Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Lige, Tonggu"'
Autor:
Lige Tonggu, Goragot Wisedchaisri, Tamer M. Gamal El-Din, Michael J. Lenaeus, Matthew M. Logan, Tatsuya Toma, Justin Du Bois, Ning Zheng, William A. Catterall
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract The poison dart toxin batrachotoxin is exceptional for its high potency and toxicity, and for its multifaceted modification of the function of voltage-gated sodium channels. By using cryogenic electron microscopy, we identify two homologous,
Externí odkaz:
https://doaj.org/article/0cd0beb8ab5c4f2796f93d647ea54c87
Autor:
Daohua Jiang, Lige Tonggu, Tamer M. Gamal El-Din, Richard Banh, Régis Pomès, Ning Zheng, William A. Catterall
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The α-toxin LqhIII from the deathstalker scorpion inhibits fast inactivation of cardiac NaV1.5 channels. Here authors reveal the cryo-EM structure of LqhIII bound to NaV1.5 which shows that LqhIII traps the gating charges of the S4 segment in a uniq
Externí odkaz:
https://doaj.org/article/551ce5bc8824402bb013e154205ef0bc
Autor:
Min‐juan Shen, Kai Jiao, Chen‐yu Wang, Hermann Ehrlich, Mei‐chen Wan, Dong‐xiao Hao, Jing Li, Qian‐qian Wan, Lige Tonggu, Jian‐fei Yan, Kai‐yan Wang, Yu‐xuan Ma, Ji‐hua Chen, Franklin R. Tay, Li‐na Niu
Publikováno v:
Advanced Science, Vol 9, Iss 11, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/2bf43cd239464c91a18c0074be38cc7f
Autor:
Lige Tonggu, Liguo Wang
Publikováno v:
Membranes, Vol 12, Iss 8, p 758 (2022)
Voltage-gated and ligand-modulated ion channels play critical roles in excitable cells. To understand the interplay among voltage sensing, ligand binding, and channel opening, the structures of ion channels in various functional states and in lipid m
Externí odkaz:
https://doaj.org/article/8d7e5ea9e1aa40d2889e23181ae35f5e
Publikováno v:
Nature Cardiovascular Research.
Autor:
Jia-xin Hao, Franklin R. Tay, Yi-fei Zhu, Dong-xiao Hao, Xiao-xiao Han, Chen yu Wang, Kai Jiao, Jihua Chen, Li Na Niu, Min-juan Shen, Lige Tonggu
Publikováno v:
Advanced materials (Deerfield Beach, Fla.). 34(9)
The visionary idea that RNA adopts non-biological roles in today's nanomaterial world has been nothing short of phenomenal. These RNA molecules have ample chemical functionality and self-assemble to form distinct nanostructures in response to externa
Autor:
Régis Pomès, Daohua Jiang, Tamer M. Gamal El-Din, Richard Banh, Lige Tonggu, Ning Zheng, William A. Catterall
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications
Voltage-gated sodium (NaV) channels initiate action potentials in excitable cells, and their function is altered by potent gating-modifier toxins. The α-toxin LqhIII from the deathstalker scorpion inhibits fast inactivation of cardiac NaV1.5 channel
Autor:
Régis Pomès, Richard Banh, Ning Zheng, Daohua Jiang, T.M. Gamal El-Din, Lige Tonggu, William A. Catterall
Voltage-gated sodium (NaV) channels initiate action potentials in excitable cells, and their function is altered by potent gating-modifier toxins. The α-toxin LqhIII from the deathstalker scorpion inhibits fast inactivation of cardiac NaV1.5 channel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46fb2645cc94482f13d9d2e905ad75ac
https://doi.org/10.1101/2020.12.28.424592
https://doi.org/10.1101/2020.12.28.424592
Autor:
Min‐juan Shen, Chen‐yu Wang, Dong‐xiao Hao, Jia‐xin Hao, Yi‐fei Zhu, Xiao‐xiao Han, Lige Tonggu, Ji‐hua Chen, Kai Jiao, Franklin R. Tay, Li‐na Niu
Publikováno v:
Advanced Materials. 34:2270068
Autor:
Daohua Jiang, Richard L. Banh, Tamer M. Gamal El-Din, Lige Tonggu, Michael J. Lenaeus, Regis Pomes, Ning Zheng, William A. Catterall
Publikováno v:
Biophysical Journal. 121:24a