Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Lih-Wen Deng"'
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Mesenchymal stem cells (MSCs) have garnered significant interest for their tumor-tropic property, making them potential therapeutic delivery vehicles for cancer treatment. We have previously shown the significant anti-tumour activ
Externí odkaz:
https://doaj.org/article/1c3ef94756d04a3982f8cabf16117a44
Autor:
Xiaoming Zhang, Bo-Wen Zhang, Lue Xiang, Hui Wu, SUPIT Alva Sahiri Alexander, Peipei Zhou, Melvin Zi-Yu Dai, Xiaoyun Wang, Wenjun Xiong, Yan Zhang, Zi-Bing Jin, Lih-Wen Deng
Publikováno v:
iScience, Vol 25, Iss 4, Pp 104058- (2022)
Summary: Histone methylation, particularly at the H3K4 position, is thought to contribute to the specification of photoreceptor cell fate; however, the mechanisms linking histone methylation with transcription factor transactivation and photoreceptor
Externí odkaz:
https://doaj.org/article/90435ad2a4ef4ea1aba3fdc87ab862ee
Autor:
Dawn Sijin Nin, Lih-Wen Deng
Publikováno v:
Cells, Vol 12, Iss 6, p 926 (2023)
Tumour-specific antigens have been an area of interest in cancer therapy since their discovery in the middle of the 20th century. In the era of immune-based cancer therapeutics, redirecting our immune cells to target these tumour-specific antigens ha
Externí odkaz:
https://doaj.org/article/09f9dce492374120a7282a47d87455cc
Rap1 regulates hematopoietic stem cell survival and affects oncogenesis and response to chemotherapy
Autor:
Ekta Khattar, Kyaw Ze Ya Maung, Chen Li Chew, Arkasubhra Ghosh, Michelle Meng Huang Mok, Pei Lee, Jun Zhang, Wei Hong Jeff Chor, Gökhan Cildir, Chelsia Qiuxia Wang, Nur Khairiah Mohd-Ismail, Desmond Wai Loon Chin, Soo Chin Lee, Henry Yang, Yong-Jae Shin, Do-Hyun Nam, Liming Chen, Alan Prem Kumar, Lih Wen Deng, Masahito Ikawa, Jayantha Gunaratne, Motomi Osato, Vinay Tergaonkar
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Rap1 is a telomeric protein that is highly expressed in cancers. Here, the authors show that Rap1 interacts with several DNA repair proteins independent of its telomere function to enhance DNA repair and that its deficiency leads to accelerated tumor
Externí odkaz:
https://doaj.org/article/3e889e3b0c2349c59ada25c89786da9e
Publikováno v:
Journal of Functional Foods, Vol 35, Iss , Pp 197-204 (2017)
Hydrogen sulphide (H2S) is a gasotransmitter with multiple cellular signaling functions, and substantial number of H2S donors has been reported for research and therapeutic applications. However, most of the H2S donors are synthetic compounds. Natura
Externí odkaz:
https://doaj.org/article/600750fdc4b944c7ae06c01a656dddab
We previously identified a novel MLL5 isoform, MLL5β, which was essential for E6 and E7 transcriptional activation in HPV16/18-associated cervical cancers. In this report, we investigated the potential of RNAi-mediated silencing of MLL5β through th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1144974dd3f617daf3558a3fbc44da93
https://doi.org/10.1158/1535-7163.c.6537139
https://doi.org/10.1158/1535-7163.c.6537139
Supplementary Table 1: Sequences of siRNAs used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bcb406ba45496b2548b4a96d14764d8
https://doi.org/10.1158/1535-7163.22502635
https://doi.org/10.1158/1535-7163.22502635
Supplementary Figure S2: Pixel density analysis of E6 and E7 protein expression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::744ee0cdfc126c8719e51ce3efd5a4e1
https://doi.org/10.1158/1535-7163.22502638
https://doi.org/10.1158/1535-7163.22502638
Supplementary Table 2: Sequences of primers used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36a2296370afc2ca2ee30de97136aa89
https://doi.org/10.1158/1535-7163.22502632
https://doi.org/10.1158/1535-7163.22502632