Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Lifted, Sichali"'
Contribution of remote M.tuberculosis infection to tuberculosis disease: A 30-year population study.
Autor:
Judith R Glynn, Palwasha Khan, Themba Mzembe, Lifted Sichali, Paul E M Fine, Amelia C Crampin, Rein M G J Houben
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0278136 (2023)
BackgroundThe importance of remote infection with M.tuberculosis as a cause of tuberculosis disease (TB) is unclear, with limited evidence of impact on TB rates beyond 10 years. Our objective was to assess rates of tuberculosis over 30 years by M.tub
Externí odkaz:
https://doaj.org/article/955718cf7bf84400b673e2a73986366b
Autor:
Thomas C. Morris, Clive J. Hoggart, Novel N. Chegou, Martin Kidd, Tolu Oni, Rene Goliath, Katalin A. Wilkinson, Hazel M. Dockrell, Lifted Sichali, Louis Banda, Amelia C. Crampin, Neil French, Gerhard Walzl, Michael Levin, Robert J. Wilkinson, Melissa S. Hamilton
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Accurate and affordable point-of-care diagnostics for tuberculosis (TB) are needed. Host serum protein signatures have been derived for use in primary care settings, however validation of these in secondary care settings is lacking. We evaluated seru
Externí odkaz:
https://doaj.org/article/51c489d763544543b30c92592ca05a5a
Autor:
Lifted Sichali, Jorg M. Ponnighaus, Louis Banda, Judith R. Glynn, Estelle McLean, Amelia C. Crampin, Themba Mzembe, Paul E. M. Fine, D. K. Warndorff, Chifundo Kanjala, Katherine Fielding
Publikováno v:
The Lancet. Global Health
Summary Background A large, double-blind, randomised, placebo-controlled trial of repeat BCG found 49% efficacy against leprosy but no protection against tuberculosis after 6–9 years’ follow-up in 1995. We report here additional follow-up, which
Autor:
Judith R Glynn, José Afonso Guerra-Assunção, Rein M G J Houben, Lifted Sichali, Themba Mzembe, Lorrain K Mwaungulu, J Nimrod Mwaungulu, Ruth McNerney, Palwasha Khan, Julian Parkhill, Amelia C Crampin, Taane G Clark
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132840 (2015)
The proportion of tuberculosis attributable to transmission from close contacts is not well known. Comparison of the genome of strains from index patients and prior contacts allows transmission to be confirmed or excluded.In Karonga District, Malawi,
Externí odkaz:
https://doaj.org/article/28d507f52b7f4b53a40d0401f4d8dd4e
Autor:
Sebastian M Mboma, Rein M G J Houben, Judith R Glynn, Lifted Sichali, Francis Drobniewski, James Mpunga, Paul E M Fine, Neil French, Amelia C Crampin
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58192 (2013)
BACKGROUND:The rise in tuberculosis (TB) incidence following generalized HIV epidemics can overwhelm TB control programmes in resource-limited settings, sometimes accompanied by rising rates of drug resistance. This has led to claims that DOTS-based
Externí odkaz:
https://doaj.org/article/b88ef7b98703433386b3ecd66846e8f7
Autor:
Fredrik O Vannberg, Stephen J Chapman, Chiea C Khor, Kerrie Tosh, Sian Floyd, Dolly Jackson-Sillah, Amelia Crampin, Lifted Sichali, Boubacar Bah, Per Gustafson, Peter Aaby, Keith P W J McAdam, Oumou Bah-Sow, Christian Lienhardt, Giorgio Sirugo, Paul Fine, Adrian V S Hill
Publikováno v:
PLoS ONE, Vol 3, Iss 1, p e1388 (2008)
Tuberculosis causes significant morbidity and mortality worldwide, especially in sub-Saharan Africa. DC-SIGN, encoded by CD209, is a receptor capable of binding and internalizing Mycobacterium tuberculosis. Previous studies have reported that the CD2
Externí odkaz:
https://doaj.org/article/3bf431da418046018b6816ba4cdf67fc
Autor:
Themba, Mzembe, Estelle, Mclean, Palwasha Y, Khan, Olivier, Koole, Lifted, Sichali, Venance, Mwinuka, Michael, Kayange, Peter, Mzumara, Andrew, Dimba, Amelia C, Crampin, Judith R, Glynn
Publikováno v:
AIDS (London, England)
Objective: The risk of transmission of Mycobacterium tuberculosis in antiretroviral therapy (ART) clinics is recognized, particularly, when HIV and tuberculosis services are unified, but the degree of potential exposure to patients with infectious tu
Autor:
Jodene Fitness, Lorren Mwaungulu, Amelia C. Crampin, Paul E. M. Fine, D. K. Warndorff, Sian Floyd, Adrian V. S. Hill, Lifted Sichali
Publikováno v:
Europe PubMed Central
Twenty-seven polymorphisms from 12 genes have been investigated for association with tuberculosis (TB) in up to 514 cases and 913 controls from Karonga district, northern Malawi. Homozygosity for the complement receptor 1 (CR1) Q1022H polymorphism wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8a808223f5375ae144700b7eb6df3e5
https://ora.ox.ac.uk/objects/uuid:c4f76978-6f58-4d05-b290-bef26f49d964
https://ora.ox.ac.uk/objects/uuid:c4f76978-6f58-4d05-b290-bef26f49d964
Autor:
Ellis Owusu-Dabo, Bagrey Ngwira, Andrew P. Morris, John O. Gyapong, Andreas Ziegler, Richard A. Adegbola, Thorsten Thye, Lifted Sichali, Ivy Osei, Adrian V. S. Hill, Giorgio Sirugo, Fredrik O. Vannberg, Anthony Enimil, Margaret A. Chinbuah, Fatou Sisay-Joof, Sunny H. Wong, Simon Malema, Sian Floyd, Rolf D. Horstmann, Yik Y. Teo, Christian Lienhardt, Amelia C. Crampin, Kirk A. Rockett, Kerrin S. Small, Melanie J. Newport, Christian Meyer, Paul E. M. Fine, D. K. Warndorff, Tumani Corrah, Philip C. Hill, Dominic P. Kwiatkowski
Publikováno v:
Nature genetics
We combined two tuberculosis genome-wide association studies from Ghana and The Gambia with subsequent replication in a combined 11,425 individuals. rs4331426, located in a gene-poor region on chromosome 18q11.2, was associated with disease (combined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166abd5979178690bc8288d27e166536
https://ora.ox.ac.uk/objects/uuid:16a8ea4b-aaf1-4a4f-bc28-a12a04d69109
https://ora.ox.ac.uk/objects/uuid:16a8ea4b-aaf1-4a4f-bc28-a12a04d69109
Autor:
Paul E. M. Fine, D. K. Warndorff, Chris Wallace, Jorg M. Ponnighaus, Lorren Mwaungulu, J Fitness, A V S Hill, Lifted Sichali, Branwen J. Hennig, David Clayton
Publikováno v:
Genes & Immunity. 5:221-225
Leprosy is a chronic disease caused by infection with Mycobacterium leprae, which is manifested across a wide clinical spectrum. There is evidence that susceptibility both to leprosy per se and to the clinical type of leprosy is influenced by host ge