Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Liguori MJ"'
Autor:
Weaver, RJ, Betts, C, Blomme, EAG, Gerets, HHJ, Gjervig Jensen, K, Hewitt, PG, Juhila, S, Labbe, G, Liguori, MJ, Mesens, N, Ogese, MO, Persson, M, Snoeys, J, Stevens, JL, Walker, T, Park, BK
Publikováno v:
Expert opinion on drug metabolism & toxicology
Introduction The liver is an important target for drug-induced toxicities. Early detection of hepatotoxic drugs requires use of well-characterized test systems, yet current knowledge, gaps and limitations of tests employed remains an important issue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::37f47d10edd3d3971facceffb220ca8f
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Akademický článek
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Akademický článek
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Autor:
Russomanno G; Department of Pharmacology & Therapeutics, Institute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool, L69 3GE, UK., Sison-Young R; Department of Pharmacology & Therapeutics, Institute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool, L69 3GE, UK., Livoti LA; Department of Pharmacology & Therapeutics, Institute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool, L69 3GE, UK., Coghlan H; Department of Pharmacology & Therapeutics, Institute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool, L69 3GE, UK., Jenkins RE; Department of Pharmacology & Therapeutics, Institute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool, L69 3GE, UK.; CDSS Bioanalytical Facility, Institute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool, L69 3GE, UK., Kunnen SJ; Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research (LACDR), Leiden University, Leiden, 2311 EZ, The Netherlands., Fisher CP; Simcyp Division, Certara UK, Sheffield, S1 2BJ, UK., Reddyhoff D; Simcyp Division, Certara UK, Sheffield, S1 2BJ, UK., Gardner I; Simcyp Division, Certara UK, Sheffield, S1 2BJ, UK., Rehman AH; Department of Pharmacology & Therapeutics, Institute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool, L69 3GE, UK.; Department of Hepatobiliary Surgery, Aintree University Hospital, Liverpool University Hospitals NHS Foundation Trust, Liverpool, L9 7AL, UK., Fenwick SW; Department of Hepatobiliary Surgery, Aintree University Hospital, Liverpool University Hospitals NHS Foundation Trust, Liverpool, L9 7AL, UK., Jones AR; Department of Biochemistry & Systems Biology, Institute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool, L69 7ZB, UK., Vermeil De Conchard G; Translational Medicine, Non Clinical Safety, Biologie Servier, Gidy, 45520, France., Simonin G; Translational Medicine, Non Clinical Safety, Biologie Servier, Gidy, 45520, France., Bertheux H; Translational Medicine, Non Clinical Safety, Biologie Servier, Gidy, 45520, France., Weaver RJ; Institut de R&D Servier Paris-Saclay, Gif sur Yvette, 91190, France., Johnson RL; Eli Lilly and Company, Indianapolis, Indiana 46225, USA., Liguori MJ; AbbVie Inc., Pre-Clinical Safety, Chicago, Illinois 60064, USA., Clausznitzer D; AbbVie Deutschland GmbH & Co. KG, DMPK-BA, Ludwigshafen, 67061, Germany., Stevens JL; Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research (LACDR), Leiden University, Leiden, 2311 EZ, The Netherlands., Goldring CE; Department of Pharmacology & Therapeutics, Institute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool, L69 3GE, UK., Copple IM; Department of Pharmacology & Therapeutics, Institute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool, L69 3GE, UK.
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2023 Oct 30; Vol. 196 (1), pp. 112-125.
Autor:
Green JR; Departments of Preclinical Safety, AbbVie, 1 North Waukegan Road, North Chicago, IL 60064, United States. Electronic address: jonathon.green@abbvie.com., Mahalingaiah PKS; Departments of Preclinical Safety, AbbVie, 1 North Waukegan Road, North Chicago, IL 60064, United States., Gopalakrishnan SM; Drug Discovery Science and Technology, AbbVie, 1 North Waukegan Road, North Chicago, IL 60064, United States., Liguori MJ; Departments of Preclinical Safety, AbbVie, 1 North Waukegan Road, North Chicago, IL 60064, United States., Mittelstadt SW; Departments of Preclinical Safety, AbbVie, 1 North Waukegan Road, North Chicago, IL 60064, United States., Blomme EAG; Departments of Preclinical Safety, AbbVie, 1 North Waukegan Road, North Chicago, IL 60064, United States., Van Vleet TR; Departments of Preclinical Safety, AbbVie, 1 North Waukegan Road, North Chicago, IL 60064, United States.
