Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Liguo Niu"'
Autor:
James M Termini, Sachin Gupta, Francesca N Raffa, Elizabeth Guirado, Margaret A Fischl, Liguo Niu, Saravana Kanagavelu, Geoffrey W Stone
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184915 (2017)
Dendritic cells (DC) are a promising cell type for cancer vaccines due to their high immunostimulatory capacity. However, improper maturation of DC prior to treatment may account for the limited efficacy of DC vaccine clinical trials. Latent Membrane
Externí odkaz:
https://doaj.org/article/448aad0fe5154a0d839799023da9a83b
Autor:
Saravana Kanagavelu, Liguo Niu, James M. Termini, Richard S. Kornbluth, Helena Schmidtmayerova, Geoffrey W. Stone, Sachin Gupta, Victoria Snarsky
Publikováno v:
Journal of Leukocyte Biology. 90:389-398
HIV-1 does not significantly activate cellular immunity, which has made it difficult to use attenuated forms of HIV-1 as a vaccine. In contrast, EBV induces robust T cell responses in most infected individuals, perhaps as this virus contains LMP1, a
Autor:
Lieping Chen, Liguo Niu, Trent Spencer, Benyue Zhang, Simona Strahotin, David R. Archer, Becker Hewes, Robert S. Mittler, Byoung S. Kwon, Anthony T. Vella, Dirck L. Dillehay, Yuanyuan Zhang
Publikováno v:
The Journal of Immunology. 178:4194-4213
CD137-mediated signals costimulate T cells and protect them from activation-induced apoptosis; they induce curative antitumor immunity and enhance antiviral immune responses in mice. In contrast, anti-CD137 agonistic mAbs can suppress T-dependent hum
Autor:
Daniela, Max, Caspar D, Kühnöl, Stefan, Burdach, Liguo, Niu, Martin S, Staege, Jürgen L, Föll
Publikováno v:
Anticancer research. 34(11)
Interleukin-2 (IL2) transgenic Ewing sarcoma cells reduce tumor growth in vivo and in vitro. In the present study we analyzed the expression of immune suppressive indoleamine-2,3-dioxygenase (IDO) in this model.Expression of IDO was analyzed by polym
Autor:
L. Becker Hewes, Abhijit Bapat, Liguo Niu, Juergen Foell, Simona Strahotin, Robert S. Mittler, Megan McCausland
Publikováno v:
Immunologic Research. 29:197-208
CD137 (4-1BB), is an inducible T-cell costimulatory receptor and a member of the tumor necrosis factor receptor (TNFR) superfamily. It is expressed on activated T cells and activated natural killer (NK) cells, but is constitutively expressed on a pop
Autor:
Francesca N. Raffa, Sachin Gupta, Liguo Niu, Geoffrey W. Stone, Saravana Kanagavelu, Elizabeth Guirado, James M. Termini, Margaret A. Fischl
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184915 (2017)
PLoS ONE
PLoS ONE
Dendritic cells (DC) are a promising cell type for cancer vaccines due to their high immunostimulatory capacity. However, improper maturation of DC prior to treatment may account for the limited efficacy of DC vaccine clinical trials. Latent Membrane
Autor:
Liguo Niu, Sachin Gupta, Richard S. Kornbluth, Geoffrey W. Stone, James M. Termini, Andrew R. Rahmberg, David T. Evans, Saravana Kanagavelu
Publikováno v:
Retrovirology
Retrovirology, Vol 8, Iss 1, p 39 (2011)
Retrovirology, Vol 8, Iss 1, p 39 (2011)
Background Molecular adjuvants are a promising method to enhance virus-specific immune responses and protect against HIV-1 infection. Immune activation by ligands for receptors such as CD40 can induce dendritic cell activation and maturation. Here we
Autor:
James I. Mullins, James M. Termini, George N. Pavlakis, Geoffrey W. Stone, Sachin Gupta, Morgane Rolland, Viraj Kulkarni, Margaret A. Fischl, Liguo Niu, Saravana Kanagavelu, Barbara K. Felber
Publikováno v:
Vaccine. 29(11)
Dendritic cell (DC) therapy is a promising technology for the treatment of HIV infected individuals. HIV-1 Gag- and Nef RNA-loaded DC have previously been shown to induce immune responses ex vivo following coculture with autologous lymphocytes. Howev
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 184(9)
Agonistic anti-CD137 mAbs either positively or negatively regulate T cell function. When administered at the beginning of lymphocytic choriomeningitis virus Armstrong infection anti-CD137 induced immunosuppression and T cell deletion, and in the case
Publikováno v:
CD137 Pathway: Immunology and Diseases ISBN: 9780387313221
CD137 (4-1BB), a member of the tumor necrosis factor receptor (TNFR) superfamily is an activation-inducible type I transmembrane protein receptor expressed on activated T cells, Natural Killer cells (NK), macrophages (Mφ), and dendritic cells (DC).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08d85c1918f2759d5c0c50384137c522
https://doi.org/10.1007/0-387-32829-7_5
https://doi.org/10.1007/0-387-32829-7_5