Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Lihai, Yu"'
Autor:
Sara Ghiassian, Lihai Yu, Pierangelo Gobbo, Ali Nazemi, Tommaso Romagnoli, Wilson Luo, Leonard G. Luyt, Mark S. Workentin
Publikováno v:
ACS Omega, Vol 4, Iss 21, Pp 19106-19115 (2019)
Externí odkaz:
https://doaj.org/article/d58703d7a9cc45d79d0f3568bd3f56d6
Autor:
Ahmed Abbas MSc, Lihai Yu PhD, Tyler Lalonde BSc, Derek Wu BSc, Jonathan D. Thiessen PhD, Leonard G. Luyt PhD, Savita Dhanvantari PhD
Publikováno v:
Molecular Imaging, Vol 17 (2018)
One-third of patients with heart disease develop heart failure, which is diagnosed through imaging and detection of circulating biomarkers. Imaging strategies reveal morphologic and functional changes but fall short of detecting molecular abnormaliti
Externí odkaz:
https://doaj.org/article/347f82c48655400bafc3a69fbf90d32e
Publikováno v:
Organic & Biomolecular Chemistry. 19:8812-8820
The growth hormone secretagogue receptor 1a (GHSR) is differentially expressed in various disease states compared to healthy tissues and thus is a target for molecular imaging. The endogenous ligand for the GHSR is ghrelin, a 28 amino acid peptide wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eda4fa18abcc843773abfe79c3fa95c9
https://doi.org/10.1039/d1ob01023a
https://doi.org/10.1039/d1ob01023a
Autor:
Babak Behnam Azad, Vanessa Rota, Lihai Yu, Rebecca Mcgirr, André H. St. Amant, Ting-Yim Lee, Savita Dhanvantari, Leonard G. Luyt PhD
Publikováno v:
Molecular Imaging, Vol 14 (2015)
A fluorescein-GLP-1 (7-37) analog was generated to determine GLP-1R distribution in various cell types of the pancreas in both strains of mice and receptor-specific uptake was confirmed by blocking with exendin-4. Biodistribution studies were carried
Externí odkaz:
https://doaj.org/article/5f3b5e72033541fca3b13a2fb36b1292
Autor:
Leonard G. Luyt, Sara Ghiassian, Wilson Luo, Pierangelo Gobbo, Ali Nazemi, Mark S. Workentin, Lihai Yu, Tommaso Romagnoli
Publikováno v:
ACS Omega
ACS Omega, Vol 4, Iss 21, Pp 19106-19115 (2019)
ACS Omega, Vol 4, Iss 21, Pp 19106-19115 (2019)
A novel bioorthogonal gold nanoparticle (AuNP) template displaying interfacial nitrone functional groups for bioorthogonal interfacial strain-promoted alkyne-nitrone cycloaddition reactions has been synthesized. These nitrone-AuNPs were characterized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec186ee6e140cd1553cddefa317ee9d7
https://doi.org/10.1021/acsomega.9b02322
https://doi.org/10.1021/acsomega.9b02322
Autor:
Devika P Bagchi, Lihai Yu, Joel S Perlmutter, Jinbin Xu, Robert H Mach, Zhude Tu, Paul T Kotzbauer
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55031 (2013)
Accumulation of α-synuclein (α-syn) fibrils in Lewy bodies and Lewy neurites is the pathological hallmark of Parkinson disease (PD). Ligands that bind α-syn fibrils could be utilized as imaging agents to improve the diagnosis of PD and to monitor
Externí odkaz:
https://doaj.org/article/3dc49713006942b79b9bdd0d8d29ae74
Autor:
Lise Desjardin, Lihai Yu, Laura Morrison, Justin W. Hicks, Jennifer Hadway, Ting-Yim Lee, Fiona Li
Publikováno v:
EJNMMI Research
BackgroundIn molecular imaging with dynamic PET, the binding and dissociation of a targeted tracer is characterized by kinetics modeling which requires the arterial concentration of the tracer to be measured accurately. Once in the body the radiolabe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2162e7932d8dcbfeb0d8ed67c08dceb5
http://europepmc.org/articles/PMC7683627
http://europepmc.org/articles/PMC7683627
Autor:
Fiona Li, Justin W Hicks, Lihai Yu, Lise Desjardin, Laura Morrison, Jennifer Hadway, Ting-Yim Lee
Background In molecular imaging with dynamic PET, the binding and dissociation of a targeted tracer is characterized by kinetics modeling which requires the arterial concentration of the tracer to be measured accurately. Once in the body the radiolab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97f6e12632d5613f64446e748262038a
https://doi.org/10.21203/rs.3.rs-35592/v3
https://doi.org/10.21203/rs.3.rs-35592/v3
Publikováno v:
Organic & Biomolecular Chemistry. 17:598-608
The C-X-C chemokine receptor 4 (CXCR4) has been shown to be overexpressed in at least 23 types of cancer, including prostate cancer which has been shown to have a significant distinction of expression rates between cancerous compared to healthy or be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58cd72ebab3dfe1be5ced6fec6e2a918
https://doi.org/10.1039/c8ob01947a
https://doi.org/10.1039/c8ob01947a
Autor:
Sara Ghiassian, Lihai Yu, Pierangelo Gobbo, Ali nazemi, Tommaso Romagnoli, Wilson Luo, Leonard G. Luyt, Mark Workentin
A bioorthogonal gold nanoparticle template displaying interfacial nitrone functional groups for bioorthogonal interfacial strain-promoted alkyne-nitrone cycloaddition (I-SPANC) reactions has been synthesized. The Nitrone-AuNPs were characterized in d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f0714b9372394a765c4e29786ab21ae
https://doi.org/10.26434/chemrxiv.9036944
https://doi.org/10.26434/chemrxiv.9036944