Publikováno v:
Journal of pharmacological and toxicological methods [J Pharmacol Toxicol Methods] 2023 Sep-Oct; Vol. 123, pp. 107468. Date of Electronic Publication: 2023 Aug 06.
Autor:
Wetter JM; AbbVie, Inc., North Chicago, Illinois (J.M.W., R.C., C.J.K., M.J.L., J.C.K.); and AbbVie Bioresearch Center, Worcester, Massachusetts (C.G., S.M.) jill.wetter@abbvie.com., Ciurlionis R; AbbVie, Inc., North Chicago, Illinois (J.M.W., R.C., C.J.K., M.J.L., J.C.K.); and AbbVie Bioresearch Center, Worcester, Massachusetts (C.G., S.M.)., Krause CJ; AbbVie, Inc., North Chicago, Illinois (J.M.W., R.C., C.J.K., M.J.L., J.C.K.); and AbbVie Bioresearch Center, Worcester, Massachusetts (C.G., S.M.)., Liguori MJ; AbbVie, Inc., North Chicago, Illinois (J.M.W., R.C., C.J.K., M.J.L., J.C.K.); and AbbVie Bioresearch Center, Worcester, Massachusetts (C.G., S.M.)., Goess C; AbbVie, Inc., North Chicago, Illinois (J.M.W., R.C., C.J.K., M.J.L., J.C.K.); and AbbVie Bioresearch Center, Worcester, Massachusetts (C.G., S.M.)., Mathieu S; AbbVie, Inc., North Chicago, Illinois (J.M.W., R.C., C.J.K., M.J.L., J.C.K.); and AbbVie Bioresearch Center, Worcester, Massachusetts (C.G., S.M.)., Kalvass JC; AbbVie, Inc., North Chicago, Illinois (J.M.W., R.C., C.J.K., M.J.L., J.C.K.); and AbbVie Bioresearch Center, Worcester, Massachusetts (C.G., S.M.).
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2023 Aug; Vol. 51 (8), pp. 1005-1015. Date of Electronic Publication: 2023 May 04.
Autor:
Krause C; R & D Data Solutions, AbbVie, North Chicago, IL, United States., Suwada K; Development Biological Sciences, AbbVie, North Chicago, IL, United States., Blomme EAG; Development Biological Sciences, AbbVie, North Chicago, IL, United States., Kowalkowski K; Development Biological Sciences, AbbVie, North Chicago, IL, United States., Liguori MJ; Development Biological Sciences, AbbVie, North Chicago, IL, United States., Mahalingaiah PK; Development Biological Sciences, AbbVie, North Chicago, IL, United States., Mittelstadt S; Development Biological Sciences, AbbVie, North Chicago, IL, United States., Peterson R; Development Biological Sciences, AbbVie, North Chicago, IL, United States., Rendino L; Development Biological Sciences, AbbVie, North Chicago, IL, United States., Vo A; Development Biological Sciences, AbbVie, North Chicago, IL, United States., Van Vleet TR; Development Biological Sciences, AbbVie, North Chicago, IL, United States.
Publikováno v:
Frontiers in genetics [Front Genet] 2023 Jan 17; Vol. 13, pp. 1078050. Date of Electronic Publication: 2023 Jan 17 (Print Publication: 2022).
Autor:
Sharapova T; Investigative Toxicology and Pathology, AbbVie Inc., North Chicago, IL, United States. Electronic address: Tatsiana.sharapova@abbvie.com., Talaty N; Discovery Platform Technologies, AbbVie Inc., North Chicago, IL, United States., Buck WR; Investigative Toxicology and Pathology, AbbVie Inc., North Chicago, IL, United States., Fossey S; Investigative Toxicology and Pathology, AbbVie Inc., North Chicago, IL, United States., Liguori MJ; Investigative Toxicology and Pathology, AbbVie Inc., North Chicago, IL, United States., Van Vleet TR; Investigative Toxicology and Pathology, AbbVie Inc., North Chicago, IL, United States.
Publikováno v:
Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2021 Mar 15; Vol. 415, pp. 115439. Date of Electronic Publication: 2021 Feb 05.