Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Lihi Shaulov"'
Publikováno v:
mBio, Vol 8, Iss 1 (2017)
ABSTRACT The type III secretion system (T3SS) is a multiprotein complex that plays a central role in the virulence of many Gram-negative bacterial pathogens. To ensure that effector proteins are efficiently translocated into the host cell, bacteria m
Externí odkaz:
https://doaj.org/article/5ce7acc2076042908e85b630d44fab9b
Autor:
Manar Abboud Asleh, Mira Zaher, Jad Asleh, Julian Jadon, Lihi Shaulov, Ronit Yelin, Thomas M. Schultheiss
Publikováno v:
Developmental Cell.
Autor:
Fatimah Abd Elghani, Hazem Safory, Haya Hamza, Mor Savyon, Malik Farhoud, Michal Toren‐Hershoviz, Zagorka Vitic, Kirsten Ebanks, Vered Shani, Sleman Bisharat, Lihi Shaulov, Claude Brodski, Zhiyin Song, Rina Bandopadhyay, Simone Engelender
Publikováno v:
Aging cell. 21(12)
Parkinson's disease (PD) is characterized by degeneration of neurons, particularly dopaminergic neurons in the substantia nigra. PD brains show accumulation of α-synuclein in Lewy bodies and accumulation of dysfunctional mitochondria. However, the m
Autor:
Manar Abboud Asleh, Mira Zaher, Julian Jadon, Lihi Shaulov, Ronit Yelin, Thomas M. Schultheiss
Most mesodermal cells undergo multiple cycles of transition between an epithelial and mesenchymal state during embryonic development. While many studies have addressed the process of epithelial-to-mesenchymal transition (EMT), comparatively less is k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65bb5b276f385e92245ed369b72d5d5f
https://doi.org/10.1101/2022.03.01.482468
https://doi.org/10.1101/2022.03.01.482468
Autor:
Mor Savyon, Fatimah Abd Elghani, Ruth Rott, Kah-Leong Lim, Tsipora Cohen, Rina Bandopadhyay, Ninghan Wang, Raymonde Szargel, Simone Engelender, Vered Shani, Lihi Shaulov, Christopher A. Ross, Hazem Safory, Hui Zhang, Inna Radzishevsky, Haya Hamza
Publikováno v:
Hum Mol Genet
Mutations in LRRK2 cause autosomal dominant and sporadic Parkinson’s disease, but the mechanisms involved in LRRK2 toxicity in PD are yet to be fully understood. We found that LRRK2 translocates to the nucleus by binding to seven in absentia homolo
Autor:
Amnon Harel, Lihi Shaulov
Publikováno v:
Structure. 20:407-413
Summary Field emission scanning electron microscopy (FESEM) can provide high-resolution three-dimensional surface imaging of many biological structures, including nuclear envelopes and nuclear pore complexes (NPCs). For this purpose, it is important
Publikováno v:
Proceedings of the National Academy of Sciences
Viruses infecting bacteria (phages) are thought to greatly impact microbial population dynamics as well as the genome diversity and evolution of their hosts. Here we report on the discovery of a novel lineage of tailed dsDNA phages belonging to the f
Autor:
John M. Shelton, Joachim Seemann, Daniel R. Nussenzveig, Bandarigoda N. Somatilaka, Liang Zhang, Sharon K. Kuss, Beatriz M. A. Fontoura, Ramanavelan Sakthivel, Amnon Harel, Jue Yang, Thais Garcias Moreira, Lihi Shaulov, Ana Maria Caetano Faria, Jessica S. Williams
Publikováno v:
Scientific Reports
The Sec13 protein functions in various intracellular compartments including the nuclear pore complex, COPII-coated vesicles and inside the nucleus as a transcription regulator. Here we developed a mouse model that expresses low levels of Sec13 (Sec13
Publikováno v:
Mechanisms of Development. 145:S155-S156
Publikováno v:
Nucleic Acids Research
The prime mechanism by which p53 acts as a tumor suppressor is as a transcription factor regulating the expression of diverse downstream genes. The DNA-binding domain of p53 (p53DBD) interacts with defined DNA sites and is the main target for mutatio