Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Lihao Ge"'
Autor:
Xiaomei Zhang, Lihao Ge, Guanghui Jin, Yasong Liu, Qingfen Yu, Weizhao Chen, Liang Chen, Tao Dong, Kiyoharu J. Miyagishima, Juan Shen, Jinghong Yang, Guo Lv, Yan Xu, Qing Yang, Linsen Ye, Shuhong Yi, Hua Li, Qi Zhang, Guihua Chen, Wei Liu, Yang Yang, Wei Li, Jingxing Ou
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Cold-induced injuries severely limit opportunities and outcomes of hypothermic therapies and organ preservation, calling for better understanding of cold adaptation. Here, by surveying cold-altered chromatin accessibility and integrated CUT&
Externí odkaz:
https://doaj.org/article/d998e4517370496592792e959647a452
Autor:
Gianvito Arpino, Agila Somasundaram, Wonchul Shin, Lihao Ge, Seth Villareal, Chung Yu Chan, Uri Ashery, Oleg Shupliakov, Justin W. Taraska, Ling-Gang Wu
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103809- (2022)
Summary: Clathrin-mediated endocytosis, the most prominent endocytic mode, is thought to be generated primarily from relatively flat patches of the plasma membrane. By employing conventional and platinum replica electron microscopy and super-resoluti
Externí odkaz:
https://doaj.org/article/b97afdad4fb9476ba4767ca24af811ab
Autor:
Wonchul Shin, Gianvito Arpino, Sathish Thiyagarajan, Rui Su, Lihao Ge, Zachary McDargh, Xiaoli Guo, Lisi Wei, Oleg Shupliakov, Albert Jin, Ben O’Shaughnessy, Ling-Gang Wu
Publikováno v:
Cell Reports, Vol 30, Iss 2, Pp 421-431.e7 (2020)
Summary: For decades, two fusion modes were thought to control hormone and transmitter release essential to life; one facilitates release via fusion pore dilation and flattening (full collapse), and the other limits release by closing a narrow fusion
Externí odkaz:
https://doaj.org/article/2e0c03cc3d67471682425f47514a1185
Autor:
Lihao Ge, Wonchul Shin, Gianvito Arpino, Lisi Wei, Chung Yu Chan, Christopher K. E. Bleck, Weidong Zhao, Ling-Gang Wu
Publikováno v:
Science advances. 8(24)
Vesicle fusion at preestablished plasma membrane release sites releases transmitters and hormones to mediate fundamental functions like neuronal network activities and fight-or-flight responses. This half-a-century-old concept—fusion at well-establ
Publikováno v:
NeuroReport. 32:112-120
Our previous study demonstrated that adenovirus-delivered GFP nuclear heme oxygenase-1 (nuclear HO-1, NHO-1) fragments lacking 23 amino acids at the C-terminus (Ad-GFP-HO-1C[INCREMENT]23) showed the potential therapeutic effects mediated by its impro
Vesicle fusion is assumed to occur at flat membrane of excitable cells. In live neuroendocrine cells, we visualized vesicle fusion at Ω-shape membrane generated by preceding fusion, termed sequential compound fusion, which may be followed by fusion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::692c426412b7fe9369d1bb446e48220d
https://doi.org/10.1101/2021.06.21.449230
https://doi.org/10.1101/2021.06.21.449230
Autor:
Tianming Li, Lihao Ge, Saurabh Pandey, Wei Lu, Ya-Xian Wang, Xiumin Chen, Kunwei Wu, Kenneth A. Pelkey, Chris J. McBain, Ling-Gang Wu, David Castellano, Jun Li, Ronald S. Petralia, Joseph W. Lynch, Wenyan Han, Chengyu Liu
Publikováno v:
Science. 366:246-250
Fine control of brain GABA A receptors GABA A (γ-aminobutyric acid type A) receptors are ligand-gated anion channels that mediate fast inhibitory transmission in the mammalian brain. Han et al. investigated if a protein called SHISA7 was involved in
Autor:
Wonchul Shin, Lihao Ge, Christopher K. E. Bleck, Ling-Gang Wu, Oleg Shupliakov, Chung Yu Chan, Gianvito Arpino, Edaeni Hamid, Lisi Wei, Xiaoli Guo
Publikováno v:
Neuron. 109(19)
Transformation of flat membrane into round vesicles is generally thought to underlie endocytosis and produce speed-, amount-, and vesicle-size-specific endocytic modes. Visualizing depolarization-induced exocytic and endocytic membrane transformation
Publikováno v:
Biochemical and biophysical research communications. 525(3)
The blood-spinal cord barrier (BSCB) is an effective, tightly-connected tissue that reduces secondary spinal cord injury (SCI) by decreasing blood cell infiltration, inflammation, and neuronal cell death during primary SCI. However, the methods and m
Autor:
Deshui Yu, Yunlong Bi, Yang Cao, Zhanpeng Guo, Rui Sun, Lihao Ge, Yajiang Yuan, Peng Teng, Yuyan Wang, Yansong Wang, Gang Li
Publikováno v:
Biotechnology Letters. 40:1477-1486
MicroRNA-429(miR-429) plays an important role in mesenchymal stem cells. Hypoxia-inducible factor 1α (HIF-1α) is a nuclear transcription factor that regulates the proliferation, apoptosis and tolerance to hypoxia of mesenchymal stem cells. HIF-1α