectively to established treatments. The clinical application of PD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a5cafde4aa501f37a9eadf103eb0d26
https://doi.org/10.1158/1078-0432.c.6529557.v1
https://doi.org/10.1158/1078-0432.c.6529557.v1
Publikováno v:
Current Medical Science. 41:618-625
Recombinant batroxobin (S3101) is a thrombin-like serine protease that binds to fibrinogen or is taken up by the reticuloendothelial system. A literature survey showed no adequate method that could determine sufficient concentrations to evaluate phar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae3bac26ae236211a2a1a312806cb01d
https://doi.org/10.1007/s11596-021-2382-6
https://doi.org/10.1007/s11596-021-2382-6
Publikováno v:
Journal of Chromatographic Science. 59:642-649
The stability and exposure of toxin-related catabolites in system circulation contributes to the evaluation of the stability, targeted delivery and off-target toxicity for antibody–drug conjugates (ADC) at different stages during drug development.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::079965dc76a305c3953548ae763c238a
https://doi.org/10.1093/chromsci/bmaa122
https://doi.org/10.1093/chromsci/bmaa122
Autor:
Bixia Tang, Zhihong Chi, Yingbo Chen, Xiufeng Liu, Di Wu, Jing Chen, Xin Song, Weifeng Wang, Lihou Dong, Haifeng Song, Hai Wu, Hui Feng, Sheng Yao, Shuikui Qin, Xiaoshi Zhang, Jun Guo
Publikováno v:
Clinical Cancer Research. 26:4250-4259
Purpose: In contrast to the predominant chronic UV exposure–induced cutaneous melanoma in Caucasians, acral and mucosal comprise the majority of melanomas in Asia and respond less effectively to established treatments. The clinical application of P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::677c552dc76028fa89a85572270b8f12
https://doi.org/10.1158/1078-0432.ccr-19-3922
https://doi.org/10.1158/1078-0432.ccr-19-3922
Autor:
Sheng Yang, Sheng Yao, Hui Feng, Hai Wu, Yuankai Shi, Haifeng Song, Shiyu Jiang, Zhishang Zhang, Yan Sun, Lihou Dong, Peng Liu, Shuxiang Zhang, Yan Qin, Ying Han, Xiaohong Han, Jiarui Yao, Jianliang Yang
Publikováno v:
European Journal of Cancer. 130:182-192
Purpose This is a first-in-human phase I study investigating the safety and efficacy of toripalimab, a humanized monoclonal antibody against the programmed cell death-1 (PD-1) receptor, in Chinese patients with advanced or recurrent malignant tumor r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0741fd3644dbba652cb6a6643c09bd74
https://doi.org/10.1016/j.ejca.2020.01.028
https://doi.org/10.1016/j.ejca.2020.01.028