Functional characterization of human phosphomannomutases by 31P-NMR

Autor: Andreotti G. 1, Liguori L. 1, 3, Monticelli M. 1, 2, Viscido G. 2, Cimmaruta C. 2, Citro V. 2, Cubellis M.V. 2

Publikováno v: Scientific CDG Symposium 2017, Leuven Institute for Irelan in Europe, 13-14/07/2017
info:cnr-pdr/source/autori:Andreotti G. 1, Liguori L. 1,3, Monticelli M. 1,2, Viscido G. 2, Cimmaruta C. 2, Citro V. 2, Cubellis M.V. 2/congresso_nome:Scientific CDG Symposium 2017/congresso_luogo:Leuven Institute for Irelan in Europe/congresso_data:13-14%2F07%2F2017/anno:2017/pagina_da:/pagina_a:/intervallo_pagine

PMM2-CDG is caused by mutations in the gene PMM2 encoding phosphomannomutase2. Yet a paralogous enzyme exists in humans. PMM1 has an additional phosphatase activity and is able to hydrolyze glucose and mannose 1,6 bisphosphate. This latter activity i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::258d5d3041043dff4295c8e574dca627
https://publications.cnr.it/doc/379478